Gene Information

Name : clpC (NOCYR_2248)
Accession : YP_005263661.1
Strain : Nocardia cyriacigeorgica GUH-2
Genome accession: NC_016887
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease ATP-binding subunit clpC
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2489042 - 2491501 bp
Length : 2460 bp
Strand : +
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 14640692; Product type f : factor

DNA sequence :
ATGACCGAGTCCTGGCCCAGTTCGATGAGCTCCTTCGACGACATCTTCCAGCGCTTCTTCGGACCCGGAATGTCGGCGCG
GCCGCCGGTGCAGCGCACCGACCTGGGCCGGCTGCTCAGCGATAACGCCAAACAACTCGTCGCCACCGCACAAGCCGCGG
CCAAGGACTGGCGCAGCCCCGAACTCACCACCGAACACCTGCTCTACGCCGCCACCCTGGTCGAACCCACGCGCGGCATC
CTCACCGAAATCGGCCACGACCCCGACGAGCTGAGCATGAAGATGCGCGACGCGGTCTCCGGGCTCAGCGGCAATGGCAA
CGGCAACGGCGGCGCCATCGCCCTCAGCCCCGCGGCCAAACGCGCCATGCGCAACGCCCAGCGCAGCGCCGCCGAAGCCG
GCAGCAGCTACATCGGCCCCGAACACATCCTGCTCGGCATCGCCGAAACCGAGACACCCGCTGCGCAGGCCATGGCGGGC
GCGCAACTGCCGGGCACCGACGGCCAGCGCAAGACCAGCGACACTCCCACCCTCGACGAATACGGCCGCGACCTGACCGC
CGAGGCCCGCGCGGGCAAGGTGGACCCGGTGGTCGGGCGCGCCGAGGAGATCGAGCAGACCGTCGAGATCCTGTCGCGGC
GGCGCAAGAACAACCCGGTGCTCATCGGCGATCCCGGCGTCGGTAAGACCGCCATCGTGGAGGGGCTGGCCCAGCGCATC
GTCAACGGGGATGTGCCGAGCACGCTCGCCGACCGTCGTGTGGTAGCCCTCGATGTCGGTTCCCTGGTCGCGGGCAGCAA
GTACCGGGGCGAATTCGAGGAACGGCTGACCAAGATCCTCGACGAGGTGCGCGCCCACTCCGACGAACTGGTGGTCTTCA
TCGACGAACTACACACCATCGTCGGCGCGGGCAGTGGCTCGGAGGGTTCGATGGACGCGGGCAATCTGCTCAAACCGGCG
CTCGCGCGCGGTGAACTGCACGCCATCGGCGCCACCACCATCGACGAATACCGGCGTCACATCGAAAAGGACGCCGCCCT
GGAACGCCGCTTCCAGCCGGTGATGGTGTCCGAACCGTCGGTCGCCGACACCATCGAGATCCTGCGCGGACTCGCCGACG
TCTACGAAGAACACCACCAGGTGCACTACACCGACGAGTCGCTGATCGCCGCCGCGGAACTGTCCGACCGCTACCTCACC
GACCGATTCATGCCCGACAAGGCCATCGACATGATCGATCAGGCAGGCGCGCGGGTGCGCCTGCGGACCCGCACTCCGGA
CCCCGACATGCGCGAACGCGAGGAAGAGGTGGCCCGGCTGCGCCGGGAGAAGGACGCCGCCGTCGCCGCCGAAGACTACG
AGAAGGCCAAGGAACTCAAATCCGAGATCGCCGTCGCCGAAGAGCAGCTCGCCGGCGCCGGGCAGACCGAGGCGCCGCAG
GTCACCGTCACCGATATCGCGGAGGTCATCTCCCGCCAGACAGGTATCCCGGTATCGGAGTTGACCACCGAAGAACGCCA
GCGGCTGCTCGGGCTCGAGGATGTGCTGCACAAGCGGGTGATCGGCCAGGACGAGGCGATCGTCGCGGTGGCCGAAGCGG
TGCGGCGGGCGCGGGCCGGACTCAAGGATCCGAATCGGCCCATCGGCTCGTTCCTGTTCCTCGGACCCACCGGCGTCGGC
AAGACCGAGCTGGCCAAAGCGCTGGCCGAGGCCGTCTTCGGTGACGAGGACCGGCTCATCCGCTTCGATATGAGCGAATT
CCAGGAAAAGCACACCGTCTCCCGGCTGGTCGGCGCCCCGCCCGGATATGTCGGCTACGACGACGCCGCTCAGCTCACCG
ACAAGGTTCGCCGCCAGCCCTATTCGGTGATCCTGTTCGACGAGATCGAGAAGGCGCATCCGGATGTGTTCAATGTGCTG
CTGCAATTGCTCGACGACGGCCGGGTCACCGATTCCAAGGGCCGCACGGTGGACTTCAAGAACACCATCGTCATCATGAC
CAGCAATATCGGCTCCGATCTGATCCTGTCCGCGCCCGACGGCGATCTGGATTCCATCACACCGACGCTGAACGAGCGCC
TGCGCTCGCATTTCCGCCCCGAATTCCTCAACCGCATCGACGACACCATCGTCTTCCACCGGCTCGACCAGGCGCAGATC
CACCGCATCGTCGACCTGGTGCTCGACGGCACCCGCAGGCTGCTGCACGCCCAGGACATCGACCTCGACGTCACCGATCC
GGCGGTGGACTGGCTCGCCGAACACGGCTACCAACCCGAATTCGGCGCCCGCCCGCTGCGGCGCACGGTGCAGAAAGAGG
TGGACAACAAGCTGTCGCGGCTGCTGCTCGACGGTGATCTGAAATCCGGCGATACCGTGCGGCTGGACGCCGACGGTGGT
GGGTTGCAGTTGGCGGCCGTGGAGCGTCGTGGGGCGAAAACGGTAGAAGCGGCACCGTAA

Protein sequence :
MTESWPSSMSSFDDIFQRFFGPGMSARPPVQRTDLGRLLSDNAKQLVATAQAAAKDWRSPELTTEHLLYAATLVEPTRGI
LTEIGHDPDELSMKMRDAVSGLSGNGNGNGGAIALSPAAKRAMRNAQRSAAEAGSSYIGPEHILLGIAETETPAAQAMAG
AQLPGTDGQRKTSDTPTLDEYGRDLTAEARAGKVDPVVGRAEEIEQTVEILSRRRKNNPVLIGDPGVGKTAIVEGLAQRI
VNGDVPSTLADRRVVALDVGSLVAGSKYRGEFEERLTKILDEVRAHSDELVVFIDELHTIVGAGSGSEGSMDAGNLLKPA
LARGELHAIGATTIDEYRRHIEKDAALERRFQPVMVSEPSVADTIEILRGLADVYEEHHQVHYTDESLIAAAELSDRYLT
DRFMPDKAIDMIDQAGARVRLRTRTPDPDMREREEEVARLRREKDAAVAAEDYEKAKELKSEIAVAEEQLAGAGQTEAPQ
VTVTDIAEVISRQTGIPVSELTTEERQRLLGLEDVLHKRVIGQDEAIVAVAEAVRRARAGLKDPNRPIGSFLFLGPTGVG
KTELAKALAEAVFGDEDRLIRFDMSEFQEKHTVSRLVGAPPGYVGYDDAAQLTDKVRRQPYSVILFDEIEKAHPDVFNVL
LQLLDDGRVTDSKGRTVDFKNTIVIMTSNIGSDLILSAPDGDLDSITPTLNERLRSHFRPEFLNRIDDTIVFHRLDQAQI
HRIVDLVLDGTRRLLHAQDIDLDVTDPAVDWLAEHGYQPEFGARPLRRTVQKEVDNKLSRLLLDGDLKSGDTVRLDADGG
GLQLAAVERRGAKTVEAAP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 5e-170 52

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpC YP_005263661.1 ATP-dependent Clp protease ATP-binding subunit clpC VFG0079 Protein 9e-180 52
clpC YP_005263661.1 ATP-dependent Clp protease ATP-binding subunit clpC VFG0080 Protein 8e-150 50