Gene Information

Name : aldB (NOCYR_4581)
Accession : YP_005265970.1
Strain : Nocardia cyriacigeorgica GUH-2
Genome accession: NC_016887
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 5042219 - 5043736 bp
Length : 1518 bp
Strand : -
Note : Evidence 2b : Function of strongly homologous gene; Product type e : enzyme

DNA sequence :
ATGACCTACGCGAAACCAGGTGCCGAGGGCAGCATCGTCAGCTACGCCGCCCGCTATGACAATTTCATCGGCGGCGACTG
GACGGCACCGGTCGAGGGACAGTACTTCGAGAACCCGTCGCCGGTGGACGGCCAGACCTTCACCGAGGTGGCGCGCTCGA
CCGCCGCCGACGTCGAACTCGCACTCGATGCCGCGCACACCGCCGCCGACGGCTGGGGCGCCACCTCCGCGGCCGAACGC
GCCAATATCCTCAACAAGATCGCCGACCGGATGGAGGACAACCTCGAGGCCCTCGCCGTCGCCGAGACCTGGGAGAACGG
CAAGCCGGTCCGCGAAACCAAGGCCGCCGACCTGCCGCTGGCCATCGACCACTTCCGCTACTTCGCCGGTGCCATCCGCG
CCCAAGAGGGCGGGATCAGCGAGATCGACGGCGACACCATCGCCTACCACTTCCACGAACCGCTCGGCGTGGTCGGTCAG
ATCATCCCGTGGAACTTCCCGATCCTGATGGCAACTTGGAAGCTGGCGCCCGCGCTGGCGGCGGGCAACGCGGTGGTGCT
CAAGCCCGCCGAGCAGACCCCGGCCTCGATCCTGAAGGTGGTGGAGCTGATCGCGGATCTGCTGCCGCCGGGAGTTCTCA
ACGTGGTCAACGGTTTCGGTGTGGAAGCCGGTAAGCCGCTGGCGTCCAGCCCGCGGGTGGCGAAGGTGGCCTTCACCGGC
GAGACCACCACCGGGCGGCTGATCATGCAGTACGCCAGCGAGAACATCATCCCGGTGACGCTGGAGCTGGGCGGTAAGAG
CCCCAACATCTTCCTGCCCGACGTCATGGCCGCCGACGACGAGTTCCTGGACAAGGCCGTCGAAGGCTTCGTGATGTTCG
CGCTGAACCAGGGCGAGGTGTGCACCTGTCCCTCGCGGGCGCTGATCCACTCCTCGATCTACGACGAGTTCATGGCGCGG
TGTATCGAACGCACCAAGGCCATCGTCAGCGGCAACCCGCTCGACGACGCCACCATGATCGGCGCCCAGGCCAGCAACGA
CCAGTACGAGAAGATCCTGTCCTACATCGACATCGGCCGCCAGGAGGGTGCGGAGGTGCTCACCGGCGGTGGGCCGCGCA
AGGTCGAGGAATTCCCGGACGGGTACTACATCGAGCCGACGGTGTTCAAGGGCAGCAACGATATGCGGATCTTCCAGGAG
GAGATCTTCGGCCCGGTGGTGTCGGTGACGACCTTCGATTCCACCGACGAGGCGTTGAAGCTGGCCAACGACACCCTCTA
CGGTCTCGGCGCCGGCGTGTGGACGCGGGATATGAACAGCGCCTACCGGCTGGGTCGCGGGATCAAGGCGGGCCGGGTGT
GGACCAACTGCTACCACGCCTACCCGGCGCACGCGGCGTTCGGCGGATACAAGAAGTCGGGTATCGGCCGCGAGAATCAC
TCGATGATGCTCGACCACTACCAGCAGACCAAGAACCTGCTGGTCAGCTACGCGCCGAATAAGCTCGGATTCTTCTGA

Protein sequence :
MTYAKPGAEGSIVSYAARYDNFIGGDWTAPVEGQYFENPSPVDGQTFTEVARSTAADVELALDAAHTAADGWGATSAAER
ANILNKIADRMEDNLEALAVAETWENGKPVRETKAADLPLAIDHFRYFAGAIRAQEGGISEIDGDTIAYHFHEPLGVVGQ
IIPWNFPILMATWKLAPALAAGNAVVLKPAEQTPASILKVVELIADLLPPGVLNVVNGFGVEAGKPLASSPRVAKVAFTG
ETTTGRLIMQYASENIIPVTLELGGKSPNIFLPDVMAADDEFLDKAVEGFVMFALNQGEVCTCPSRALIHSSIYDEFMAR
CIERTKAIVSGNPLDDATMIGAQASNDQYEKILSYIDIGRQEGAEVLTGGGPRKVEEFPDGYYIEPTVFKGSNDMRIFQE
EIFGPVVSVTTFDSTDEALKLANDTLYGLGAGVWTRDMNSAYRLGRGIKAGRVWTNCYHAYPAHAAFGGYKKSGIGRENH
SMMLDHYQQTKNLLVSYAPNKLGFF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 3e-156 64
aldA ACK75577.1 aldehyde dehydrogenase Not tested VPI Protein 1e-110 63
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 3e-164 63
aldA ACK75585.1 aldehyde dehydrogenase Not tested VPI Protein 4e-110 63
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 3e-164 63
aldA ACK75593.1 aldehyde dehydrogenase Not tested VPI Protein 4e-110 63
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 3e-164 63
aldA ACK75574.1 aldehyde dehydrogenase Not tested VPI Protein 2e-110 63
aldA ACK75590.1 aldehyde dehydrogenase Not tested VPI Protein 2e-110 63
aldA ACK75596.1 aldehyde dehydrogenase Not tested VPI Protein 2e-110 63
aldA ACK75582.1 aldehyde dehydrogenase Not tested VPI Protein 1e-110 63
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-163 63
aldA ACK75588.1 aldehyde dehydrogenase Not tested VPI Protein 1e-110 62
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 1e-73 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
aldB YP_005265970.1 aldehyde dehydrogenase VFG0082 Protein 1e-156 64