Gene Information

Name : ureC (SAVC_10310)
Accession : YP_005291648.1
Strain : Staphylococcus aureus VC40
Genome accession: NC_016912
Putative virulence/resistance : Virulence
Product : urease subunit alpha
Function : -
COG functional category : -
COG ID : -
EC number : 3.5.1.5
Position : 2224261 - 2225976 bp
Length : 1716 bp
Strand : +
Note : COG0804 Urea amidohydrolase (urease) alpha subunit

DNA sequence :
ATGAGCTTTAAAATGACGCAAAATCAATATACGAGCTTATACGGTCCAACTGTTGGAGATTCCATTCGTTTAGGTGATAC
GAATCTATTTGCTCAAATAGAAAAAGACTATGCGGTTTATGGTGAAGAAGCTACTTTTGGTGGTGGTAAATCTATTAGAG
ACGGTATGGCGCAAAATCCTCGTGTAACACGTGATGACGTGAACGTTGCAGACCTTGTCATTTCTAATGCCGTTATTATC
GATTACGATAAAGTGGTTAAAGCTGATATAGGCATTAAAAATGGTTATATTTTCGCCATAGGTAATGCCGGCAACCCAGA
TATAATGGATAATGTCGACATTATTATAGGTTCAACAACAGATATCATTGCCGCTGAAGGTAAAATCGTCACTGCTGGTG
GTATTGATACTCATGTTCATTTTATTAATCCTGAACAAGCAGAGGTCGCATTAGAAAGTGGTATTACGACTCATATTGGT
GGTGGTACTGGTGCTTCAGAAGGTTCTAAAGCAACAACTGTAACTCCAGGTCCATGGCATATTCATAGAATGTTAGAAGC
TGCCGAAGGTTTACCGATTAATGTCGGTTTTACAGGTAAAGGACAAGCAACAAATCCAACTGCACTCATTGAACAAATCA
ATGCCGGAGCAATTGGATTAAAAGTACATGAAGACTGGGGTGCAACACCATCTGCTTTGAGTCATGCATTAGATGTTGCT
GATGAATTTGATGTTCAAATTGCATTACATGCAGATACTTTAAATGAAGCAGGATTTATGGAAGACACAATGGCTGCTGT
TAAAGACCGTGTACTTCATATGTACCATACTGAAGGTGCTGGTGGCGGTCATGCGCCTGATTTAATTAAATCCGCTGCAT
TTTCAAATATTTTACCTTCATCTACAAATCCAACTTTGCCTTATACACATAATACTGTAGATGAACATTTAGATATGGTA
ATGATTACTCACCATTTAAATGCGGCTATTCCTGAAGATATCGCATTCGCAGATTCACGTATTCGTAAAGAAACGATTGC
AGCAGAAGATGTTCTGCAAGATATGGGTGTATTCAGTATGATTAGTTCCGATTCACAAGCAATGGGCCGTGTAGGTGAAG
TAATTACACGAACATGGCAAGTAGCACATCGCATGAAAGAACAACGTGGTCCTTTAGATGGTGATTTTGAACATAATGAT
AATAATCGCATCAAACGTTATATCGCTAAATATACAATTAACCCAGCAATTACACATGGTATTTCTGAATATGTAGGATC
TATCGAGCCGGGCAAACTAGCTGACATTGTCTTATGGGACCCAATTTTCTTTGGGGTTAAACCTGAATTAGTTGTAAAGG
GCGGATTAATTAACTCTGCCGTAAATGGCGATGCAAATGGTTCTATACCTACATCTGAACCGATGAAGTACCGTAAAATG
TATGGTCAATACGGCGGAAACCTTACAAGTACGTCAATGACATTCGTGTCTAAAACTGCTTATGAAAATGGTATCAATCG
TGCATTAAATTTAAAACGCATGGTGCGTCCAGTTAAAAATATTAGACAATTATCTAAAGCAGATATGAAAAATAACAGTG
CAACACCTAAATTAGACGTTGATCCACAAACATATGAAGTATATGTAGATGGAGAAAAAATTACAAGTAATGCAGCAACT
GAGTTACCATTAACTCAAAGATACTTCTTATTCTAG

Protein sequence :
MSFKMTQNQYTSLYGPTVGDSIRLGDTNLFAQIEKDYAVYGEEATFGGGKSIRDGMAQNPRVTRDDVNVADLVISNAVII
DYDKVVKADIGIKNGYIFAIGNAGNPDIMDNVDIIIGSTTDIIAAEGKIVTAGGIDTHVHFINPEQAEVALESGITTHIG
GGTGASEGSKATTVTPGPWHIHRMLEAAEGLPINVGFTGKGQATNPTALIEQINAGAIGLKVHEDWGATPSALSHALDVA
DEFDVQIALHADTLNEAGFMEDTMAAVKDRVLHMYHTEGAGGGHAPDLIKSAAFSNILPSSTNPTLPYTHNTVDEHLDMV
MITHHLNAAIPEDIAFADSRIRKETIAAEDVLQDMGVFSMISSDSQAMGRVGEVITRTWQVAHRMKEQRGPLDGDFEHND
NNRIKRYIAKYTINPAITHGISEYVGSIEPGKLADIVLWDPIFFGVKPELVVKGGLINSAVNGDANGSIPTSEPMKYRKM
YGQYGGNLTSTSMTFVSKTAYENGINRALNLKRMVRPVKNIRQLSKADMKNNSATPKLDVDPQTYEVYVDGEKITSNAAT
ELPLTQRYFLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 3e-178 64
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 3e-178 64
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 3e-178 64
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 1e-176 63
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 3e-173 63
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 3e-173 63

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ureC YP_005291648.1 urease subunit alpha VFG0270 Protein 6e-158 58