Gene Information

Name : metB (BLASA_4026)
Accession : YP_005330880.1
Strain : Blastococcus saxobsidens DD2
Genome accession: NC_016943
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : -
COG ID : -
EC number : 2.5.1.48
Position : 3891357 - 3892505 bp
Length : 1149 bp
Strand : +
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 87326410, 90148970, 9843488; Product type e : enzyme

DNA sequence :
ATGAGCGAGCTCGCGGGATTCAACACCCGCGCCATCCACGCCGGGCAGGAGCCCGACCCCGCGACCGGCGCGGTCATCCC
GCCGCTGCACCTGACGACGACCTACAAGCAGGACGGCGTCGGCGGGCTGCGCGGCGGCTACGAGTACAGCCGCAGCGGGA
ACCCGACCCGTGCCGCGCTGCAGGAACAGCTCGCGGCCCTGGAGCAGGGCACCACGGCCCTGACCTTCGCCTCCGGCCTC
GCCGCCGAGGACACCCTGCTGCGCACCCTCTGCCGGCCGGGCGACGAGATCGTCCTGGGCGGCGACGCCTACGGCGGGAC
GTTCCGGCTGATCTCCCGGGTGCTCGAGCCCTGGGGCGTCGGCTACCGGCCGATCGACCTGGGCGACCTGGACGCCGTCC
GGGAGGCCGTCGCGCCCGAGACCACCCGGGTCGTCTGGTGCGAGACGCCGACCAACCCGCTGCTCAACATCGCCGACATC
GCCGCGCTGGCGCAGATCGCGCGCGAGAGCGGCACCGTGCTCGTCGTCGACAACACCTTCGCCTCGCCCTACCTGCAGCG
GCCGCTGACGCTCGGGGCCGACGTCGTCGTGCACTCGACCACCAAGTACCTGGGCGGGCACTCCGACGTCGTCGGCGGAG
CGCTGGTGACCAGCGACGCGCACTGGGCCGAGCGGCTCACCTACCACCAGAACGCCATGGGAGCGGTGAACGGCCCCTTC
GACGCCTGGCTGCTGATGCGCGGGATCAAGACCCTCGGCGTGCGGATGGACCGGCACTGCGCCAACGCGGCCCGGATCGC
CGAGTTCCTGCTCGACCATCCCGCGGTGGCCTCGGTGCTCTACCCGGGGCTGCCCGACCACCCGGGGCACGAGATCGCCG
CGCGGCAGATGTCCGGCTTCGGCGGGATGCTGTCGTTCCGGCTGCGCGACGGCGAGGAGGCCGCGCTGCGGGTCTGCGAG
CGCACCCGGCTGTTCACGCTCGCGGAGTCCCTCGGCGGCGTCGAGTCGCTCATCGAGCACCCCGGCCGGATGACCCACGC
GAGCGCCGCCGGCTCACCGCTGGAGGTGCCCGCCGACCTCGTGCGGCTCTCGGTGGGCATCGAGGACGTCGAGGATCTGC
TGGCCGACCTGGACCGGGCGCTCAGCTGA

Protein sequence :
MSELAGFNTRAIHAGQEPDPATGAVIPPLHLTTTYKQDGVGGLRGGYEYSRSGNPTRAALQEQLAALEQGTTALTFASGL
AAEDTLLRTLCRPGDEIVLGGDAYGGTFRLISRVLEPWGVGYRPIDLGDLDAVREAVAPETTRVVWCETPTNPLLNIADI
AALAQIARESGTVLVVDNTFASPYLQRPLTLGADVVVHSTTKYLGGHSDVVGGALVTSDAHWAERLTYHQNAMGAVNGPF
DAWLLMRGIKTLGVRMDRHCANAARIAEFLLDHPAVASVLYPGLPDHPGHEIAARQMSGFGGMLSFRLRDGEEAALRVCE
RTRLFTLAESLGGVESLIEHPGRMTHASAAGSPLEVPADLVRLSVGIEDVEDLLADLDRALS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-72 46
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-73 46
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 8e-55 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
metB YP_005330880.1 cystathionine gamma-synthase BAC0207 Protein 8e-71 47