Gene Information

Name : RPK_00335 (RPK_00335)
Accession : YP_005294793.1
Strain : Rickettsia rickettsii Hlp#2
Genome accession: NC_016915
Putative virulence/resistance : Virulence
Product : chaperone ClpB
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 52605 - 55178 bp
Length : 2574 bp
Strand : +
Note : COG0542 ATPases with chaperone activity, ATP-binding subunit

DNA sequence :
ATGAATATTGATAAATTTACTGCACATGCTAAATCATTGATAGCTAGTAGCCAATCACTTGCTGCTAAAAATGATCATCA
GCAAATATTACCTTTGCATTTATTATCTAGTCTTTTAAGTGAAGAAACAGGTATAATTCAAACCCTTATTAATAATACCG
GCGGTAATATAAACTTATTAAAAGATCAAGTTCAGCTAGAACTAAATAAAATCCCAAAAGTTCAGGTTGAGGGAGGAGGA
CAAGTTTATTCTTCTGCTGAAGCTTTTAAAGTTTTAGAAAAAGCTAGTAGCATTGCTAAAGACAGTGGGGATAGCTTTGT
AACCATAGAGCGTATATTTGAAGCATTAACTTATGATAATACTATAGCCGGTAAAATTTTAACGAATAATGGAATTAATA
ATAAAAAAATAGCAACAGCTATTTTACAGTTTCGTAAAGGCAAAAAAGCAGATACCGAATCGGCAGAAAATAGTTATGAT
GCTTTAAAGAAATACGGCAGAGACGTAACAGAGTTTGCCGAAAGCGGTAAGCTTGATCCGATCATCGGACGTGATGAAGA
AATAAGAAGAACGGTGCAGGTACTATCACGACGTATGAAAAATAATCCTGTATTGATTGGAGAACCTGGAGTTGGTAAAA
CTGCTATAATAGAGGGGCTTGCACAACGAATATTTAGTAAGGACGTACCTGAATCGCTTATTAATTGCCGTATTATTGAG
CTTGATATGGGAGCTTTAATAGCGGGAGCTAAATATCGAGGCGAATTTGAAGAGCGTCTTAAAGCAGTGCTTAGCGAAAT
CAAAGAATCAAGCGGTGAAATTATTTTATTTATCGATGAATTGCATCTATTAGTCGGTACGGGAAAAACCGACGGTGTTA
TGGATGCCTCGAATTTACTAAAGCCTATGCTTGCTCGTGGTGAGCTGCATTGTATCGGTGCTACTACTCTAGATGAATAT
CGTAAATATATCGAGAAAGATGCGGCACTTGCTCGTCGTTTTCAGCCTGTTTACGTGAGTGAGCCGACGGTTGAGGATAC
TATATCAATACTTAGAGGAATTAAAGAAAAATATGAGCTGCATCATGCAGTGCGAATTTCCGATAGTGCAATAGTTGCAG
CAGCGACGTTATCAAACCGTTATATTACCGATCGTTATTTACCTGATAAAGCTATTGATTTGATTGATGAAGCTTGTAGC
CGTATGAAAATAGAGCTATCAAGTAAACCAGAAGAGCTTGATGAGCTGGACCGTCGTATTATTCAGATAAAAATAGAGCT
TGCAGCACTTAAAAAAGAAAATGACGAGCATTCTAAAAAGAAAATAGAGCATTTAACTAAAGCATTAGAAAAATTAGAGT
CTAAATCCTATGATATGGGAGCTAAATGGCAAGCTGAAAAGTCTAAACTACAGCAAACACAAAAGCTCAAAGAAGAACTA
GACCGTAGCCGAAACGAGCTTGAACGTGCCGAACGTGATGCTAATCTCGCTAAAGCTAGTGAGCTAAAATACGGAATTAT
ACCTGAGATTATGAAAAAGATTCAGGAAGCCGAAAGTATTGATAATAAAGGGCTGTTAAAAGAAATTGTATCGGAAAGTG
ATATAGCAAGTATTATCTCTCGTATTACTGGTATTCCAATTGATACGATGCTATCAAGTGAACGTGAGCGTCTGCTTGTG
ATGGAGCAGAAATTACGAGAATCGGTAATAGGCCAGGATAAGGCAATTAAAGGTGTTAGTGATGCGGTAAGAAGATCACG
TGCAGGGATTCAAGATATTAACCGCCCGCTTGGTTCGTTCTTATTCTTAGGACCGACCGGAGTCGGTAAAACCGAGCTTA
CCAAAGCCTTAGCTGGTTTTCTTTTTGATGACCGTAATGCAATACTTCGTATAGATATGTCGGAATATATGGAGAAGCAC
GCTATTTCTCGCTTGATAGGAGCTCCTCCCGGCTATATCGGATATGATCAAGGCGGAGTGTTAACGGAGGCAGTAAGACG
TCGTCCTTATCAGGTAATATTATTTGATGAGGTTGAAAAAGCCCATCCCGACATATTTAATATTATGCTGCAAATACTTG
ATGAGGGAAGATTAACAGATAGTCAAGGTATAACAGTTGATTTTAAGAATACTATAATAGTTTTAACGTCTAATTTAGGT
GCTGAGATACTCGTTAATCAGAAAAAGGACGAAGATACATATAAAGTAAAGGATGAGGTTATGGAATATGTAAAAGCAGT
ATTTAAACCTGAGTTTTTAAACAGATTAGACGAGATTATATTATTCCATCGCCTAAATCGTAATAATATTTATGATATAG
TTAAGATACAGCTTGAAAGTTTAAAGAAAATTTTACTAGCACAAAATATTATTCTTGAATTTGATGAATCTGCATTAAAT
TATTTAGCCGAAAAAGGTTATGATCCAAGCTTTGGAGCAAGACCATTAAAACGTCTTATCCAGCGGGAAATACAAAATAA
TTTAGCCAAAATGATTTTAGCAGGCGAAATAAGTAGCGGTAAAACGGTTAAAATAAATGCAAAGGATAAAGAATTGAAGG
TAACAATAAGTTGA

Protein sequence :
MNIDKFTAHAKSLIASSQSLAAKNDHQQILPLHLLSSLLSEETGIIQTLINNTGGNINLLKDQVQLELNKIPKVQVEGGG
QVYSSAEAFKVLEKASSIAKDSGDSFVTIERIFEALTYDNTIAGKILTNNGINNKKIATAILQFRKGKKADTESAENSYD
ALKKYGRDVTEFAESGKLDPIIGRDEEIRRTVQVLSRRMKNNPVLIGEPGVGKTAIIEGLAQRIFSKDVPESLINCRIIE
LDMGALIAGAKYRGEFEERLKAVLSEIKESSGEIILFIDELHLLVGTGKTDGVMDASNLLKPMLARGELHCIGATTLDEY
RKYIEKDAALARRFQPVYVSEPTVEDTISILRGIKEKYELHHAVRISDSAIVAAATLSNRYITDRYLPDKAIDLIDEACS
RMKIELSSKPEELDELDRRIIQIKIELAALKKENDEHSKKKIEHLTKALEKLESKSYDMGAKWQAEKSKLQQTQKLKEEL
DRSRNELERAERDANLAKASELKYGIIPEIMKKIQEAESIDNKGLLKEIVSESDIASIISRITGIPIDTMLSSERERLLV
MEQKLRESVIGQDKAIKGVSDAVRRSRAGIQDINRPLGSFLFLGPTGVGKTELTKALAGFLFDDRNAILRIDMSEYMEKH
AISRLIGAPPGYIGYDQGGVLTEAVRRRPYQVILFDEVEKAHPDIFNIMLQILDEGRLTDSQGITVDFKNTIIVLTSNLG
AEILVNQKKDEDTYKVKDEVMEYVKAVFKPEFLNRLDEIILFHRLNRNNIYDIVKIQLESLKKILLAQNIILEFDESALN
YLAEKGYDPSFGARPLKRLIQREIQNNLAKMILAGEISSGKTVKINAKDKELKVTIS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 8e-159 48

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
RPK_00335 YP_005294793.1 chaperone ClpB VFG0079 Protein 4e-160 46
RPK_00335 YP_005294793.1 chaperone ClpB VFG2084 Protein 4e-104 41