Gene Information

Name : pyk (Mtc_1752)
Accession : YP_005381014.1
Strain : Methanocella conradii HZ254
Genome accession: NC_017034
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.1.40
Position : 1679599 - 1681350 bp
Length : 1752 bp
Strand : -
Note : IMG term: pyruvate kinase (EC 2.7.1.40)

DNA sequence :
ATGAGGAAGACAAAGATCGTTTGTACGCTGGGCCCCGCGTGCGATACCCAGGACAAGATAGAGGCCCTCATAAAGGCGGG
CATGAACGTCGCAAGGCTTAACATGTCACATGCTACGCACGAATACCATGCAAAATTGATACAGAATGTACGATACGTTT
CTGAGGCGCTGAACGTGCCGATAGGCATCCTAATGGATTTGCAGGGGCCTAAGATACGCATTGGAACGCTAAGCCAAAAG
GTCATCCTTAAGCCAGGGCAGCAATACGTGCTAACCACAAGGGATGTGCCAGGCGATGATAGAGAAGTAAACGTGCCCTT
TAAAGAAATAATAGAATCGGTATCGCCAGGCCAAGCATTGCTCATCGACGATGGCCTCATAGAGCTGACGGTGGAAAGCG
TAAGCGATACCGATATTGTCACAAAGGTCATGAGAGGGGGCGAGCTAAAGGACCGAAAGGGCATAAACCTGCCGCACTCT
ACCGTAAAGATGAGGTCTATCACGGATAAAGACGTAAAAGACCTGCTGTTCGGCATCGACCAGGGCGTCACCACGATAGC
AATGTCCTTCGTCAGGACGCCACAGGACGTGCTGGACCTGAGGAAGATCATCGAGGATAAGGGGGCAGACCTGCCCATAA
TAGCCAAGATCGAGAAACACGAGGCCGTCAAGAACATAGACGGGATAATCGACGTGGTGAACGGCATAATGGTAGCGCGG
GGCGATCTCGGCATAGAGATACCCATGGCGGAAGTGCCCATCGTACAAAAGATGATCATCTCAAAATGTAATGCAAGGGC
TATACCGGTCATAACGGCAACTCAGATGCTCGACTCCATGATAAGGAACCCCATGCCGACCCGCGCAGAGGCAACGGACG
TGGCAAACGCCGTATTCGACGGCACCGACGCCCTCATGCTATCCGGGGAAACCGCCTTTGGAGAATACCCGATAAAAGCG
GTAGAGACCATGGCCCGAATCGCGGAATACACCGAATCGTCCTCCTATTATAAGCACGTCATCGCCGCAAAAATTCCATC
GCCATCCCTGTCCATCACGGATTCTGTGGCCTTTGCGGCCACAGAGGCCGCCCGAAACCTCAAAGCGCAGGCGATCATTA
CAGCAACACAGACCGGCTATTCAGCGAGAAAGGTATCCAAATATAAGCCGCAAATACCCATCTACGCGGTGACCAATAGC
AGTAGCGTCATGTGCCAATTAACTCTATCCTGGGGAATTTTTCCGGTCCGAATAGGGAAGCCCCCGAACCTCGACAGCCT
GATAGATGAATCCGTGAGCTCCTGCCTGAAATATGGCTATATTAAAAATGGCGACCTGGTCGTCATAACGGCCGGGGTAT
TAACCGGCATACCCGGAGGGACCAACATCATGAAGATACACGTAGTTGCAAAAGAAATGGCGCAAGGGATGGGCATTGGA
AAGGGTATAGTAAAAGGCCTCGTTAAGGTCATAACAACCCCTGCCGATTTTGGGCAAATTGAAAAAGGCGATATAATCGC
GATAAAAGAAGCTAACATCGACCGCATCGATGACATAAAGAAGGCGTCTGCCATATTAAGCGAAGAAAGCGGGCTCACGT
CTTTCAGCGCCATCATCGGCAGGGAGATGAGCATACCCGTCGTAGTGGGCATCAAGGACGCTACCACAAGGTTTAAGGAC
GGAATGAAGGTGACAATCGATACTTTAAGCGGCCTAGTATACGAAGGCTACATCAACCTACCCAGCGACTAA

Protein sequence :
MRKTKIVCTLGPACDTQDKIEALIKAGMNVARLNMSHATHEYHAKLIQNVRYVSEALNVPIGILMDLQGPKIRIGTLSQK
VILKPGQQYVLTTRDVPGDDREVNVPFKEIIESVSPGQALLIDDGLIELTVESVSDTDIVTKVMRGGELKDRKGINLPHS
TVKMRSITDKDVKDLLFGIDQGVTTIAMSFVRTPQDVLDLRKIIEDKGADLPIIAKIEKHEAVKNIDGIIDVVNGIMVAR
GDLGIEIPMAEVPIVQKMIISKCNARAIPVITATQMLDSMIRNPMPTRAEATDVANAVFDGTDALMLSGETAFGEYPIKA
VETMARIAEYTESSSYYKHVIAAKIPSPSLSITDSVAFAATEAARNLKAQAIITATQTGYSARKVSKYKPQIPIYAVTNS
SSVMCQLTLSWGIFPVRIGKPPNLDSLIDESVSSCLKYGYIKNGDLVVITAGVLTGIPGGTNIMKIHVVAKEMAQGMGIG
KGIVKGLVKVITTPADFGQIEKGDIIAIKEANIDRIDDIKKASAILSEESGLTSFSAIIGREMSIPVVVGIKDATTRFKD
GMKVTIDTLSGLVYEGYINLPSD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 4e-79 43
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 1e-79 43
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 1e-79 43
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 3e-80 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pyk YP_005381014.1 pyruvate kinase VFG0479 Protein 5e-80 43