Gene Information

Name : Sulac_1490 (Sulac_1490)
Accession : YP_005256659.1
Strain : Sulfobacillus acidophilus DSM 10332
Genome accession: NC_016884
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.1.40
Position : 1469987 - 1471702 bp
Length : 1716 bp
Strand : -
Note : PFAM: Pyruvate kinase, barrel domain; PEP-utilising enzyme, mobile domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; COGs: COG0469 Pyruvate kinase; InterPro IPR015793:IPR015794:IPR008279:IPR001697; KEGG: tmr:Tmar_0381 pyruvate kinase;

DNA sequence :
TTGAGACGCACCAAAATTGTGGCCACCATCGGTCCGGCCACGCGCTCATTCGACCGTCTGGCGGCACTGGCCGAAGCCGG
CATGGATGTCGCCCGGATTAATTTATCCCATGGAGACGTTGAAACCCACCGTGAAACCATTCGCCAAATCCGCGCCGTCG
AAACCCAAACGGGCCGACCGCTGGCTATTATGCTGGATACGGCCGGCCCCGAAATCCGGATTACCACCGATGCCGCCGGC
CTGACCCTAGTCCCCGGCCAACGTGTGCGCGTCGGCACCCAGGCAGCCGACATCCAAGTGGACGAGCCACGGATTTTAAC
TCAACTGACGGCCGGGACCCGCCTCATATTAGATGACGGGAATATTGTCCTTCGCATCCTGGCCACCGGCGATCCCTTGG
AAGCCGAAGTGCTCATCGGGGGACGTCTCATGAACCGGAAAAAAATGATTAGCCCGGATCGCCCATGGGATCTAGACATT
CTCACCAAAGAAGATCGGGTGGCCCTGGCTATGGGCGTAGAAGAAGGGGTTGACTGGATTGCCGCGTCTTTTGTGCGAAG
CCCCGACGACATTATCGCCATCCGCCGGGAATTGGAGGACCACGGCCGCCTCATTCCCATTATGGCCAAAATCGAAAACG
TCCAAGCCGTAGAAGCCATTGAGGCCATCGTCACGGTGGCCGACGGGGTCATGGTCGCCCGGGGTGACTTAGGCATTGAA
TTGCCGGTTGAAGAAGTCCCCTGGCTGCAGAAGAAAATTATTGCCGCCGCGAATAGGGCCGGTAAACCGGTGGTCACCGC
CACCCAAATGCTGGAATCGATGATTGCCCACCCGCGTCCCACCCGAGCGGAGGTCACCGATGTGGCTCACGCGATTATGG
ACGGCACCGATGCCGTCATGCTATCGGCCGAAACCGCCAGCGGCGATTATCCGGTGGAAGCCGTGCGGGTGATGGCGCAA
GTGGCAGAAGCCGCCGATCAACAGGCGGAGCATTTTCGCCGTTATCTGACTCGCGGCTCGATTACCGAGGCGGTTTCCCA
TGCGTCCGTAACCGCCGCCGAAGATCTCCAGGCGCGAGCTATTTTAAGTGCCACCGAATCGGGTTCGACCGCCCTGGCGG
TGGCGGCTTTGCGACCGCGCGTACCCATTATCGCCTTGACGCCCTACCTGCCGATTGCTCGCCGGCTTGCGATTGTGTGG
GGCGTAGTGCCGGTGGTAACCGCCCGGGCACACAGTACGGACCAAATGATGGATAACGCGGTGACGACCGCGCTTGCCCA
CGGCTGGGTCGCCTCGGGCGACCGGGTCGTCCTCACCGCCGGCGTCCCCATTGGACAAACCGGGACCACTAATTTAATGC
GGGTCATTACCATTGGTGACATCGTGGTTAAAGGGCAAGGAGTTGGAGTACGGGCCGCCGCCAGCGGGCCGGTCATTACG
GTCCAACGGCCGGACCAGGTAACGCCGCAAGACGTCGTCGGTAAAGTACTGGTGGCGCCCCTGACCAATGAGGAATGGAT
GCCCCTTATCGAGAACGCCAGTGCCATAATTGTTGAATCCGGCGGCTTAACCTCCCACGCCGCCATCGTCGGTCTCTCCC
TCAGAAAGCCCACGATCGTAGGCGCGGTCGATGCCCTGACCAAGGTCCCGGCCGGACAAATCGTGACGGTCGACGGAGCC
CACGGCGTTGTATACCGCGGAACCGTCCAAGTCTAG

Protein sequence :
MRRTKIVATIGPATRSFDRLAALAEAGMDVARINLSHGDVETHRETIRQIRAVETQTGRPLAIMLDTAGPEIRITTDAAG
LTLVPGQRVRVGTQAADIQVDEPRILTQLTAGTRLILDDGNIVLRILATGDPLEAEVLIGGRLMNRKKMISPDRPWDLDI
LTKEDRVALAMGVEEGVDWIAASFVRSPDDIIAIRRELEDHGRLIPIMAKIENVQAVEAIEAIVTVADGVMVARGDLGIE
LPVEEVPWLQKKIIAAANRAGKPVVTATQMLESMIAHPRPTRAEVTDVAHAIMDGTDAVMLSAETASGDYPVEAVRVMAQ
VAEAADQQAEHFRRYLTRGSITEAVSHASVTAAEDLQARAILSATESGSTALAVAALRPRVPIIALTPYLPIARRLAIVW
GVVPVVTARAHSTDQMMDNAVTTALAHGWVASGDRVVLTAGVPIGQTGTTNLMRVITIGDIVVKGQGVGVRAAASGPVIT
VQRPDQVTPQDVVGKVLVAPLTNEEWMPLIENASAIIVESGGLTSHAAIVGLSLRKPTIVGAVDALTKVPAGQIVTVDGA
HGVVYRGTVQV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 2e-62 42
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 2e-62 42
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 2e-62 42
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 4e-62 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Sulac_1490 YP_005256659.1 pyruvate kinase VFG0479 Protein 7e-63 42