Gene Information

Name : EKO11_3296 (EKO11_3296)
Accession : YP_005278941.1
Strain : Escherichia coli KO11FL
Genome accession: NC_016902
Putative virulence/resistance : Virulence
Product : two component heavy metal response transcriptional regulator, winged helix family
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 3444587 - 3445270 bp
Length : 684 bp
Strand : +
Note : TIGRFAM: heavy metal response regulator; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; KEGG: ebd:ECBD_3091 DNA-binding transcriptional activator CusR; SMART: response regulator receiver

DNA sequence : 
ATGAAACTGTTGATTGTCGAAGATGAAAAGAAAACCGGAGAATACTTGACCAAAGGGTTAACCGAAGCCGGTTTTGTGGT
CGATTTGGCCGACAACGGGCTGAATGGCTACCATCTGGCGATGACCGGTGATTATGATCTGATAATCCTCGATATTATGC
TGCCGGACGTGAACGGCTGGGATATCGTGCGCATGTTACGCTCCGCCAATAAAGGGATGCCGATTCTGTTGCTTACCGCG
CTTGGCACCATTGAACATCGCGTCAAGGGGCTGGAGTTGGGGGCAGATGACTACCTGATGAAACCATTCGCTTTTGCTGA
ACTGCTGGCGCGGGTGCGCACTCTCCTGCGGCGCGGGGCGGCGGTAATTATCGAAAGTCAGTTTCAGGTTGCCGACCTGA
TGGTCGATCTCGTCAGCCGCAAAGTCACCCGCAGCGGCACGCGCATCACTCTGACCAGTAAAGAGTTTACTCTGCTGGAG
TTTTTTCTCCGCCATCAGGGCGAAGTGCTGCCCCGCTCGCTTATCGCCTCGCAGGTGTGGGACATGAATTTCGACAGCGA
CACTAACGCCATTGATGTGGCGGTGAAGCGGCTACGCGGCAAAATCGACAACGACTTTGAGCCGAAGCTGATTCAGACCG
TGCGCGGCGTGGGCTATATGCTTGAGGTGCCGGATGGTCAGTAA

Protein sequence : 
MKLLIVEDEKKTGEYLTKGLTEAGFVVDLADNGLNGYHLAMTGDYDLIILDIMLPDVNGWDIVRMLRSANKGMPILLLTA
LGTIEHRVKGLELGADDYLMKPFAFAELLARVRTLLRRGAAVIIESQFQVADLMVDLVSRKVTRSGTRITLTSKEFTLLE
FFLRHQGEVLPRSLIASQVWDMNFDSDTNAIDVAVKRLRGKIDNDFEPKLIQTVRGVGYMLEVPDGQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
copR NP_460069.2 transcriptional regulatory protein YedW Not tested SPI-5 Protein 6e-56 52
copR AAC33719.1 regulatory protein CopR Not tested SPI-5 Protein 7e-56 52

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
EKO11_3296 YP_005278941.1 two component heavy metal response transcriptional regulator, winged helix family BAC0111 Protein 1e-103 99
EKO11_3296 YP_005278941.1 two component heavy metal response transcriptional regulator, winged helix family BAC0347 Protein 5e-87 82
EKO11_3296 YP_005278941.1 two component heavy metal response transcriptional regulator, winged helix family BAC0638 Protein 3e-63 62
EKO11_3296 YP_005278941.1 two component heavy metal response transcriptional regulator, winged helix family BAC0083 Protein 3e-70 61
EKO11_3296 YP_005278941.1 two component heavy metal response transcriptional regulator, winged helix family BAC0308 Protein 1e-63 60
EKO11_3296 YP_005278941.1 two component heavy metal response transcriptional regulator, winged helix family BAC0197 Protein 2e-63 59
EKO11_3296 YP_005278941.1 two component heavy metal response transcriptional regulator, winged helix family BAC0125 Protein 1e-63 56
EKO11_3296 YP_005278941.1 two component heavy metal response transcriptional regulator, winged helix family AE000516.2.gene3505. Protein 6e-28 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
EKO11_3296 YP_005278941.1 two component heavy metal response transcriptional regulator, winged helix family VFG0596 Protein 2e-56 52
EKO11_3296 YP_005278941.1 two component heavy metal response transcriptional regulator, winged helix family VFG1390 Protein 3e-43 43