Gene Information

Name : hsdM (SGRA_4133)
Accession : YP_005324432.1
Strain : Saprospira grandis Lewin
Genome accession: NC_016940
Putative virulence/resistance : Virulence
Product : restriction/modification methyltransferase
Function : -
COG functional category : -
COG ID : -
EC number : 2.1.1.72
Position : 4259166 - 4261508 bp
Length : 2343 bp
Strand : -
Note : COG0286 Type I restriction-modification system methyltransferase subunit

DNA sequence :
ATGAATACAGCTGTTCATAATAAATTGGTGTCCTTTATTTGGTCTATTGCAGATGATTGTTTGCGAGATATTTATGTGCG
TGGAAAGTACCGTGATGTGATTTTGCCCATGGTGGTTTTGCGGCGTTTGGATGCTTTGTTGGAAGATACAAAGGAAGCCG
TTTTGGAAGAGGCGTATTTTCAGAAGGAGGTGATGAAGTTGGTGGATTGGGATGAGCATGCTTTGCAGCATGCTTCGGGC
TATGTTTTTTATAATACGAGTACGTGGACCTTGCAACGGTTCTATGAGCGGACAAGTAATAACCCCCAGTTGTTGTTGGC
CAATTTTGAGGAGTACTTGCTGGGCTTTAGCCAAAATGTGCAGGAGATTATTGAGAAGTTTAACCTCAGGGCGCAAATTC
GCCATATGGTGAATAAGGATGTGCTTCTGGCGGTGGTGGAGAAGTTTATATCGCCTGGTATTAACCTGACCAATCAGGAT
AAGCTAGACCCTGAGGGGAATAAGCTGCCCGCTTTGACTAACTTGGGGATGGGCTATGTCTTTGAGGAGTTGATTCGGAA
GTTTAATGAGGAAAACAATGAGGAAGCGGGGGAGCATTTTACGCCCAGAGAGGTCATTGATTTAATGAGCCGTTTGGTCT
TTTTGCCGATTAAGGAGGCCTTGCCCAAGGTGATGACGATTTATGATCCCGCTTGTGGATCGGGGGGGATGCTGACCGAG
GCGCAGAATTTTGTGAAAGATGAGGAGGGGGAAATCCGTTGTACGGATCATGATGTATACCTCTTTGGCAAAGAGATCAA
TGATGAAACCTATGCGATTTGTAAGTCGGATATGATGATTAAGGGGAATGACCCCGCAAATATCCGCAGTGGCTCTACCT
TATCTACCGATGAGTTTGCGGGTTTGCAGTTTGATTTTATGCTCTCTAATCCGCCCTATGGCAAGTCTTGGAGCTCGGAG
AAGAAGTATATTGATGGTGTAGATGGCACCGATGTTCGTTTTTTAGTGCCGCTCAAAGATTATTGGGGGAAAGAAGAAAT
TGTGGCGGCTACGCCCCGCTCTTCTGATGGGCAGTTGCTCTTTTTGATGGAAATGTTGAGCAAGATGAAGACCGAAAGTC
CTACGGGCTCTCGGATTGCTTCTGTGCATAATGGCTCGAGTTTGTTTACGGGCGATGCGGGCAGCGGAGAGAGCAATATC
CGTCGCTATTTGATAGAGCAAGATTATTTGGAGGCGATTATACAGTTGCCCAACAACCTCTTTTACAATACGGGGATCAC
GACCTATATTTGGTTGTTGAGCAATCGGAAGTCGGCAGAGCGGGCCGGCAAAGTACAGTTGATTGATGCGAGTCAGTTGT
ATCAGAAGTTGCGTAAGAACTTGGGAGATAAGAACTGTGAGTTATCGCAGGCGCATATTGGGGAGATTCTATCGGTTTAT
CAGGAATTGGCGACTGTAGAGCGGCAGGGAGAAGAGGGCATTGCGGCTCAGGTTTTTGAGAACCAGGATTTTGGCTATTA
TAAGGTCAATATAGAGCGGCCACAGCGTTTGCGGGCTAAATTTAGTGCGGAGGCCATTGAAAGTCTGCTTTATCAGCGAG
GTTTAGAAGCGCCTATGCGTTGGGCCTATGCCGAATTTGGGGAGGATGTTTATCAGCAGTTGGGGCAGCATAAGAAAGCG
CTTTTGGCCTATTGTGAGGCGGAGGGCATTTCTTTGTCGGCCAAGCAAAAAACGGCCTTAACCACCGCCAAGGGCTGGGA
AAAAGGGCAGGCCCTTTATGCTGCGGCCCAGCAGTTGATGCAGGCCATAGGGGAGCAGGTCTATTTTGATTTCAATCAGT
TTGTAGCAGCGCTAGCAAAGCAGATCAAGGCCTTGGGGCTAAAGCTATCGGCCACAGAGAAAAAGGCCATTTATTCGGCA
GTAAGTACTTATGATGCCAAGGCCGAAAAGGTCATTAAGCGCCGCTTGAAGTTGAGCGGCCAAAAGCTAACAAACTTATT
GGCTCATTTGGGTTGTACGCTAGAGCAGCTGCCCGACTTTGGCTATTATCCCAGCGGAAAGGCGGGCGAATACTTGGAGT
ATGAAAGCGAAAGCAGCTTGAGAGATAGCGAAAACATTCCCTTAAAGGAAGAGATTCATAGCTACTTCTTAGAGGAAGTG
CGTCCGCATATTGCCGAGGCTTGGATCAATCTGGATAGCGTAAAGCTGGGCTATGAGATTAGCTTCAACAAATATTTTTA
TCGTCATCAGCCCTTGCGCTCCCTAGAAGAAGTGAGTCAGGAGATCAGAACGCTAGAAGCAGAAAGCGATGGATTGATTG
CAGAAATTTTAAAGTTGGTATAA

Protein sequence :
MNTAVHNKLVSFIWSIADDCLRDIYVRGKYRDVILPMVVLRRLDALLEDTKEAVLEEAYFQKEVMKLVDWDEHALQHASG
YVFYNTSTWTLQRFYERTSNNPQLLLANFEEYLLGFSQNVQEIIEKFNLRAQIRHMVNKDVLLAVVEKFISPGINLTNQD
KLDPEGNKLPALTNLGMGYVFEELIRKFNEENNEEAGEHFTPREVIDLMSRLVFLPIKEALPKVMTIYDPACGSGGMLTE
AQNFVKDEEGEIRCTDHDVYLFGKEINDETYAICKSDMMIKGNDPANIRSGSTLSTDEFAGLQFDFMLSNPPYGKSWSSE
KKYIDGVDGTDVRFLVPLKDYWGKEEIVAATPRSSDGQLLFLMEMLSKMKTESPTGSRIASVHNGSSLFTGDAGSGESNI
RRYLIEQDYLEAIIQLPNNLFYNTGITTYIWLLSNRKSAERAGKVQLIDASQLYQKLRKNLGDKNCELSQAHIGEILSVY
QELATVERQGEEGIAAQVFENQDFGYYKVNIERPQRLRAKFSAEAIESLLYQRGLEAPMRWAYAEFGEDVYQQLGQHKKA
LLAYCEAEGISLSAKQKTALTTAKGWEKGQALYAAAQQLMQAIGEQVYFDFNQFVAALAKQIKALGLKLSATEKKAIYSA
VSTYDAKAEKVIKRRLKLSGQKLTNLLAHLGCTLEQLPDFGYYPSGKAGEYLEYESESSLRDSENIPLKEEIHSYFLEEV
RPHIAEAWINLDSVKLGYEISFNKYFYRHQPLRSLEEVSQEIRTLEAESDGLIAEILKLV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC1769 NP_231404.1 DNA methylase HsdM Not tested VPI-2 Protein 0.0 67
VC0395_A1367 YP_001217310.1 DNA methylase HsdM Not tested VPI-2 Protein 0.0 67
VPI2_0017c ACA01834.1 DNA methylase HsdM Not tested VPI-2 Protein 0.0 67

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
hsdM YP_005324432.1 restriction/modification methyltransferase VFG1102 Protein 0.0 67