Gene Information

Name : invG (STMUK_2887)
Accession : YP_005253387.1
Strain : Salmonella enterica UK-1
Genome accession: NC_016863
Putative virulence/resistance : Virulence
Product : outer membrane secretin precursor
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 3010087 - 3011775 bp
Length : 1689 bp
Strand : -
Note : InvG protein precursor (SW:INVG_SALTY); forms ring-shaped structure in outer membrane; requires InvH for stability; type III secretion apparatus

DNA sequence :
ATGAAGACACATATTCTTTTGGCCAGAGTGCTGGCATGTGCCGCGCTTGTTCTGGTTACACCTGGTTATTCTAGTGAAAA
AATACCTGTAACGGGAAGTGGGTTTGTTGCGAAAGACGATAGCCTGCGGACATTTTTCGATGCCATGGCGCTACAGCTAA
AGGAGCCTGTCATTGTTAGCAAAATGGCGGCACGAAAAAAAATTACGGGCAACTTTGAGTTTCACGATCCTAACGCATTA
CTGGAGAAGCTTTCCCTACAACTGGGGCTGATTTGGTATTTCGATGGGCAGGCTATCTATATTTATGACGCCAGTGAAAT
GCGCAATGCCGTGGTTTCTTTACGCAACGTCTCACTCAATGAGTTCAACAATTTTCTAAAACGCTCAGGTTTATATAACA
AAAATTACCCGCTACGTGGCGATAACCGTAAAGGAACATTCTATGTTTCAGGGCCACCCGTCTATGTTGATATGGTGGTC
AACGCCGCCACCATGATGGACAAGCAAAACGATGGTATTGAGCTGGGACGCCAGAAAATAGGGGTGATGCGTCTGAACAA
TACCTTCGTGGGCGATCGTACCTATAATCTGCGCGATCAGAAAATGGTTATTCCCGGTATTGCTACGGCCATTGAAAGGT
TATTGCAGGGAGAAGAGCAACCCTTAGGTAATATTGTCAGTAGCGAACCCCCGGCGATGCCAGCGTTTTCAGCGAATGGA
GAAAAAGGTAAAGCAGCAAATTATGCCGGTGGCATGAGTCTGCAGGAAGCTTTAAAGCAAAATGCCGCGGCGGGCAATAT
TAAAATCGTGGCCTATCCGGATACCAACAGTTTGTTAGTAAAGGGAACGGCTGAGCAGGTGCATTTTATCGAAATGCTGG
TTAAAGCGCTGGATGTCGCCAAACGTCACGTAGAATTATCCCTGTGGATTGTCGATCTTAATAAAAGCGATCTGGAGCGT
TTGGGCACTTCATGGAGCGGCAGCATAACTATTGGGGACAAACTTGGCGTGTCATTAAACCAGTCTTCAATAAGTACCCT
CGATGGCAGTCGATTCATCGCCGCGGTCAATGCGTTAGAAGAGAAGAAACAGGCGACGGTGGTTTCGCGCCCGGTATTAC
TGACTCAGGAAAATGTTCCCGCTATTTTTGATAACAACAGAACGTTTTACACCAAGCTGATTGGGGAACGTAATGTGGCG
CTTGAGCATGTAACATACGGAACAATGATCCGAGTGCTGCCCCGTTTTTCCGCAGATGGTCAGATAGAAATGTCGCTGGA
CATTGAAGATGGCAACGATAAGACGCCGCAATCTGATACTACCACCTCCGTAGATGCGTTACCCGAAGTCGGGCGAACGT
TAATTAGCACTATTGCGAGAGTGCCGCACGGAAAAAGTTTGCTGGTCGGGGGTTATACACGGGATGCAAATACCGATACT
GTCCAAAGTATTCCGTTTTTAGGCAAATTACCGCTTATTGGTAGCCTGTTCCGTTATTCCAGTAAGAATAAAAGTAATGT
TGTTCGTGTGTTCATGATTGAACCAAAAGAAATTGTCGACCCGTTAACGCCGGATGCCAGCGAATCGGTAAACAATATTC
TGAAGCAAAGCGGTGCCTGGAGTGGGGACGATAAGTTACAGAAATGGGTTCGTGTTTATCTGGATAGAGGTCAGGAGGCA
ATTAAATGA

Protein sequence :
MKTHILLARVLACAALVLVTPGYSSEKIPVTGSGFVAKDDSLRTFFDAMALQLKEPVIVSKMAARKKITGNFEFHDPNAL
LEKLSLQLGLIWYFDGQAIYIYDASEMRNAVVSLRNVSLNEFNNFLKRSGLYNKNYPLRGDNRKGTFYVSGPPVYVDMVV
NAATMMDKQNDGIELGRQKIGVMRLNNTFVGDRTYNLRDQKMVIPGIATAIERLLQGEEQPLGNIVSSEPPAMPAFSANG
EKGKAANYAGGMSLQEALKQNAAAGNIKIVAYPDTNSLLVKGTAEQVHFIEMLVKALDVAKRHVELSLWIVDLNKSDLER
LGTSWSGSITIGDKLGVSLNQSSISTLDGSRFIAAVNALEEKKQATVVSRPVLLTQENVPAIFDNNRTFYTKLIGERNVA
LEHVTYGTMIRVLPRFSADGQIEMSLDIEDGNDKTPQSDTTTSVDALPEVGRTLISTIARVPHGKSLLVGGYTRDANTDT
VQSIPFLGKLPLIGSLFRYSSKNKSNVVRVFMIEPKEIVDPLTPDASESVNNILKQSGAWSGDDKLQKWVRVYLDRGQEA
IK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
invG NP_461819.1 outer membrane secretin precursor Virulence SPI-1 Protein 0.0 100
invG NP_457292.1 secretory protein (associated with virulence) Virulence SPI-1 Protein 0.0 99
invG NP_806501.1 virulence-associated secretory protein Virulence SPI-1 Protein 0.0 99
invG YP_217817.1 invasion protein; outer membrane Virulence SPI-1 Protein 0.0 99
ECs3733 NP_311760.1 EivG Not tested LIM Protein 2e-145 55
invG AAS66859.1 InvG Not tested SSR-2 Protein 4e-132 50
ysaC AAS66838.1 YsaC Not tested SSR-1 Protein 9e-93 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
invG YP_005253387.1 outer membrane secretin precursor VFG0559 Protein 0.0 100
invG YP_005253387.1 outer membrane secretin precursor VFG1004 Protein 1e-125 51
invG YP_005253387.1 outer membrane secretin precursor VFG2463 Protein 3e-103 43