Gene Information

Name : Fraau_1723 (Fraau_1723)
Accession : YP_005377814.1
Strain : Frateuria aurantia DSM 6220
Genome accession: NC_017033
Putative virulence/resistance : Virulence
Product : 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1835299 - 1836771 bp
Length : 1473 bp
Strand : -
Note : PFAM: Aldehyde dehydrogenase family; TIGRFAM: 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase

DNA sequence :
ATGATCAAGCACTGGATCAACGGCCGCGAGGTCGAAAGCCGTGAAGTCTTCGAGACCTTCAATCCCGCAACGGGCGATGT
GATCGAGGAGGTGGCCAGTGGTGGTGCCGCCGAAATCGATGCCGCCGTCACTGCCGCCCGCCAGGCCTTTCCCGGATGGG
CCGCCACCCCGGCAAGGGAGCGGGCGCGGCTGATGCGGCGACTGGGCGATCTGATTGATCAGCAGATCCCGCAACTGGCA
GCCCTGGAAACCCGCGATACCGGCTTGCCCATCCATCAGACCCGGAACGTGCTGATTCCCCGGGCCTCGCACAACTTCCG
GTTCTTCTCCGAAGTCTGTACCCGGATGGATGGCCACAGCTATCCGGTGGATGACCAGATGCTCAACTACACCCTGCATC
AGCCCGTCGGCGTGTGCGGACTGATCTCGCCATGGAATGTTCCGTTCATGACGGCCACCTGGAAGACTGCGCCCTGCCTG
GCCCTGGGCAATACCGCGGTATTGAAGATGAGCGAGTTCTCGCCATTGACCGCCCACGAACTGGGCCGGCTGGTACTGGA
GGCCGGTATCCCTGCCGGCGTGTTCAATGTGGTCCAGGGCTATGGTGCCAGTGCCGGCAATGCCTTGGTGCAACATCCCG
ATGTGAGGGCCATTTCCTTTACGGGAGGCACCGAGACCGGCCACACCATTCTCGGCCATGGCGGGGTCAAGAAATATTCC
ATGGAACTGGGCGGCAAGTCACCGGTACTGGTATTCGAAGACGCCGATATCGAACGGGCACTGGATGCGGCCTTGTTCAC
CATCTTTTCCATCAATGGCGAGCGCTGTACCGCCGGCAGCCGGATCTTTGTCCAGGAAAGCGTCCATGACGCCTTCGTCA
CGGCCTTTGCCGAACGTGCCGAGCGGCTGATCCTCGGCGATCCGGAGGACCCTTCCACCCAGATCGGCTCCATGATCACC
TCCCGTCATTACGACAAAGTCACCGGCTATATACGGATCGGCATCGAGGAAGGTGCCCGCCTGCTCGCCGGAGGTCCGGA
ACGCCCCGCCGGCCTGCCCGCCCATCTGGCTCGCGGCCATTTCATACGCCCCACGGTCTTTGCCGACGTCGACAACCGCA
TGCGCATCGCCCAGGAGGAAATTTTCGGCCCGGTAGCCTGCCTGATGAAATTCAAGGACGAGGCCGAAGCACTGCAACTG
GCCAACGACACCCGCTATGGCCTGGCCTCCTATGTCTGGACCCAGGATATCGGGCGCGCCCATCGGGTCGCCCGCGGGAT
CGAGGCCGGCATGGTCTTCATCAACAGCCAGAACGTACGCGATCTGCGCCAGCCCTTCGGCGGCGTCAAGGCCTCGGGAA
CCGGTCGCGAGGGCGGCGAATACAGCTTCGAGGTGTTTACGGAGACCAAGAATGTCTGTGTCTCGATGGGACAGCACCCG
ATTCCACGCTGGGGCCTGCCGAAGGCGCATTGA

Protein sequence :
MIKHWINGREVESREVFETFNPATGDVIEEVASGGAAEIDAAVTAARQAFPGWAATPARERARLMRRLGDLIDQQIPQLA
ALETRDTGLPIHQTRNVLIPRASHNFRFFSEVCTRMDGHSYPVDDQMLNYTLHQPVGVCGLISPWNVPFMTATWKTAPCL
ALGNTAVLKMSEFSPLTAHELGRLVLEAGIPAGVFNVVQGYGASAGNALVQHPDVRAISFTGGTETGHTILGHGGVKKYS
MELGGKSPVLVFEDADIERALDAALFTIFSINGERCTAGSRIFVQESVHDAFVTAFAERAERLILGDPEDPSTQIGSMIT
SRHYDKVTGYIRIGIEEGARLLAGGPERPAGLPAHLARGHFIRPTVFADVDNRMRIAQEEIFGPVACLMKFKDEAEALQL
ANDTRYGLASYVWTQDIGRAHRVARGIEAGMVFINSQNVRDLRQPFGGVKASGTGREGGEYSFEVFTETKNVCVSMGQHP
IPRWGLPKAH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hpaE AAO17179.1 HpaE Not tested tcd island Protein 0.0 76
orf17 AAO17183.1 Orf17 Not tested tcd island Protein 2e-74 42
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 3e-74 42
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 3e-76 41
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 8e-77 41
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 8e-77 41
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 8e-77 41
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 3e-76 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Fraau_1723 YP_005377814.1 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase VFG0082 Protein 1e-76 41