Gene Information

Name : RSA_00335 (RSA_00335)
Accession : YP_005300136.1
Strain : Rickettsia philipii 364D
Genome accession: NC_016930
Putative virulence/resistance : Virulence
Product : chaperone ClpB
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 50660 - 53233 bp
Length : 2574 bp
Strand : +
Note : COG0542 ATPases with chaperone activity, ATP-binding subunit

DNA sequence :
ATGAATATTGATAAATTTACTGCACATGCTAAATCATTGATAGCTAGTAGCCAATCACTTGCTGCTAAAAATGATCATCA
GCAAATATTACCTTTGCATTTATTATCTAGTCTTTTAAGTGAAGAAACAGGTATAATTCAAACCCTTATTAATAATACTG
GCGGTAATATAAACTTATTAAAAGATCAAGTTCAGCTAGAACTAAATAAAATCCCAAAAGTTCAGGTTGAGGGAGGAGGA
CAAGTTTATTCTTCTGCTGAAGCTTTTAAAGTTTTAGAAAAAGCTAGTAGCATTGCTAAAGACAGTGGGGATAGCTTTGT
AACCATAGAGCGTATATTTGAAGCATTAACTTATGATAATACTATAGCCGGTAAAATTTTAACGAATAATGGAATTAATA
ATAAAAAAATAGCAACAGCTATTTTACAGTTTCGTAAAGGCAAAAAAGCAGATACCGAATCGGCAGAAAATAGTTATGAT
GCTTTAAAGAAATACGGCAGAGACGTAACAGAGCTTGCAGAAAGCGGTAAGCTTGATCCGATCATCGGACGTGATGAAGA
AATAAGAAGAACGGTGCAGGTACTATCACGACGTATGAAAAATAATCCTGTATTGATTGGAGAACCTGGAGTTGGTAAAA
CTGCTATAATAGAGGGGCTTGCACAACGAATATTTAGTAAGGACGTACCTGAATCGCTTATTAATTGCCGTATTATTGAG
CTTGATATGGGAGCTTTAATAGCGGGAGCTAAATATCGAGGCGAATTTGAAGAGCGTCTTAAAGCAGTGCTTAGCGAAAT
CAAAGAATCAAGCGGTGAAATTATTTTATTTATCGATGAATTGCATCTATTAGTCGGTACGGGAAAAACCGACGGTGTTA
TGGATGCCTCGAATTTACTAAAGCCGATGCTTGCTCGTGGTGAGCTGCATTGTATCGGTGCTACTACGCTAGATGAATAT
CGTAAATATATCGAGAAAGATGCAGCACTTGCTCGTCGTTTTCAGCCTGTTTACGTGAGTGAGCCGACGGTTGAGGATAC
TATATCAATACTTAGAGGAATTAAAGAAAAATATGAGCTGCATCATGCAGTGCGAATTTCCGATAGTGCAATAGTTGCAG
CAGCGACGTTATCAAACCGTTATATTACCGATCGTTATTTACCTGATAAAGCTATTGATTTGATTGATGAAGCTTGTAGC
CGTATGAAAATAGAGCTATCAAGTAAACCAGAAGAGCTTGATGAGCTGGACCGTCGTATTGTTCAGATAAAAATAGAGCT
TGCAGCACTTAAAAAAGAAAATGACGAGCATTCTAAAAAGAAAATAGAGCATTTAACTACAGCATTAGAAAAATTAGAGT
CTAAATCCTATGATATGGGAGCTAAATGGCAAGCTGAAAAGTCTAAACTACAGCAAACACAAAAGCTCAAAGAAGAACTA
GACCGTAGCCGAAACGAGCTTGAACGTGCCGAACGTGATGCTAATCTCGCTAAAGCTAGTGAGCTAAAATACGGAATTAT
ACCTGAGATTATGAAAAAGATTCAGGAAGCCGAAAGTATGGATAATAAAGGGCTGTTAAAAGAAATTGTATCGGAAAGTG
ATATAGCAAGTATTATCTCTCGTATTACTGGTATTCCAATTGATACGATGCTATCAAGTGAACGTGAGCGTCTGCTTGTG
ATGGAGCAGAAATTACGAGAATCGGTAATAGGCCAGGATAAGGCAATTAAAGGTGTTAGTGATGCGGTAAGAAGATCACG
TGCAGGGATTCAAGATATTAACCGCCCGCTTGGTTCGTTCTTATTCTTAGGACCGACCGGAGTCGGTAAAACCGAGCTTA
CCAAAGCCTTAGCTGGTTTTCTTTTTGATGACCGTAATGCAATACTTCGTATAGATATGTCGGAATATATGGAGAAGCAC
GCTATTTCTCGCTTGATAGGAGCTCCTCCCGGCTATATCGGATATGATCAAGGCGGAGTGTTAACGGAGGCAGTAAGACG
TCGTCCTTATCAGGTAATATTATTTGATGAGGTTGAAAAAGCCCATCCCGACATATTTAATATTATGCTGCAAATACTTG
ATGAGGGAAGATTAACAGATAGTCAAGGTATAACAGTTGATTTTAAGAATACTATAATAGTTTTAACGTCTAATTTAGGT
GCTGAGATACTCGTTAATCAGAAAAAGGACGAAGATACATATAAAGTAAAGGATGAGGTTATGGAATATGTAAAAGCAGT
ATTTAAACCTGAGTTTTTAAACAGATTAGACGAGATTATATTATTCCATCGCCTAAATCGTAATAATATTCATGATATAG
TTAAGATACAGCTTGAAAGTTTAAAGAAAATTTTACTAGCACAAAATATTATTCTTGAATTTGATGAATCTGCATTAAAT
TATTTAGCCGAAAAAGGTTATGATCCAAGCTTTGGAGCAAGACCATTAAAACGTCTTATCCAGCGGGAAATACAAAATAA
TTTAGCCAAAATGATTTTAGCAGGCGAAATAAGTAGCGGTAAAACGGTTAAAATAAATGCAAAGGATAAAGAATTGAAGG
TAACAATAAGTTGA

Protein sequence :
MNIDKFTAHAKSLIASSQSLAAKNDHQQILPLHLLSSLLSEETGIIQTLINNTGGNINLLKDQVQLELNKIPKVQVEGGG
QVYSSAEAFKVLEKASSIAKDSGDSFVTIERIFEALTYDNTIAGKILTNNGINNKKIATAILQFRKGKKADTESAENSYD
ALKKYGRDVTELAESGKLDPIIGRDEEIRRTVQVLSRRMKNNPVLIGEPGVGKTAIIEGLAQRIFSKDVPESLINCRIIE
LDMGALIAGAKYRGEFEERLKAVLSEIKESSGEIILFIDELHLLVGTGKTDGVMDASNLLKPMLARGELHCIGATTLDEY
RKYIEKDAALARRFQPVYVSEPTVEDTISILRGIKEKYELHHAVRISDSAIVAAATLSNRYITDRYLPDKAIDLIDEACS
RMKIELSSKPEELDELDRRIVQIKIELAALKKENDEHSKKKIEHLTTALEKLESKSYDMGAKWQAEKSKLQQTQKLKEEL
DRSRNELERAERDANLAKASELKYGIIPEIMKKIQEAESMDNKGLLKEIVSESDIASIISRITGIPIDTMLSSERERLLV
MEQKLRESVIGQDKAIKGVSDAVRRSRAGIQDINRPLGSFLFLGPTGVGKTELTKALAGFLFDDRNAILRIDMSEYMEKH
AISRLIGAPPGYIGYDQGGVLTEAVRRRPYQVILFDEVEKAHPDIFNIMLQILDEGRLTDSQGITVDFKNTIIVLTSNLG
AEILVNQKKDEDTYKVKDEVMEYVKAVFKPEFLNRLDEIILFHRLNRNNIHDIVKIQLESLKKILLAQNIILEFDESALN
YLAEKGYDPSFGARPLKRLIQREIQNNLAKMILAGEISSGKTVKINAKDKELKVTIS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 3e-159 48

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
RSA_00335 YP_005300136.1 chaperone ClpB VFG0079 Protein 8e-161 46
RSA_00335 YP_005300136.1 chaperone ClpB VFG2084 Protein 3e-104 41