Gene Information

Name : OCU_20030 (OCU_20030)
Accession : YP_005337543.1
Strain : Mycobacterium intracellulare ATCC 13950
Genome accession: NC_016946
Putative virulence/resistance : Virulence
Product : 2,3-dihydroxybenzoate-AMP ligase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2070336 - 2071973 bp
Length : 1638 bp
Strand : -
Note : -

DNA sequence :
ATGACCCCGAACACAACGCCGCCGGCCGGAGTCCTCAACGGGTTCGTGCCCTTCCCCGCTGATCGCGCCGCCGCCTACCG
GGCGGCCGGCTATTGGGCGGGACGGACGCTGGACACGATCCTGACCGACGCGGCTCGGCAGTGGCCCGATCGAACCGCGG
TGCGCGACGCCGTGGGCGGTACCGGCTTCAGTTATGCGGACCTCGACGACCAGGCTAACCGCGCGGCCGGCGGCCTGCGG
GCACTGGGTATCGCGCCGGGCGACCGGGTGCTGCTGCAGTTGCCGAACAGCTGCCAGTTCGCGGTGGCCTTATTCGGGTT
GCTGCGGGCGGGGGCGGTCCCGGTGATGTGCCTGCCGGGACACCGGGCCGCCGAGCTCGGGCATTTCGCCGCGGTCAGCG
CGGCCACCGGTCTGTTGATCGCCGATACCGCGGCGGGTTTCGACTATCGCACGATGGCGCTCGGCCTCATCGAGGAACAC
CCCACGCTGCGGCACGTCATCGTCGACGGCGACCCGGGGCCGTTCACCTCGTGGGCGCAGTTGTGCGAGCAGGCGCCCGG
CCCGCCGTCCTCGGCCGACCCGGGATCGCCTGCGCTGCTTCTGGTTTCCGGCGGGACCACGGGCACACCCAAGCTCATCC
CCCGCACCCACGACGATTACGTGTTCAACGCGACGGCCAGCGCCGAACTCTGCCGGCTCACCTGCGATGACGTCTATCTG
GCGGTGCTGTCGGCCGGACACAATTTTCCCCTCGCCTGTCCTGGCCTGCTCGGCGCGATGACGGTGGGCGCCACCACCGT
CTTCGGCACCGATCCCAGCCCCGAGGCGGCCTTCGCCGCCATCGACCGCCACGGCGTCACGGTCACCGCCCTGGTGCCGG
CCCTGGCCAAACTGTGGGCGCAGGCCTGCGAGTGGGAACCGGTGACTCCAAAAACCTTGCGGCTCTTACAAGTCGGTGGC
GCCAAGCTGGAGCCCGAGGACGCCCGCCTGGTGCGCACCGCCTTGACGCCGGGCCTGCAGCAGGTGTTCGGGATGGCCGA
GGGGCTGCTGAACTACACGCGCCCCGACGATCCGCCCGAACTCACCGAGCACACGCAGGGCCGGCCGTTGTCCGCCGCCG
ACGAACTGCGCGTCGTCAATGCGGCCGGCGAGCCCATGCCCCCCGGCGAGGAAGGCGAATTGCTGGTCCGCGGACCCTAC
ACGTTCAACGGCTACTTTCGCGCCGAGCGCGACAACGAGCGCTGCTTTGACGCGCAAGGCTTCTTCCGCAGCGGTGACCT
GGTCCGGATCACCGACGACGGCTACGTCGTGGTCACAGGCCGCGTCAAAGACGTCATCTGCCGCGGCGGCGAAACCATCT
CCGCGGCGGACCTCGAGGAGCAGATGCACAGCCACCCGGCGATCTTCTCGGCGGCCGCGGTGGCGCTCCCCGACCCTTAT
CTGGGCGAGAAGATCTGTGCGGCAATAGTTTTCAACGGTCCTGAGCTATCGCTCGCGGAGCTTAACGGCTACCTCGACGG
GCGTGGCGTGGCCGCGCACGCGCGTCCCGACGTCTTGGTTCCGATGACCACGCTGCCCACCACGCCGATCGGCAAGATCG
ACAAAAAGGCGATCGCCGGCCAGATTTCGGCGCGCTAG

Protein sequence :
MTPNTTPPAGVLNGFVPFPADRAAAYRAAGYWAGRTLDTILTDAARQWPDRTAVRDAVGGTGFSYADLDDQANRAAGGLR
ALGIAPGDRVLLQLPNSCQFAVALFGLLRAGAVPVMCLPGHRAAELGHFAAVSAATGLLIADTAAGFDYRTMALGLIEEH
PTLRHVIVDGDPGPFTSWAQLCEQAPGPPSSADPGSPALLLVSGGTTGTPKLIPRTHDDYVFNATASAELCRLTCDDVYL
AVLSAGHNFPLACPGLLGAMTVGATTVFGTDPSPEAAFAAIDRHGVTVTALVPALAKLWAQACEWEPVTPKTLRLLQVGG
AKLEPEDARLVRTALTPGLQQVFGMAEGLLNYTRPDDPPELTEHTQGRPLSAADELRVVNAAGEPMPPGEEGELLVRGPY
TFNGYFRAERDNERCFDAQGFFRSGDLVRITDDGYVVVTGRVKDVICRGGETISAADLEEQMHSHPAIFSAAAVALPDPY
LGEKICAAIVFNGPELSLAELNGYLDGRGVAAHARPDVLVPMTTLPTTPIGKIDKKAIAGQISAR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 4e-80 42
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 3e-80 42
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-79 42
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-79 42
ybtE CAA21394.1 - Virulence HPI Protein 1e-79 42
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 1e-79 42
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 2e-79 42
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-79 42
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 1e-79 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
OCU_20030 YP_005337543.1 2,3-dihydroxybenzoate-AMP ligase VFG1817 Protein 1e-177 79
OCU_20030 YP_005337543.1 2,3-dihydroxybenzoate-AMP ligase VFG0168 Protein 2e-77 45
OCU_20030 YP_005337543.1 2,3-dihydroxybenzoate-AMP ligase VFG0932 Protein 3e-68 41