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Name : sipA (STMUK_2871) Accession : YP_005253371.1 Strain : Salmonella enterica UK-1 Genome accession: NC_016863 Putative virulence/resistance : Virulence Product : secreted effector protein Function : - COG functional category : - COG ID : - EC number : - Position : 2993169 - 2995226 bp Length : 2058 bp Strand : - Note : Salmonella invasion protein SipA (gi|1172128); binds actin and promotes polymerization; results in membrane ruffling and internalization due to cytoskeleton rearrangements DNA sequence : ATGGTTACAAGTGTAAGGACTCAGCCCCCCGTCATAATGCCAGGTATGCAGACCGAGATCAAAACGCAGGCCACGAATCT TGCGGCGAATCTTTCCGCAGTCAGAGAAAGTGCCACAGCGACGCTGTCAGGGGAAATTAAAGGCCCGCAACTGGAAGATT TTCCCGCGCTGATCAAACAGGCGAGTCTGGATGCATTGTTTAAATGCGGGAAAGACGCTGAGGCGTTAAAAGAAGTTTTT ACCAATTCAAATAATGTCGCCGGTAAGAAAGCGATAATGGAGTTTGCCGGGCTCTTTCGTTCAGCGCTCAACGCCACCAG TGATTCTCCTGAGGCGAAGACGCTACTGATGAAGGTGGGGGCAGAGTATACCGCGCAAATCATAAAAGATGGCCTGAAAG AAAAGTCAGCTTTTGGGCCATGGCTGCCAGAAACAAAGAAAGCGGAAGCGAAGCTGGAAAACCTGGAAAAGCAGCTGTTA GATATTATCAAAAATAACACTGGCGGTGAATTAAGTAAATTATCGACGAATCTTGTTATGCAGGAGGTGATGCCCTATAT TGCCAGCTGCATTGAACATAACTTTGGCTGTACGTTAGATCCGTTAACCCGCAGCAATCTTACGCACCTTGTTGACAAAG CGGCGGCGAAGGCTGTTGAGGCGCTTGATATGTGCCACCAAAAATTAACGCAAGAGCAGGGTACCAGCGTAGGACGGGAA GCCCGGCACCTTGAAATGCAAACGTTGATACCCCTGCTGCTACGTAATGTTTTTGCACAAATTCCTGCAGATAAACTGCC TGACCCTAAAATTCCGGAGCCTGCGGCTGGACCAGTACCTGATGGTGGGAAAAAAGCAGAACCTACGGGTATTAATATCA ATATTAATATTGATAGCAGTAACCATAGCGTGGATAACAGTAAGCATATTAACAATAGCCGAAGCCATGTCGATAATAGC CAGCGCCATATCGATAATAGCAACCATGATAATAGCCGGAAGACGATTGATAATAGCCGAACATTTATTGATAACAGCCA ACGCAATGGCGAGTCACACCATTCGACTAACAGCAGCAACGTAAGTCATAGTCATTCGCGTGTGGATTCGACTACGCATC AAACGGAGACGGCACACAGCGCCAGCACAGGGGCAATTGACCATGGCATCGCGGGTAAAATTGACGTCACGGCTCATGCG ACGGCAGAGGCTGTGACCAACGCTTCATCCGAAAGTAAAGATGGAAAGGTGGTCACGTCAGAAAAGGGCACTACGGGTGA AACAACCTCTTTTGATGAAGTCGATGGCGTAACCAGCAAGAGCATTATCGGCAAGCCGGTACAGGCCACGGTGCACGGCG TTGATGATAATAAACAGCAAAGCCAGACGGCAGAGATTGTGAATGTGAAGCCGCTTGCCAGTCAACTGGCTGGCGTCGAG AATGTTAAAACCGATACCTTACAATCAGACACGACGGTAATTACAGGTAATAAAGCCGGTACGACCGATAATGATAATAG TCAGACAGATAAGACTGGCCCATTTTCTGGTTTGAAGTTTAAGCAAAATAGTTTCCTCTCAACAGTACCGAGCGTTACGA ATATGCATTCAATGCATTTCGACGCCCGTGAGACGTTTTTGGGTGTGATACGTAAAGCCCTGGAGCCAGATACCTCCACA CCGTTCCCTGTACGCAGAGCGTTTGACGGCTTGCGTGCGGAAATATTACCCAATGACACGATAAAGAGTGCAGCGTTGAA AGCGCAATGTAGCGATATTGACAAGCACCCAGAATTGAAAGCGAAAATGGAGACTCTCAAAGAGGTCATTACTCATCATC CACAAAAAGAAAAACTGGCTGAGATTGCACTGCAGTTTGCCAGAGAGGCGGGGCTGACCAGGCTAAAAGGGGAAACTGAC TATGTGTTAAGTAATGTGCTGGACGGCCTTATCGGAGACGGTAGCTGGCGAGCTGGCCCGGCTTACGAGTCATACCTGAA TAAACCTGGCGTGGATCGGGTTATTACTACCGTTGATGGCTTGCACATGCAGCGTTAA Protein sequence : MVTSVRTQPPVIMPGMQTEIKTQATNLAANLSAVRESATATLSGEIKGPQLEDFPALIKQASLDALFKCGKDAEALKEVF TNSNNVAGKKAIMEFAGLFRSALNATSDSPEAKTLLMKVGAEYTAQIIKDGLKEKSAFGPWLPETKKAEAKLENLEKQLL DIIKNNTGGELSKLSTNLVMQEVMPYIASCIEHNFGCTLDPLTRSNLTHLVDKAAAKAVEALDMCHQKLTQEQGTSVGRE ARHLEMQTLIPLLLRNVFAQIPADKLPDPKIPEPAAGPVPDGGKKAEPTGINININIDSSNHSVDNSKHINNSRSHVDNS QRHIDNSNHDNSRKTIDNSRTFIDNSQRNGESHHSTNSSNVSHSHSRVDSTTHQTETAHSASTGAIDHGIAGKIDVTAHA TAEAVTNASSESKDGKVVTSEKGTTGETTSFDEVDGVTSKSIIGKPVQATVHGVDDNKQQSQTAEIVNVKPLASQLAGVE NVKTDTLQSDTTVITGNKAGTTDNDNSQTDKTGPFSGLKFKQNSFLSTVPSVTNMHSMHFDARETFLGVIRKALEPDTST PFPVRRAFDGLRAEILPNDTIKSAALKAQCSDIDKHPELKAKMETLKEVITHHPQKEKLAEIALQFAREAGLTRLKGETD YVLSNVLDGLIGDGSWRAGPAYESYLNKPGVDRVITTVDGLHMQR |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| sipA | NP_461803.1 | secreted effector protein | Virulence | SPI-1 | Protein | 0.0 | 100 |
| sipA | YP_217801.1 | cell invasion protein | Virulence | SPI-1 | Protein | 0.0 | 99 |
| sipA | NP_457276.1 | pathogenicity island 1 effector protein (function unknown) | Virulence | SPI-1 | Protein | 0.0 | 98 |
| sipA | NP_806485.1 | pathogenicity island 1 effector protein | Virulence | SPI-1 | Protein | 0.0 | 98 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| sipA | YP_005253371.1 | secreted effector protein | VFG0543 | Protein | 0.0 | 100 |
