Gene Information

Name : guaA (MRGA327_20965)
Accession : YP_005361940.1
Strain : Mycobacterium tuberculosis RGTB327
Genome accession: NC_017026
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : -
COG ID : -
EC number : 6.3.5.2
Position : 3781765 - 3783294 bp
Length : 1530 bp
Strand : -
Note : COG0518 GMP synthase - Glutamine amidotransferase domain

DNA sequence :
GTGTTGGTGGTCGACTTCGGTGCCCAATATGCCCAGTTGATTGCCCGTCGGGTTCGAGAAGCACGGGTTTTCTCCGAGGT
GATTCCGCACACCGCCTCGATCGAGGAGATCAGGGCCCGTCAGCCGGTGGCGCTCGTGCTTTCCGGTGGACCGGCCAGTG
TCTACGCCGACGGCGCTCCGAAACTCGATCCGGCGCTACTGGACCTCGGTGTACCGGTTCTTGGCATCTGCTACGGGTTT
CAGGCCATGGCGCAGGCGCTCGGGGGGATCGTCGCCCACACCGGCACTCGCGAATACGGTCGGACTGAACTGAAAGTCCT
TGGTGGCAAACTGCATTCGGATCTTCCCGAGGTTCAGCCGGTATGGATGAGTCACGGTGACGCGGTCACGGCCGCGCCGG
ACGGATTCGACGTGGTGGCTAGCAGCGCCGGTGCCCCGGTGGCCGCCTTCGAGGCCTTCGACCGGCGCCTGGCCGGGGTG
CAGTATCACCCGGAGGTGATGCACACCCCACACGGGCAACAGGTGCTCAGCCGGTTTTTGCACGACTTCGCCGGGCTCGG
CGCCCAGTGGACGCCCGCCAACATCGCCAACGCGCTGATCGAGCAGGTGCGCACCCAGATCGGCGACGGCCACGCCATCT
GCGGGCTATCCGGCGGCGTGGATTCCGCGGTGGCCGCGGCCCTGGTGCAGCGGGCCATCGGCGACCGGTTGACCTGTGTC
TTCGTCGACCACGGGCTGTTGCGCGCCGGTGAGCGGGCGCAGGTGCAACGCGATTTCGTGGCCGCCACCGGCGCCAACCT
GGTCACCGTCGACGCGGCCGAGACCTTCCTCGAGGCGCTGTCGGGCGTGAGCGCCCCCGAGGGCAAACGCAAGATCATCG
GCCGTCAGTTCATCCGCGCGTTCGAGGGCGCGGTGCGGGATGTGCTGGACGGTAAGACTGCTGAGTTCCTGGTGCAGGGC
ACGCTGTATCCGGATGTGGTGGAGTCCGGCGGGGGCAGCGGCACCGCGAACATCAAGAGCCACCACAATGTCGGCGGCCT
GCCCGACGACCTGAAGTTCACCCTCGTTGAGCCGCTGCGGCTGCTGTTCAAAGACGAGGTGCGCGCGGTCGGGCGGGAGT
TGGGTCTGCCGGAGGAGATCGTGGCGCGCCAGCCGTTTCCGGGACCGGGGTTGGGTATTCGGATCGTCGGGGAGGTCACC
GCCAAGCGGTTGGATACGCTGCGGCACGCCGATTCGATCGTGCGTGAGGAGCTGACCGCGGCGGGCCTGGACAACCAGAT
CTGGCAGTGTCCGGTGGTGCTGTTGGCCGATGTCCGCTCGGTGGGTGTGCAGGGTGACGGTCGCACCTATGGCCACCCGA
TTGTGCTGCGTCCGGTGTCGAGTGAAGACGCGATGACCGCCGACTGGACCCGGGTGCCCTACGAGGTGCTCGAGCGCATC
TCGACCCGGATCACCAACGAGGTCGCCGAGGTCAACCGCGTGGTGCTGGACATCACCAGCAAGCCGCCCGCCACCATCGA
GTGGGAGTAG

Protein sequence :
MLVVDFGAQYAQLIARRVREARVFSEVIPHTASIEEIRARQPVALVLSGGPASVYADGAPKLDPALLDLGVPVLGICYGF
QAMAQALGGIVAHTGTREYGRTELKVLGGKLHSDLPEVQPVWMSHGDAVTAAPDGFDVVASSAGAPVAAFEAFDRRLAGV
QYHPEVMHTPHGQQVLSRFLHDFAGLGAQWTPANIANALIEQVRTQIGDGHAICGLSGGVDSAVAAALVQRAIGDRLTCV
FVDHGLLRAGERAQVQRDFVAATGANLVTVDAAETFLEALSGVSAPEGKRKIIGRQFIRAFEGAVRDVLDGKTAEFLVQG
TLYPDVVESGGGSGTANIKSHHNVGGLPDDLKFTLVEPLRLLFKDEVRAVGRELGLPEEIVARQPFPGPGLGIRIVGEVT
AKRLDTLRHADSIVREELTAAGLDNQIWQCPVVLLADVRSVGVQGDGRTYGHPIVLRPVSSEDAMTADWTRVPYEVLERI
STRITNEVAEVNRVVLDITSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA NP_938969.1 GMP synthase Not tested Not named Protein 0.0 78
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 3e-130 51
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 3e-130 51
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 2e-130 51