Gene Information

Name : SAVC_00605 (SAVC_00605)
Accession : YP_005289722.1
Strain : Staphylococcus aureus VC40
Genome accession: NC_016912
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 137266 - 138753 bp
Length : 1488 bp
Strand : +
Note : COG1012 NAD-dependent aldehyde dehydrogenases

DNA sequence :
ATGGCAGTAAACGTTCGAGATTATATTGCAGAGAATTATGGTTTATTTATCAATGGGGAATTTGTTAAAGGTAGCAGTGA
CGAAACAATCGAAGTGACTAATCCAGCAACTGGAGAAACACTATCACATATTACAAGAGCAAAAGATAAAGATGTCGATC
ATGCAGTCAAAGTGGCGCAAGAGGCATTTGAATCATGGTCATTAACTTCTAAATCAGAACGTGCACAAATGTTGCGTGAT
ATTGGTGATAAATTAATGGCACAAAAAGATAAAATTGCAATGATTGAAACATTAAATAATGGTAAACCGATTCGTGAGAC
AACAGCAATTGATATTCCATTTGCTGCAAGACATTTCCATTATTTCGCAAGTGTTATTGAAACAGAAGAAGGTACAGTGA
ATGATATCGATAAAGACACAATGAGTATCGTACGACATGAGCCGATTGGCGTCGTAGGTGCTGTTGTTGCTTGGAACTTC
CCAATGCTATTAGCTGCATGGAAGATTGCGCCAGCCATTGCTGCAGGTAATACAATTGTGATTCAACCTTCGTCTTCAAC
ACCATTAAGTTTATTGGAAGTTGCTAAAATTTTCCAAGAGGTATTACCTAAAGGTGTTGTCAATATACTAACGGGTAAAG
GTTCAGAATCAGGTAATGCAATTTTCAATCATGATGGTGTAGATAAATTATCATTTACGGGCTCAACTGATGTAGGTTAT
CAAGTTGCCGAAGCTGCAGCAAAACATCTAGTACCCGCTACATTAGAGCTTGGTGGTAAAAGCGCCAATATCATATTAGA
TGATGCTAATTTAGACCTTGCAGTTGAAGGTATTCAGTTAGGTATTTTATTCAACCAAGGTGAAGTATGTAGTGCAGGTT
CTCGATTATTAGTTCATGAAAAAATTTATGATCAATTGGTGCCACGTTTACAAGAGGCATTTTCAAATATTAAAGTTGGA
AATCCACAAGATGAAGCTACACAAATGGGTAGTCAAATTGGTAAGGATCAATTAGATAAAATTCAATCATATATTGATGC
AGCAAAAGAATCAGATGCACAAATTTTAGCAGGCGGTCATCGCTTAACTGAAAATGGATTAGATAAAGGGTTCTTCTTTG
AGCCGACATTAATTGCTGTGCCAGACAATCATCACAAATTAGCACAAGAAGAAATATTTGGACCAGTGTTAACAGTGATT
AAAGTGAAGGACGATCAAGAAGCAATTGATATAGCTAATGATTCTGAGTATGGTTTAGCAGGCGGTGTATTTTCTCAAAA
TATCACACGTGCATTAAATATTGCTAAAGCTGTACGTACAGGACGTATTTGGATTAACACTTACAACCAAGTACCAGAAG
GCGCACCATTTGGTGGTTATAAAAAATCAGGTATCGGTCGAGAAACTTATAAAGGTGCGTTAAGTAACTATCAACAAGTT
AAAAATATTTATATTGATACAAGCAATGCTTTAAAAGGTTTGTACTAG

Protein sequence :
MAVNVRDYIAENYGLFINGEFVKGSSDETIEVTNPATGETLSHITRAKDKDVDHAVKVAQEAFESWSLTSKSERAQMLRD
IGDKLMAQKDKIAMIETLNNGKPIRETTAIDIPFAARHFHYFASVIETEEGTVNDIDKDTMSIVRHEPIGVVGAVVAWNF
PMLLAAWKIAPAIAAGNTIVIQPSSSTPLSLLEVAKIFQEVLPKGVVNILTGKGSESGNAIFNHDGVDKLSFTGSTDVGY
QVAEAAAKHLVPATLELGGKSANIILDDANLDLAVEGIQLGILFNQGEVCSAGSRLLVHEKIYDQLVPRLQEAFSNIKVG
NPQDEATQMGSQIGKDQLDKIQSYIDAAKESDAQILAGGHRLTENGLDKGFFFEPTLIAVPDNHHKLAQEEIFGPVLTVI
KVKDDQEAIDIANDSEYGLAGGVFSQNITRALNIAKAVRTGRIWINTYNQVPEGAPFGGYKKSGIGRETYKGALSNYQQV
KNIYIDTSNALKGLY

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-97 45
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 3e-100 45
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 3e-100 45
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 3e-100 45
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 6e-100 45

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SAVC_00605 YP_005289722.1 aldehyde dehydrogenase VFG0082 Protein 6e-98 45