Gene Information

Name : metB (NOCYR_4608)
Accession : YP_005265997.1
Strain : Nocardia cyriacigeorgica GUH-2
Genome accession: NC_016887
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 5072837 - 5073979 bp
Length : 1143 bp
Strand : -
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 3307782, 6361020; Product type e : enzyme

DNA sequence :
ATGAGTGAGCTGGGATTCTCCACCAGGGCCGTGCACGCCGGTTTCGATCCCGATCCCCAGACCGGCGCGGTGAACGTGCC
CATCTACGCAAGCTCCACCTTCGCCCAGGACGGCGTCGGCGGCCTGCGGGACGGCTACGAATACGGCCGCACCGGCAACC
CGACCCGCACCGCGCTGGAAGCCAACCTGGCCGCGCTGGAATCGGGCCGCTACGGCCGGGCCTTCGCCTCCGGTATGGCC
GCCACCGACTGCGCCCTGCGCGCCACCCTGCGCCCCGGCGACCACATCGTCATCCCCGACGACGCCTACGGCGGCACCTT
CCGGCTCATCGACAAGGTGTTCAGCCAGTGGGGCATCGAGCACTCGCCGGCGCACGTGTTCAACGTCGACGAGATGCGCG
CCGCGATCCGCCCGAACACCAAGCTGGTGTGGATCGAGACCCCCACCAACCCGCTGCTCAGCATCGGTGACATCCCCGCG
CTCGCCGACGTGGCGCACGCCGCAGGCGCCAAGCTGGTGGTCGACAACACCTTCGCCACCCCGTACCTGCAACAGCCGCT
GCTGCTGGGCGCCGACATCGTGGTGCATTCGACCACCAAGTACCTGGGCGGCCACTCCGACGTCATCGGTGGCGCGCTGA
TCACCAACGACGCCGAACTCGACGCCGCGTTCGCGTTCCTGCAGAACGGCGCGGGCGCGGTCCCCGGCCCGTTCGACGCC
TTCCTCACCATGCGCGGCACCAAGACCCTGGCGCTGCGGATGGACCGGCACTGCGACAACGCCGAGACCCTGGCCGAGTT
CCTGACCCGGCACCCGAAGATCTCCCAGGTCATCTACCCCGGCCTGAACGAGCACCCCGGACACGCCGTCGCCGACAAGC
AGATGCGCCGCTTCGGCGGCATGATCTCGGTGCGCCTGAACGACGGCCCCGACGCCGCCCGCGACGTCTGCTCCCGCACC
AAGATCTTCACCCTGGCCGAATCGCTGGGCGGGGTGGAATCGCTGATCGAGCATCCGGCGGCCATGACCCACGCGTCCAC
CGCGGGGTCGATGCTGGAGGTGCCCGCCGATCTGGTGCGACTGTCGGTCGGCATCGAGGACGTCAGCGATCTGCTCGCCG
ACCTCGAGCAGGCGCTGAGCTGA

Protein sequence :
MSELGFSTRAVHAGFDPDPQTGAVNVPIYASSTFAQDGVGGLRDGYEYGRTGNPTRTALEANLAALESGRYGRAFASGMA
ATDCALRATLRPGDHIVIPDDAYGGTFRLIDKVFSQWGIEHSPAHVFNVDEMRAAIRPNTKLVWIETPTNPLLSIGDIPA
LADVAHAAGAKLVVDNTFATPYLQQPLLLGADIVVHSTTKYLGGHSDVIGGALITNDAELDAAFAFLQNGAGAVPGPFDA
FLTMRGTKTLALRMDRHCDNAETLAEFLTRHPKISQVIYPGLNEHPGHAVADKQMRRFGGMISVRLNDGPDAARDVCSRT
KIFTLAESLGGVESLIEHPAAMTHASTAGSMLEVPADLVRLSVGIEDVSDLLADLEQALS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-75 47
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-76 47
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 3e-60 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
metB YP_005265997.1 cystathionine gamma-synthase BAC0207 Protein 5e-72 44