Gene Information

Name : metC (SGRA_3011)
Accession : YP_005323323.1
Strain : Saprospira grandis Lewin
Genome accession: NC_016940
Putative virulence/resistance : Resistance
Product : cystathionine gamma-lyase
Function : -
COG functional category : -
COG ID : -
EC number : 4.4.1.8
Position : 3096400 - 3097539 bp
Length : 1140 bp
Strand : -
Note : COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases

DNA sequence :
ATGAAATTCGGAACCAAAGTCATTCACGCAGGTATTGAACCCGATCCCGCAACGGGAGCGATTATGACGCCCATTTATCA
GACTTCTACTTATGCCCAAAGCTCTCCGGGCCAACATAAAGGTTATGAGTATTCTAGAACGCTCAACCCGACCCGCAAAG
CCCTAGAAGATAACTTGGCTGCCCTAGAAAATGGACAGTTTGGCCTTACTTTCGGCTCTGGCCTTGCCGCAGAAGCTGCC
CTTTTGCACCTGCTCGATCCAGGCGATGAGGTGATTTCTACCAACGACCTTTATGGCGGATCTTACCGCCTCTTTACGAA
GGTCTTTAGCCGCTATGGCATCAAGTTTCAGTTTGTAGGGATGCAGGGCACCGCCGAAATTGAGGCCCATATTACCGAAA
AAACTAAGCTCATTTGGGTAGAAACGCCCACCAACCCCATGCTCAATATTATTGATATTGAGGCCATTTGTGCCGTAGCC
AAAAAGCACAATATCATGGTTTGTGTAGACAATACTTTTGCTACGCCTTACCTCCAAAACCCCTTGGACCTTGGCGCCGA
TATCGTCATGCACTCGGTGACTAAATACCTAGGTGGCCACTCTGATGTGGTGATGGGTGCTTTGGTGGTCAAGGATGAAG
CCTTGGCCGAAAAACTCTACTTTATCCAGAATTCTGTGGGCGCCGTTCCTGGTCCCCAAGATTGCTTCTTGGTCCTTCGT
GGCATCAAAACTCTACATCTTCGGGTGCAAAGAGCGAGCGAAAATGCCGCTAAAATTGCCGACTTCTTGATGCAGCACCC
CAAGGTAGACAAGGTGTATTATCCTGGTTTGGCCCATCATGCGGGACATGAAACTGCCAAAAAGCAGATGCGCGGCTTTG
GCGCTATGCTTTCCTTTAATCTCAAGGAGGATACCGCAGAAGCTGCCGCTAAGGTGCTCGAAAAAGTACATTATTTCACT
TGTGCCGAGTCTTTGGGTGGCGTAGAATCACTCATTGGCCATCCTGCTAGCATGACGCATGCGGCTATTCCCCGCGAAGA
GCGCCTCAAAGTGGGCTTGACCGACTCGATCATTCGCCTTTCTGTTGGGGTAGAAGATGCCGATGACCTTTTGGCTGATT
TAGATAAGGCCCTAGGATAG

Protein sequence :
MKFGTKVIHAGIEPDPATGAIMTPIYQTSTYAQSSPGQHKGYEYSRTLNPTRKALEDNLAALENGQFGLTFGSGLAAEAA
LLHLLDPGDEVISTNDLYGGSYRLFTKVFSRYGIKFQFVGMQGTAEIEAHITEKTKLIWVETPTNPMLNIIDIEAICAVA
KKHNIMVCVDNTFATPYLQNPLDLGADIVMHSVTKYLGGHSDVVMGALVVKDEALAEKLYFIQNSVGAVPGPQDCFLVLR
GIKTLHLRVQRASENAAKIADFLMQHPKVDKVYYPGLAHHAGHETAKKQMRGFGAMLSFNLKEDTAEAAAKVLEKVHYFT
CAESLGGVESLIGHPASMTHAAIPREERLKVGLTDSIIRLSVGVEDADDLLADLDKALG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 3e-80 50
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-81 50
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 6e-57 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
metC YP_005323323.1 cystathionine gamma-lyase BAC0207 Protein 2e-63 42