Gene Information

Name : guaA (SAVC_01705)
Accession : YP_005289941.1
Strain : Staphylococcus aureus VC40
Genome accession: NC_016912
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : -
COG ID : -
EC number : 6.3.5.2
Position : 381702 - 383243 bp
Length : 1542 bp
Strand : +
Note : COG0518 GMP synthase - Glutamine amidotransferase domain

DNA sequence :
ATGGAAATGGCAAAAGAACAAGAGTTAATCCTTGTCTTAGACTTTGGTAGCCAATACAACCAATTAATTACACGCCGAAT
TCGTGAAATGGGCGTTTATAGTGAATTACACGATCATGAAATTTCAATTGAAGAAATTAAGAAAATGAATCCAAAAGGTA
TTATCTTATCAGGTGGTCCAAATTCAGTTTATGAAGAAGGTTCATTTACAATTGATCCGGAAATATATAATTTAGGAATT
CCAGTACTTGGTATTTGTTACGGCATGCAATTAACTACTAAATTATTAGGTGGTAAAGTTGAACGTGCCAATGAACGTGA
ATACGGTAAAGCAATCATTAATGCGAAGTCAGATGAGTTATTCGCTGGCTTACCAGCAGAACAAACTGTTTGGATGAGTC
ATTCTGATAAAGTTATTGAAATTCCAGAAGGCTTTGAAGTTATCGCTGATAGCCCAAGCACAGACTATGCAGCAATCGAA
GATAAGAAACGTCGCATTTATGGTGTTCAATTCCATCCAGAAGTACGTCATACAGAATATGGTAATGATTTATTAAATAA
TTTTGTCCGTCGTGTTTGTGATTGTAGAGGTCAATGGACAATGGAAAACTTTATCGAAATCGAAATTGAAAAGATTCGTC
AACGCGTAGGAGACCGTCGTGTATTATGTGCGATGAGTGGCGGCGTAGATTCATCTGTTGTAGCTGTACTATTGCATAAA
GCAATAGGTGATCAACTAACATGTATCTTTGTAGACCATGGCTTACTTCGTAAAGGTGAAGGCGACATGGTTATGGAGCA
ATTCGGTGAAGGTTTCAACATGAATATTATTCGTGTTAATGCGAAAGATCGCTTTATGAATAAATTAAAAGGTGTTTCAG
ATCCTGAACAAAAACGTAAAATCATTGGTAATGAATTTGTATACGTATTTGATGATGAAGCATCAAAACTGAAAGGTGTA
GACTTCCTTGCGCAAGGAACACTATATACAGACGTCATCGAATCAGGTACTAAAACAGCACAAACAATCAAATCACACCA
CAATGTTGGTGGATTACCAGAAGACATGGAATTCGAATTAATCGAACCAATCAATACATTGTTTAAAGATGAAGTACGTA
AATTAGGTATTGAGTTAGGTATTCCAGAACATTTAGTATGGAGACAACCATTCCCAGGACCTGGTCTTGGTATTCGTGTA
CTTGGAGAAATTACTGAAGATAAACTAGAAATCGTTAGAGAATCAGACGCGATTTTACGCCAAGTGATTAGAGAAGAAGG
TCTTGAAAGAGAAATTTGGCAATACTTCACAGTGTTACCAAACATTCAATCAGTAGGTGTTATGGGAGACTACCGTACGT
ATGATCACACAGTAGGTATTCGTGCAGTAACATCTATCGACGGTATGACAAGTGACTTCGCACGCATCGATTGGGAAGTC
TTACAAAAGATTTCTAGTCGTATCGTAAACGAAGTAGATCACGTCAACCGCGTAGTCTATGACATTACATCAAAACCACC
AAGCACAATTGAGTGGGAATAA

Protein sequence :
MEMAKEQELILVLDFGSQYNQLITRRIREMGVYSELHDHEISIEEIKKMNPKGIILSGGPNSVYEEGSFTIDPEIYNLGI
PVLGICYGMQLTTKLLGGKVERANEREYGKAIINAKSDELFAGLPAEQTVWMSHSDKVIEIPEGFEVIADSPSTDYAAIE
DKKRRIYGVQFHPEVRHTEYGNDLLNNFVRRVCDCRGQWTMENFIEIEIEKIRQRVGDRRVLCAMSGGVDSSVVAVLLHK
AIGDQLTCIFVDHGLLRKGEGDMVMEQFGEGFNMNIIRVNAKDRFMNKLKGVSDPEQKRKIIGNEFVYVFDDEASKLKGV
DFLAQGTLYTDVIESGTKTAQTIKSHHNVGGLPEDMEFELIEPINTLFKDEVRKLGIELGIPEHLVWRQPFPGPGLGIRV
LGEITEDKLEIVRESDAILRQVIREEGLEREIWQYFTVLPNIQSVGVMGDYRTYDHTVGIRAVTSIDGMTSDFARIDWEV
LQKISSRIVNEVDHVNRVVYDITSKPPSTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 0.0 100
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 0.0 99
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 0.0 99
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-131 51