Gene Information

Name : safC (STMUK_0307)
Accession : YP_005250867.1
Strain : Salmonella enterica UK-1
Genome accession: NC_016863
Putative virulence/resistance : Virulence
Product : putative fimbrial usher
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 343540 - 346050 bp
Length : 2511 bp
Strand : +
Note : similar to Escherichia coli putative outer membrane protein; export function (AAC73634.1)

DNA sequence :
ATGAAGTTCAAACAACCTGCCTTGCTACTGTTCATCGCGGGAGTGGTTCATTGCGCAAATGCGCACACTTACACATTCGA
TGCATCAATGTTGGGCGATGCAGCGAAAGGGGTTGATATGTCGCTCTTTAACCAGGGGGTACAACAGCCAGGGACTTATC
GCGTGGACGTGATGGTGAATGGTAAACGTGTCGACACCCGTGATGTGGTGTTCAAATTGGAAAAGGATGGGCAAGGAACG
CCTGTTCTGGCTCCTTGTTTGACGGTCAGTCAGCTTTCACGCTACGGCGTAAAAACGGAAGATTACCCTCAGTTGTGGAA
AGCAGCAAAGCCCCCAGATGAGTGTGCGGATCTGACCGCCATTCCACAGGCTAAAGCGGTACTGGATATCAATAATCAGC
AACTGCAACTGAGTATTCCGCAGTTGGCGTTGCGTCCGGAATTTAAGGGGATCGCTCCAGAAGATCTTTGGGATGATGGT
ATTCCGGCGTTTCTGATGAACTACAGTGCGAGGACAACGCAGACGGATTACAAAATGGATATGGTGGGGCGTGACAACTC
TTCCTGGGTACAACTGCAACCGGGAATCAATATAGGTGCGTGGCGTGTCCGCAATGCGACCAGCTGGCAGCGGAGTAGTC
AACTGTCGGGGAAGTGGCAGGCAGCATATACCTATGCTGAGCGTGGACTGTACTCACTAAAAAGTCGTCTGACTCTGGGG
CAAAAGACTTCGCAGGGGGAGATATTTGATAGTGTGCCATTTACCGGTGTGATGTTGGCATCGGATGACAACATGGTGCC
CTACAGTGAGCGGCAGTTTGCTCCGGTAGTGCGTGGGATTGCCCGCACGCAGGCTCGGGTGGAGGTCAAACAGAATGGTT
ACACCATTTACAACACCACTGTGGCGCCCGGACCGTTTGCACTGCGGGATCTGTCGGTAACAGACAGTAGTGGTGATCTG
CATGTCACCGTGTGGGAGGCCGATGGCAGTACACAAATGTTTGTGGTGCCGTATCAGACCCCGGCGATAGCACTGCACCA
GGGATATTTGAAGTACAGCCTGTTGGCGGGCCGATACCGATCGTCAGACTCTGCAACGGATAAGGCGCAGATCGCGCAGG
CTACGTTGATGTATGGTCTGCCGTGGAATCTCACTGCATACGGCGGTATACAGAGTGCAACGCACTATCAAGCTGCATTG
CTTGGTTTGGGGGGATCTCTCGGGCGGTGGGGGAGTTTATCTGTCGATGGAAGCGACACACACAGTCAGCGTCAGGGGGA
GGCGGTACAGCAAGGAGCCTCCTGGCGACTGCGTTACAGCAACCAGCTGACTGCGACGGGGACAAATTTTTTTCTGACGA
GATGGCAGTATGCCTCGCAGGGCTATAACACCCTATCCGATGTGCTCGACAGTTATCGACATAATGGCAACCGTCTATGG
TCGTGGCGGGAAAATTTGCAGCCGAGCTCGCGTACTACCCTGATGTTGAGTCAGTCATGGGGGAGGCATTTGGGCAATCT
GAGTTTAACCGGTTCCCGTACCGACTGGCGTAATCGCCCCGGTCATGATGACAGCTACGGACTGAGTTGGGGAACCTCTA
TCGGAGGGGGCTCGCTGTCATTGAACTGGAATCAAAACAGAACGCTGTGGCGCAATGGCGCGCACCGTAAAGAGAACATA
ACCAGCCTGTGGTTCAGTATGCCATTAAGCCGCTGGACGGGGAATAATGTAAGTGCTAGTTGGCAGATGACTTCACCATC
ACACGGTGGTCAGACGCAACAAGTGGGGGTCAACGGAGAGGCATTCAGTCAGCAACTGGATTGGGAGGTGCGTCAGAGTT
ACCGTGCCGATGCCCCGCCAGGTGGTGGTAATAACAGCGCATTGCACTTGGCATGGAATGGGGATTACGGCCTGTTAGGT
GGTGACTATAGCTACAGCCGGGCGATGCGCCAGATGGGAGTCAATATCGCGGGAGGTATAGTTATCCACCATCATGGTGT
GACGCTGGGGCAACCTTTGCAAGGCTCAGTGGCGCTGGTTGAAGCGCCAGGGGCCTCGGGGGTGCCAGTTGGCGGCTGGC
CTGGCGTTAAGACGGATTTTCGTGGCGACACCACAGTGGGCAACCTGAACGTCTATCAGGAGAATACAGTCAGCCTCGAT
CCGTCGCGACTACCGGATGACGCAGAGGTCACACAAACCGATGTGCGCGTGGTGCCAACCGAAGGGGCGGTGGTGGAAGC
GAAGTTTCACACTCGCATCGGGGCCAGGGCACTGATGACGCTGAAACGGGAAGATGGTAGCGCCATTCCTTTCGGGGCGC
AGGTTACAGTCAATGGGCAGGATGGCAGTGCTGCTCTGGTGGATACTGATAGCCAGGTTTATCTCACTGGTTTGGCGGAT
AAGGGCGAACTGACGGTGAAATGGGGAGCACAGCAATGTCGGGTTAACTACCGCCTACCTGCCCACAAGGGAATCGCGGG
CTTGTATCAAATGAGCGGTCTCTGCAGATAG

Protein sequence :
MKFKQPALLLFIAGVVHCANAHTYTFDASMLGDAAKGVDMSLFNQGVQQPGTYRVDVMVNGKRVDTRDVVFKLEKDGQGT
PVLAPCLTVSQLSRYGVKTEDYPQLWKAAKPPDECADLTAIPQAKAVLDINNQQLQLSIPQLALRPEFKGIAPEDLWDDG
IPAFLMNYSARTTQTDYKMDMVGRDNSSWVQLQPGINIGAWRVRNATSWQRSSQLSGKWQAAYTYAERGLYSLKSRLTLG
QKTSQGEIFDSVPFTGVMLASDDNMVPYSERQFAPVVRGIARTQARVEVKQNGYTIYNTTVAPGPFALRDLSVTDSSGDL
HVTVWEADGSTQMFVVPYQTPAIALHQGYLKYSLLAGRYRSSDSATDKAQIAQATLMYGLPWNLTAYGGIQSATHYQAAL
LGLGGSLGRWGSLSVDGSDTHSQRQGEAVQQGASWRLRYSNQLTATGTNFFLTRWQYASQGYNTLSDVLDSYRHNGNRLW
SWRENLQPSSRTTLMLSQSWGRHLGNLSLTGSRTDWRNRPGHDDSYGLSWGTSIGGGSLSLNWNQNRTLWRNGAHRKENI
TSLWFSMPLSRWTGNNVSASWQMTSPSHGGQTQQVGVNGEAFSQQLDWEVRQSYRADAPPGGGNNSALHLAWNGDYGLLG
GDYSYSRAMRQMGVNIAGGIVIHHHGVTLGQPLQGSVALVEAPGASGVPVGGWPGVKTDFRGDTTVGNLNVYQENTVSLD
PSRLPDDAEVTQTDVRVVPTEGAVVEAKFHTRIGARALMTLKREDGSAIPFGAQVTVNGQDGSAALVDTDSQVYLTGLAD
KGELTVKWGAQQCRVNYRLPAHKGIAGLYQMSGLCR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
safC NP_454907.1 outer-membrane fimbrial usher protein Not tested SPI-6 Protein 0.0 99
afaC AAD44022.2 AfaC Virulence PAI-I AL862 Protein 0.0 50
afaC ADD91743.1 putative AfaC-VIII usher protein Not tested PAI-I AL862 Protein 0.0 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
safC YP_005250867.1 putative fimbrial usher VFG0853 Protein 0.0 50
safC YP_005250867.1 putative fimbrial usher VFG0944 Protein 0.0 50
safC YP_005250867.1 putative fimbrial usher VFG0849 Protein 2e-173 46
safC YP_005250867.1 putative fimbrial usher VFG0857 Protein 2e-169 46
safC YP_005250867.1 putative fimbrial usher VFG0419 Protein 4e-164 44