Gene Information

Name : clpB (NOCYR_5248)
Accession : YP_005266628.1
Strain : Nocardia cyriacigeorgica GUH-2
Genome accession: NC_016887
Putative virulence/resistance : Virulence
Product : protein disaggregation chaperone
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 5834576 - 5837131 bp
Length : 2556 bp
Strand : -
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 17259993; Product type f : factor

DNA sequence :
GTGGACTCGTTCAATCCCACCACCAAGACCCAAGCGGCGCTGACCGCTGCCTTGCAGGCGGCCTCGGCCGCGGGCAACCC
GGAGATTCGTCCGGCGCACTTGCTGGTGGCGTTGCTGGATCAGACCGACGGCATCGCCGCCCCCTTGCTGAAGGCCGTCG
GTACGGATCCGGCGGTCGTACGACGCGAGGCGCAAGAGATCATCGACCGGTTGCCCAGCGCGACCGGCGCCACCACCACC
CCCCAGCTCGGCCGCGAAGCGCTGGCCGCGATCACCGCGGCGCAGCGGCTGGCCACCGAGATGGGCGATGAGTACGTGTC
CACCGAGCACGTCATGGTCGGCCTGGCCGAAGGCGACTCCGACATCACCATGCTGCTCACCAAATACGGCGCCACCGCCG
ACGCCCTGCGCGCGGCGTTCACCGCCGTGCGCGGCAGCGCCCGGGTCACCAACCCGGATCCCGAAGGCAGCTACCAGGCG
CTGGAGAAGTACTCCACCGACCTCACCGAGGCCGCCCGCTCCGGCAAGCTCGACCCGGTGATCGGCCGCGATACCGAGAT
CCGGCGCGTGGTGCAGGTGCTGTCGCGGCGCACCAAGAACAACCCGGTGCTGATCGGTGAGCCAGGCGTCGGTAAGACCG
CCATCGTCGAGGGGCTGGCCCAGCGCATCGTCGCGGGTGACGTCCCCGAATCGCTGCGCGGCAAGTCGGTCATCTCGCTC
GATATGGGTGCCATGGTGGCCGGTGCGAAGTACCGCGGTGAATTCGAGGAGCGGCTCAAGGCCGTGCTCGAAGACATCAA
GAACAGCGCCGGGCAGATCATCACCTTCATCGACGAGCTGCACACCATCGTCGGTGCGGGCGCCACCGGTGAATCGGCGA
TGGACGCGGGCAACATGATCAAGCCGATGCTGGCCCGCGGCGAGCTGCGCCTGGTCGGCGCCACCACGCTGGAGGAGTAC
CGCCAGCACATCGAGAAGGACGCCGCGCTCGAGCGCCGGTTCCAGCAGGTGCTCGTCGGTGAGCCCTCGGTCGAGGACAC
CGTCGGCATCCTGCGCGGCATCAAGGAGCGCTACGAGGTGCACCACGGTGTGCGCATCACCGACTCCGCGCTGGTCGCCG
CGGCCACCCTGTCCGACCGCTACATCACCTCCCGGTTCCTGCCGGACAAGGCGATCGACCTGGTCGACGAATCGGCCTCG
CGGCTGCGCATGGAGATCGACTCGCGGCCGGTGGAGATCGACGAGGTCGAACGCGCGGTGCGCAGGCTAGAGATCGAAGA
GGTCGCCCTCGCCAAGGAAACCGACGAGGCGTCCAAACAACGGCTGGAGAAGCTGCGCTCGGAACTGGCCGACGACCGGG
AAAAGCTCAACCAGCTCACCACCCGCTGGCAGAACGAGAAGAACGCCATCGACCAGGTCCGCGCGCTCAAGGAGGAACTG
GAATCGCTGCGCGGGGCCTCCGAACGGGCCGAACGCGACGGCGATCTCGGCAAGGCCGCCGAACTGCGCTACGGCAAGAT
CCCCACGCTGGAAAAGCAGCTCGCCGAGGCCGAGAAGGCGTCCGCGTCGGCCGGTGACGGCGAGGTGATGCTGAAGGAAG
AGGTCGGGCCCGACGATATCGCCGAGGTGGTGTCGTCGTGGACCGGTATTCCGGTGGGCCGCATGCTCGAGGGCGAGACT
CAGAAGTTGCTGCGCATGGAGTCCGAACTCGGGCGGCGCGTGGTCGGCCAGGACGAGGCCGTGCGGGCGGTGTCGGATGC
GGTGCGCCGGGCGCGGGCCGGTGTCGCCGACCCGAACCGGCCGACCGGCTCGTTCATGTTCGTCGGCCCCACCGGCGTCG
GTAAGACCGAGCTGGCCAAGGCGCTGGCCGACTTCCTCTTCGACGACGAACGCGCCATGGTCCGCATCGACATGAGCGAG
TACAGCGAGAAGCATTCGGTGGCCCGGTTGGTCGGCGCGCCGCCCGGATACGTCGGCTACGACCAGGGCGGTCAGCTCAC
CGAGGCGGTGCGGCGCAGGCCCTACACCGTGGTGCTGTTCGACGAGATCGAGAAGGCGCATCCGGATGTGTTCGACATCC
TGCTCGCCGTCCTCGACGAGGGCAGGTTGACCGACGGCCAGGGCCGCACCGTCGATTTCCGCAACACCATCCTCATCCTC
ACCTCCAACCTGGGTGCGGGTGGCGACAAGGACTTCGTGATGAACGCCGTGCGCTCGGCCTTCAAACCGGAGTTCCTCAA
CCGGCTCGACGACGTCGTGATGTTCCATTCGCTCAACGAGGAACAGCTCGAGTCCATCGTCGACATCCAGCTCGACCAGC
TGCAGAAGCGGCTGTCGCAGCGCAGGCTGACGCTGGACGTCAGCGGTTCGGCGCGGTTCTGGCTGGCGGTGCGCGGCTAC
GACCCGGTCTACGGTGCGCGGCCACTGCGCAGGCTGATCCAGCAGGCCATCGGCGACACCCTCGCCAAGGAACTGCTCGC
CGGCGAGATCACCGACGGCGACACCGTCAAGGTCGGCGTCAGTCCCGATGGTGACGGGCTCGTCGTCGGCAGGTGA

Protein sequence :
MDSFNPTTKTQAALTAALQAASAAGNPEIRPAHLLVALLDQTDGIAAPLLKAVGTDPAVVRREAQEIIDRLPSATGATTT
PQLGREALAAITAAQRLATEMGDEYVSTEHVMVGLAEGDSDITMLLTKYGATADALRAAFTAVRGSARVTNPDPEGSYQA
LEKYSTDLTEAARSGKLDPVIGRDTEIRRVVQVLSRRTKNNPVLIGEPGVGKTAIVEGLAQRIVAGDVPESLRGKSVISL
DMGAMVAGAKYRGEFEERLKAVLEDIKNSAGQIITFIDELHTIVGAGATGESAMDAGNMIKPMLARGELRLVGATTLEEY
RQHIEKDAALERRFQQVLVGEPSVEDTVGILRGIKERYEVHHGVRITDSALVAAATLSDRYITSRFLPDKAIDLVDESAS
RLRMEIDSRPVEIDEVERAVRRLEIEEVALAKETDEASKQRLEKLRSELADDREKLNQLTTRWQNEKNAIDQVRALKEEL
ESLRGASERAERDGDLGKAAELRYGKIPTLEKQLAEAEKASASAGDGEVMLKEEVGPDDIAEVVSSWTGIPVGRMLEGET
QKLLRMESELGRRVVGQDEAVRAVSDAVRRARAGVADPNRPTGSFMFVGPTGVGKTELAKALADFLFDDERAMVRIDMSE
YSEKHSVARLVGAPPGYVGYDQGGQLTEAVRRRPYTVVLFDEIEKAHPDVFDILLAVLDEGRLTDGQGRTVDFRNTILIL
TSNLGAGGDKDFVMNAVRSAFKPEFLNRLDDVVMFHSLNEEQLESIVDIQLDQLQKRLSQRRLTLDVSGSARFWLAVRGY
DPVYGARPLRRLIQQAIGDTLAKELLAGEITDGDTVKVGVSPDGDGLVVGR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 3e-101 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpB YP_005266628.1 protein disaggregation chaperone VFG2076 Protein 5e-117 44
clpB YP_005266628.1 protein disaggregation chaperone VFG2084 Protein 2e-112 42