Gene Information

Name : wbtA (FTU_1482)
Accession : YP_005306071.1
Strain : Francisella tularensis TIGB03
Genome accession: NC_016933
Putative virulence/resistance : Virulence
Product : UDP-N-acetylglucosamine 4 6-dehydratase
Function : -
COG functional category : -
COG ID : -
EC number : 4.2.1.-
Position : 1590465 - 1592033 bp
Length : 1569 bp
Strand : -
Note : -

DNA sequence :
ATGGCTAGTTGGCGTAAGTCGACTCAAAAAACTTTTTTACGTAAGGCTTTTATTAATTTGCCAGTATTTTTCATAGTGGC
ATTATTTTTTTATGGCAAAGTCACTTTTTCGTTGATATTCTCTGAGTTTTTATTTTATGTTTTTTTGATCAGTTTAAGTG
TCTACTTTTATTGGTATTTGATGAACAGAGGATCAGTGGATAAAAGTAAAACTGCGGTTATTTATGGTGCAGGTGCTGCA
GGAACAAAGATTGCTCAAGAACTTGCTTCTGCTGGTTATCGCATCAAATGTTTTGTTGATGACAATGAAACTTTACAAAA
AAGAAGTATTGATAGTAAAAAGGTTCTATCTAAAGCTGAATTAACAAAACTATTGCTATCTAGTAGATTTGACCTTTTGG
TTATTGCATTGCCAAGAAATGCAAACCAAGTAGTCAAAAATATATATAAAGAATTTGAAAAGGATTTTAATCAGATTAGA
ATTATGCCGCCTCTTGAGGAAATTCTTCAAGATGAGAATTTTATGTCACAGTTGAAGCCTGTTTCACTCTATGATCTATT
AGCGCGTGATACTAAGAGTTTAGATAAAGAATCTATCTCTAATTTTATCAAAAATAAGGTGGTGCTAGTCACAGGAGCTG
GAGGTAGTATAGGTTCTGAAATAGTACATCAATGTATCAAGTATCAGGCAAAAGAGTTGATATTGGTTGATCATAGTGAG
TTTAACTTATATAAAATTACTGAGGAGTGTAGTCATTTTAATATCAATAGTGTGCTATGTTCTGTTTGTGATAGAAAAGC
ATTGGCTGAGGTTTTTCAAAAGTATACTCCAAATATAGTATTTCATGCTGCTGCCTACAAGCATGTTCCCTTAGTTGAGG
AGAATATCTCTAGAGCAATTAGAAATAATATCTTAGGTACTAAGAATGCTATAGATCTGGCTATAGAAGCTGGTGTTGAG
TCATTTATATTGATTTCCACTGATAAAGCAGTGCGACCAACGAATGTTATGGGGGCTACCAAGAGAGTTTGTGAGCTGTA
TTTACAGAATGTTGATCCCAAAAATACCAAGCTTGCTGCAGTGCGTTTTGGTAATGTGCTTGGTAGTAGTGGCAGTGTGA
TTCCAAAATTTGAAGAGCAAATAAGAAAAGGTGGTCCTGTTACAGTTACTCATCCTGAAATTACACGTTATTTTATGTTG
ATACCAGAAGCTTGTGAACTGGTCCTACAAGCTGGTGCTATTGCAAAAAATTCAGAGGTCTTTGTCTTAGATATGGGGCA
ACCTGTCAAGATTATTGATCTTGCTAAACAATTTATTAGACTTTCTGGTAGAGGTGATATTGATATTAAAATAGTTGGTT
TGCGTCCAGGAGAGAAACTTTACGAAGAGCTTTTGATAGAGGAAGATGATGTTAGTACCGACTATAAAGATATTTTTATT
GGTAGAAGGACTTTTTACGATATTAATACTCTAAACCAAGATATTGAATCGTTGATCAAGGATGATGTTGATCAGCTTGT
GATATTAAAGAAAATTGTTCCGGAATTTGAACATAGATTGAATGGGTAG

Protein sequence :
MASWRKSTQKTFLRKAFINLPVFFIVALFFYGKVTFSLIFSEFLFYVFLISLSVYFYWYLMNRGSVDKSKTAVIYGAGAA
GTKIAQELASAGYRIKCFVDDNETLQKRSIDSKKVLSKAELTKLLLSSRFDLLVIALPRNANQVVKNIYKEFEKDFNQIR
IMPPLEEILQDENFMSQLKPVSLYDLLARDTKSLDKESISNFIKNKVVLVTGAGGSIGSEIVHQCIKYQAKELILVDHSE
FNLYKITEECSHFNINSVLCSVCDRKALAEVFQKYTPNIVFHAAAYKHVPLVEENISRAIRNNILGTKNAIDLAIEAGVE
SFILISTDKAVRPTNVMGATKRVCELYLQNVDPKNTKLAAVRFGNVLGSSGSVIPKFEEQIRKGGPVTVTHPEITRYFML
IPEACELVLQAGAIAKNSEVFVLDMGQPVKIIDLAKQFIRLSGRGDIDIKIVGLRPGEKLYEELLIEEDDVSTDYKDIFI
GRRTFYDINTLNQDIESLIKDDVDQLVILKKIVPEFEHRLNG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cap1D AAA64643.1 type 1 capsule synthesis gene Virulence SCCcap1 Protein 4e-75 44
SSP0063 YP_300153.1 capsular polysaccharide biosynthesis protein Not tested SCC15305cap Protein 1e-70 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
wbtA YP_005306071.1 UDP-N-acetylglucosamine 4 6-dehydratase VFG1300 Protein 3e-74 42