Gene Information

Name : STMUK_4475 (STMUK_4475)
Accession : YP_005254914.1
Strain : Salmonella enterica UK-1
Genome accession: NC_016863
Putative virulence/resistance : Virulence
Product : putative DNA helicase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 4692401 - 4695916 bp
Length : 3516 bp
Strand : +
Note : similar to Escherichia coli putative frameshift suppressor (AAC77264.1); superfamily I

DNA sequence :
ATGGATGACAATGCTTTAGGGTTTGCCTCATACTGGCGCAATTCGCTGGCAGATGCTGAGTCAGGAAAGGGCAGTTTTGA
ACGCAAAGACGCCAAAAATTTCACCCACTGGCATGGGATAGCGGCGGGACGTCTTGACGAAACGATCGTTGGTAAATTTT
TTGAGGGAGAAAAAGACGACGTCGAAACAGTCGATGTCATCTTGCGGCCAAAGGTTTATTTCCGGTTACTGCAGCGTGGA
AAGGACCATTCCGCTGGTGCGCCTGATATTGTTACCCCGATAGTGACGCCAGCCCTATTGAGCCGTGAAGGTTTTTTATA
TCCGACGCCAGCGACCTCCATTCCCAGAGACCTGCTTGAACCTTTGCCAAAAGGGGCATTTTCAATTGGTGAGATTGAGC
AGTACGACAAATACAAAACGACACATACGTCATTCTCTATCAACTTTGATGACCGCGTTGATAAGACCGCCGAAACAGAT
GAAGAACGAGAAGCACGATATGCAGCCTGGCAGCAGGATTGGCGTCAATATCTGGATGATTCAGAAAGGCTGCTGAAGAA
CGTTGTCGGCGACTGGATTAAAAATCCTGAGCAATATGAACTCGCTGAGCACGGTTATATTGTTAAAACGGCGCAATCTG
GCGGCGCCAGTTTCCATATCCTTTCACTTTATGATCACCTGCTTGTTTGCAAAAAGGATGTGCCGCTCTTCAATCGTTTC
GCCTCGCGAGAGGTTCATGCTGCAGAGTCATTACTTCCTCCGGAAGCAAAATTCAGCGACAGGATTGGACACTCCGGGGA
TAAGTTTCCGCTGGCAAAGGCTCAGCGCGATGCCTTAAGCCATTTTCTGGATGCGAGGCATGGCGATATCCTTGCCGTTA
ATGGTCCCCCGGGAACCGGAAAAACCACGCTGGTGCTTTCTATCATCGCCACGCAGTGGGCCCGAGCGGCTCTCGAAAAA
GCGGAACCTCCGGTTATTATCGCGACTTCAACGAATAACCAAGCTGTAACGAACATTATCGAGGCGTTCGGGAAAGATTT
TTCCCAAGGCACTGGTGCAATGGCCGGACGATGGTTGCCGGAGCTGAAAAGCTTCGGCGCTTATTTTCCCTCAAGCACTC
GTAAAGCCGAGGCCGCCAAAAAATATCAAACTGAAGATTTCTTCAACCAGGTTGAGTCAAAAGAGTATGTAGAGGATGCA
CTGCTGTTTTATCTGGAGAAAGCTAAGGCAGCCTTTCCTGAAAAAGAGTGTTCATCCCCTGAAAAGGTTATTGAACTCCT
GCATGGTCAGTTGGCAGCAAAATCCGAGCAACTGGTAAGACTGAACGCAACATGGCAAACGTTAAGCCAGGTTCGGGCAA
CGCGAGAGCTTATTGATAACGACATTGAGCAATATCTCGATAATTTAAATAAATTACTCTCCGGGCAAGAACAAAAAGTT
ACTCAACTAAAAAGTGCTAAAGCGGAATGGAAAAAATATCGGGCCAGTGAATCACTGATCTATCCATTATTTTCATGGCT
ACCAGTGGTTCGCAGTAAGCGGCAGTACCAAATACAACTGTTTCTCGAAGATAAATTAGGTGCGCTGATTGCGGGAAATC
AATGGTCGGATCCTGAAACCATCGAACGTAATATCGATAGGTTGCTTAATTCCGCCGAGCGCGAGCAAACAACCTACCGG
CAGCAGATTGACTCCGCGCATGAAATCGTTCTTAAAGAACAGCAGGCGGCTCAGGAATGGCAGAGGCTGGCACTTGATTT
AGGGCATGAGGGCGACGAGGAACTGAGCTTCTCACAGGCAGATGAGCTGGCTGATACGCAGATTCGCTTCCCTGCATTCT
TACTGACGACCCACTACTGGGAAGGTCGTTGGTTGATGGATATGGCCGGCATTGATGATCTGCAGAAAGAAAAGGGCAAG
AAAGGTGCTAAAGGGGTAACAGCTCGCTGGCAACGCCGAATGAAACTTACCCCATGCGTGGTCATGACCTGCTATATGCT
GCCCGGCAATATGCAGATAAGTGAACATAAAGGGCAGCGTAAATTCGAGAAAAGCTATTTATATGACTTCGCCGATTTAC
TCATTGTCGATGAAGCTGGGCAGGTGCTTCCTGAAGTGGCTGCTGCCTCGTTTGCCTTAGCTAAAAAGGCATTAGTGATT
GGTGATACGGAACAGATCCCGCCAATATGGAGTATTACTCCTGCTATTGATATAGGTAACATGCTGGCGGAAAAAATTCT
GTCAGGCAGTACGCAAGAGGAGATTACTGAGAAATATACGGCAATCGCAGAGCTTGGTAAAAGCGCCGCATCTGGCAGCG
TCATGAAAATAGCGCAGTGTGCCTCACGCTATCAATATGATCCCGAACTGGCTCGTGGAATGTACTTATATGAACACCGC
CGGTGCTTCGATAATATTATTGGATACTGCAATACGCTCTGCTATCACGGTAAGTTGTTGCCTAAAAGAGGGTGTGAAGA
GAGCAATTTAATGCCAGCAATGGGTTATCTCCATATTGATGGTAAAGGAGAGCTGGCAAGTAGCGGAAGTCGATATAATT
TGCTGGAGGCTGAAACGATAGCGGCCTGGCTGACAGATAACCAGCAAAGTATTGAAGCGCATTATGGTAAATCGCTTCAT
GAAGTTGTCGGTATCGTGACGCCTTTTAGTGCGCAGGTACCGACCATCAAACAGGCGCTGGATAAACAAGGCATCAGCGC
AGGCACCAATGAAACGTCGCTCACGGTGGGCACAGTCCATTCTCTTCAGGGCGCTGAAAGAGCGATTGTTATATTCTCGC
CAGTCTATTCAAAGCATGAAGACGGCGCGTTTATTGATAGCGATAACAGCATGCTGAATGTTGCTGTCTCCCGAGCTAAG
GACAGTTTCCTGGTCTTCGGCGATATGGACCTGTTTGAGATTCAGCCAGCCTCATCTCCGCGGGGATTACTGGCAAAATA
TCTCTTTGAGTCAGAGAAGAATGCGCTCACTTTTGATTATAAAGAGCGTAAGGATTTAAAAACTGCCGAGACCAAAATCT
ACACACTCCATGGTGTGGAGCAGCATGATAATTTCCTGAATCAGACGTTTGAAAATACCGATAAACACATCACGATAGTT
TCTCCATGGCTAACCTGGCAAAAACTGGAGCAAACCGGTTTTCTTGATTCCATGATTACGGCGTGTTCACGTGGTATTAA
CGTCACGGTAGTCACTGACAGAAGCTACAACACTGAACATAATGATTTTGAGAAGCGAAAAGAGAAGCAGCAGAACCTTA
AAGCGGCGCTGGAGAAACTGAACGCCCTTGGTATTGCGACAAAACTGGTCAATCGTGTTCATAGCAAAATTGTTATTGGT
GATGATGGTTTGCTGTGCGTGGGATCGTTCAACTGGTTTAGCGCGACACGTGAAGCGCGATATGAACGATACGATACATC
GATGGTTTATTGCGGTGATAACCTGAAGGGTGAGATTGAGGCTATTTATAATAGTCTTGATAGGCGTCAGGTTTAG

Protein sequence :
MDDNALGFASYWRNSLADAESGKGSFERKDAKNFTHWHGIAAGRLDETIVGKFFEGEKDDVETVDVILRPKVYFRLLQRG
KDHSAGAPDIVTPIVTPALLSREGFLYPTPATSIPRDLLEPLPKGAFSIGEIEQYDKYKTTHTSFSINFDDRVDKTAETD
EEREARYAAWQQDWRQYLDDSERLLKNVVGDWIKNPEQYELAEHGYIVKTAQSGGASFHILSLYDHLLVCKKDVPLFNRF
ASREVHAAESLLPPEAKFSDRIGHSGDKFPLAKAQRDALSHFLDARHGDILAVNGPPGTGKTTLVLSIIATQWARAALEK
AEPPVIIATSTNNQAVTNIIEAFGKDFSQGTGAMAGRWLPELKSFGAYFPSSTRKAEAAKKYQTEDFFNQVESKEYVEDA
LLFYLEKAKAAFPEKECSSPEKVIELLHGQLAAKSEQLVRLNATWQTLSQVRATRELIDNDIEQYLDNLNKLLSGQEQKV
TQLKSAKAEWKKYRASESLIYPLFSWLPVVRSKRQYQIQLFLEDKLGALIAGNQWSDPETIERNIDRLLNSAEREQTTYR
QQIDSAHEIVLKEQQAAQEWQRLALDLGHEGDEELSFSQADELADTQIRFPAFLLTTHYWEGRWLMDMAGIDDLQKEKGK
KGAKGVTARWQRRMKLTPCVVMTCYMLPGNMQISEHKGQRKFEKSYLYDFADLLIVDEAGQVLPEVAAASFALAKKALVI
GDTEQIPPIWSITPAIDIGNMLAEKILSGSTQEEITEKYTAIAELGKSAASGSVMKIAQCASRYQYDPELARGMYLYEHR
RCFDNIIGYCNTLCYHGKLLPKRGCEESNLMPAMGYLHIDGKGELASSGSRYNLLEAETIAAWLTDNQQSIEAHYGKSLH
EVVGIVTPFSAQVPTIKQALDKQGISAGTNETSLTVGTVHSLQGAERAIVIFSPVYSKHEDGAFIDSDNSMLNVAVSRAK
DSFLVFGDMDLFEIQPASSPRGLLAKYLFESEKNALTFDYKERKDLKTAETKIYTLHGVEQHDNFLNQTFENTDKHITIV
SPWLTWQKLEQTGFLDSMITACSRGINVTVVTDRSYNTEHNDFEKRKEKQQNLKAALEKLNALGIATKLVNRVHSKIVIG
DDGLLCVGSFNWFSATREARYERYDTSMVYCGDNLKGEIEAIYNSLDRRQV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ORF_2 AAZ04413.1 superfamily I DNA helicase Not tested PAI I APEC-O1 Protein 0.0 96
APECO1_3532 YP_854230.1 superfamily I DNA helicase Not tested PAI I APEC-O1 Protein 0.0 96
SF2965 NP_708739.1 superfamily I DNA helicase Not tested SHI-1 Protein 0.0 95
unnamed CAD42018.1 hypothetical protein Not tested PAI II 536 Protein 0.0 95
S3169 NP_838460.1 superfamily I DNA helicase Not tested SHI-1 Protein 0.0 95

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
STMUK_4475 YP_005254914.1 putative DNA helicase VFG0627 Protein 0.0 95
STMUK_4475 YP_005254914.1 putative DNA helicase VFG1537 Protein 0.0 95