Gene Information

Name : wbpO (SGRA_3991)
Accession : YP_005324290.1
Strain : Saprospira grandis Lewin
Genome accession: NC_016940
Putative virulence/resistance : Virulence
Product : nucleotide sugar dehydrogenase
Function : -
COG functional category : -
COG ID : -
EC number : 1.1.1.-
Position : 4105841 - 4107133 bp
Length : 1293 bp
Strand : +
Note : COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase

DNA sequence :
ATGTATCAAGCACTTATTGCCCAAGAAAAGAAATTAGCAGTTATTGGTCTAGGTTATGTGGGCTTGCCCATCGCCTTGGC
CTTTGCCAAAAAACTATCGGTTATTGGTTTTGACATCAATGCCGAAAGAGTGGCCCAAATGCAGCAGCAGCAAGACCCCT
CTAAGGAGTTGGATGCCCAAGCTTTTGAAGGAGCAGATATTGTCTTTAGCCATGAGCTAGAGGATTTGCGCCAAGCCCAT
TTTTATGTGGTGGCCGTGCCTACGCCTATTGATAGCCATCGCAGCCCCAATCTTCATCCTTTGCTCTCGGCCTCCAAAAC
GGTGGGCCAAGTGCTCAAAAAAGGCGATTATGTCGTTTTTGAGTCTACGGTTTATCCCGGTTGCACCGAAGAAGATTGTG
TCCCTATCCTAGAAGCCGAATCGGGCCTAAAGGCGGGCCTAGATTTTAAAGTGGGCTATTCGCCCGAGCGCATTAACCCC
GGAGATAAGGAGCGCACCATCGAGAAGATTGTCAAGGTGGTTTCTGGAAATGATGAAGAGGCCCTAGAAAACATTGCCCA
AACCTATGAGCTCATTATTGAGGCCGGGGTGCATCGGGCCAGCAGCATCAAGGTAGCCGAGGCCGCCAAGGTCATTGAAA
ATACCCAGCGCGACCTCAACATTGCTTTGATGAATGAGCTCTCTATCATTTTTGATAAAATGGACATCAATACCTATGAG
GTCTTGAAAGCCGCAGGGACCAAATGGAACTTCCTTAATTTTTATCCGGGCCTAGTGGGCGGCCACTGTATTGGGGTAGA
CCCTTATTACTTGACCTACAAAGCGCAGCAGCTCAATTATAATCCTCAAGTAATTTTGAGTGGCCGCCGCATCAATGATA
ATATGGCCGAATATGTGGCCAAAAAGGCCTTGCAGTTTATTTTGCAGACCGATACGCATCCCAAATCGGCCAAGGTATTG
GTGAAGGGCATTACCTTTAAGGAAAATGTAGCCGATATTCGCAACTCTAAAGTGGCGGATTTGATTGCGGCCCTAAAAGA
TTATGCCTTGCAAGTAGAGGTGGTTGACCCCTATGCCGCAGCCGATGAAGTGGCCCATGAATACGGCATCGAATTGGCCC
AGGAGGTTGGAACAGACTACGATGTTGTCATTGTGGCCGTAGCCCATGAGGAATACAAGCAGCTAGATGCCGCTTATTTT
CGTTCTATAAGCAAAGAGGGCGCGCCTATTTTGGACCTCAAAAACCTATATGCGAATTGGGCCGAAGATTTGCCCCTTCG
TTGGACACTTTAG

Protein sequence :
MYQALIAQEKKLAVIGLGYVGLPIALAFAKKLSVIGFDINAERVAQMQQQQDPSKELDAQAFEGADIVFSHELEDLRQAH
FYVVAVPTPIDSHRSPNLHPLLSASKTVGQVLKKGDYVVFESTVYPGCTEEDCVPILEAESGLKAGLDFKVGYSPERINP
GDKERTIEKIVKVVSGNDEEALENIAQTYELIIEAGVHRASSIKVAEAAKVIENTQRDLNIALMNELSIIFDKMDINTYE
VLKAAGTKWNFLNFYPGLVGGHCIGVDPYYLTYKAQQLNYNPQVILSGRRINDNMAEYVAKKALQFILQTDTHPKSAKVL
VKGITFKENVADIRNSKVADLIAALKDYALQVEVVDPYAAADEVAHEYGIELAQEVGTDYDVVIVAVAHEEYKQLDAAYF
RSISKEGAPILDLKNLYANWAEDLPLRWTL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cap1L AAA64651.1 type 1 capsule synthesis gene Virulence SCCcap1 Protein 3e-103 54
tviB NP_807945.1 VI polysaccharide biosynthesis UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 2e-101 51
tviB NP_458740.1 Vi polysaccharide biosynthesis protein, UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 2e-101 51

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
wbpO YP_005324290.1 nucleotide sugar dehydrogenase VFG0431 Protein 1e-101 51