Gene Information

Name : SGRA_1893 (SGRA_1893)
Accession : YP_005322211.1
Strain : Saprospira grandis Lewin
Genome accession: NC_016940
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : -
COG ID : -
EC number : 1.2.1.3
Position : 1901656 - 1903176 bp
Length : 1521 bp
Strand : +
Note : COG1012 NAD-dependent aldehyde dehydrogenases

DNA sequence :
ATGCAAGAAACAAATGTAATGGATGAAGTCCTAAAAGCTCCCGACTTCAAACCTCAATACGAAAACTTTATCAACGGAGA
ATGGGTAAAACCTACCAATGGCGAGTACTTCGAAAATGTATCTCCCGTAGACGGTAAAAGCTTTACGCTTATCCCCCGCT
CTACCAAAGAAGATATTGATAAGGCCGTAGCCGCCGCCTGGGCCGCCGCTCCAGAATGGAACAATAGCTCGGCCACTTTC
CGTAGCAATATTCTACTCAAGATTGCCGACCGTATGGAGGAAAATCTTGAACTACTCGCTCGTACCGAAACTTGGGACAA
TGGTAAGGCCATTCGCGAAACTCGCGCAGCCGATATGCCCCTAGCTATCGACCATTTCCGCTATTTTGCTGGCGTTATCC
GCGCTGAAGAAGGTAGCATGAGCGAACTCGATGCTAATACAGTTTGTATCAATGTCCAAGAACCCCTAGGCGTAGTGGCC
CAGATTATTCCCTGGAACTTCCCGCTCCTTATGGCTGCTTGGAAAATCGCTCCCGCTCTAGCCGCTGGTAACTGCGTAGT
CCTTAAACCCGCAGAGCAAACTCCTGTAGGTATCCTAATTCTAATGGAGCTTATTCAAGATATTTTACCCAAAGGCGTGC
TGAATGTAGTCAACGGTTTTGGCGTAGAAGCAGGTAAACCCCTAGCTTCTCACCCCGATGTACGCAAGGTGGCCTTTACC
GGAGAAACGACTACCGGTCAGCTCATTATGCAGTATGCTTCTAAAAACTTGATTCCCGTTACTTTGGAATTGGGCGGTAA
GTCGCCCAACGTTTTCTTCGCTAACGTGATGGCAGAAGATGATGCCTTCTTCGATAAATGCCTAGAAGGGGCCGCTATGT
TTGCCCTCAACCAAGGAGAAGTTTGTACTTGCCCCTCCCGCATTTTGGTCCAAGAAAGTATCGCCGATAAGTTTATCGAA
CGCCTAATCGAACGCGTCAACGCCATTAAGATGGGCCACCCCCTAGATCCTAACACCATGATGGGCGCACAAGCTTCTAA
CGATCAATACGAGAAAATCCTCAACTATATCAAAATTGGTAAAGAAGAAGGTTGCGAAGTCTTGGCAGGTGGCGCCGCCG
CTGCAGTAGATAGCCTCTCTGGTGGATACTATATCCGCCCCACTATCCTAAAAGGACACAACAAAATGAGAGTCTTCCAA
GAAGAAATTTTTGGCCCAGTCGTTTGTATTACCACCTTTAAGGATGAAGCCGAAGCCGTAGAAATTGCCAATGATACCCT
CTACGGACTAGGCGCTGGCGTATGGACACGCGATATGCACCAAGCTTACCAAATCTCTAGAAAAATTGAAGCCGGACGCG
TTTGGGTCAATAACTATCACGCTTATCCCGCTCACGCTCCTTTTGGTGGCTATAAAAAATCCGGAATCGGACGCGAAAAT
CACAAGATGATGCTCGCACACTATCGCCAAACCAAAAATATGCTCATCTCTTACGATAAGAACGCTCTCGGATTCTTCTA
A

Protein sequence :
MQETNVMDEVLKAPDFKPQYENFINGEWVKPTNGEYFENVSPVDGKSFTLIPRSTKEDIDKAVAAAWAAAPEWNNSSATF
RSNILLKIADRMEENLELLARTETWDNGKAIRETRAADMPLAIDHFRYFAGVIRAEEGSMSELDANTVCINVQEPLGVVA
QIIPWNFPLLMAAWKIAPALAAGNCVVLKPAEQTPVGILILMELIQDILPKGVLNVVNGFGVEAGKPLASHPDVRKVAFT
GETTTGQLIMQYASKNLIPVTLELGGKSPNVFFANVMAEDDAFFDKCLEGAAMFALNQGEVCTCPSRILVQESIADKFIE
RLIERVNAIKMGHPLDPNTMMGAQASNDQYEKILNYIKIGKEEGCEVLAGGAAAAVDSLSGGYYIRPTILKGHNKMRVFQ
EEIFGPVVCITTFKDEAEAVEIANDTLYGLGAGVWTRDMHQAYQISRKIEAGRVWVNNYHAYPAHAPFGGYKKSGIGREN
HKMMLAHYRQTKNMLISYDKNALGFF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 6e-147 63
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 1e-152 62
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 1e-152 62
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 1e-152 62
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 5e-152 62
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 4e-73 42
hpaE AAO17179.1 HpaE Not tested tcd island Protein 3e-72 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SGRA_1893 YP_005322211.1 aldehyde dehydrogenase VFG0082 Protein 3e-147 63