Gene Information

Name : prgK (STMUK_2860)
Accession : YP_005253360.1
Strain : Salmonella enterica UK-1
Genome accession: NC_016863
Putative virulence/resistance : Virulence
Product : needle complex inner membrane lipoprotein
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2983486 - 2984244 bp
Length : 759 bp
Strand : -
Note : PrgK protein precursor (SW:PRGK_SALTY); cell invasion protein; interacts with PrgH and forms oligomeric rings; type III secretion apparatus

DNA sequence :
ATGATTCGTCGATATCTATATACTTTTCTGCTGGTAATGACCCTTGCCGGCTGTAAGGATAAGGATCTTTTAAAAGGACT
GGACCAGGAACAGGCTAATGAGGTCATTGCCGTTCTGCAAATGCACAATATAGAGGCGAATAAAATTGATAGCGGAAAAT
TGGGCTATAGCATTACCGTTGCTGAGCCTGATTTTACCGCTGCGGTGTACTGGATTAAAACTTATCAGCTTCCTCCCCGG
CCACGGGTGGAAATAGCGCAGATGTTCCCGGCGGATTCGCTGGTATCGTCTCCGCGAGCTGAAAAGGCCAGGTTATATTC
GGCTATTGAACAGCGACTGGAACAGTCATTACAGACGATGGAGGGCGTGCTCTCCGCCAGGGTCCATATTAGTTATGATA
TTGATGCTGGTGAAAATGGCCGCCCGCCAAAACCTGTTCATCTGTCGGCATTAGCCGTATATGAACGAGGTTCGCCGCTT
GCGCATCAGATCAGCGATATCAAGCGTTTCTTAAAGAATAGTTTTGCCGATGTGGATTATGACAACATTTCTGTTGTGTT
GTCAGAACGTTCTGATGCCCAATTACAGGCTCCCGGCACACCAGTAAAACGTAATTCTTTTGCAACCAGTTGGATTGTTT
TGATTATTTTGTTATCCGTGATGTCAGCAGGCTTTGGCGTCTGGTATTACAAAAACCATTATGCCCGCAATAAGAAAGGC
ATAACGGCTGATGATAAGGCGAAATCGTCAAATGAATAG

Protein sequence :
MIRRYLYTFLLVMTLAGCKDKDLLKGLDQEQANEVIAVLQMHNIEANKIDSGKLGYSITVAEPDFTAAVYWIKTYQLPPR
PRVEIAQMFPADSLVSSPRAEKARLYSAIEQRLEQSLQTMEGVLSARVHISYDIDAGENGRPPKPVHLSALAVYERGSPL
AHQISDIKRFLKNSFADVDYDNISVVLSERSDAQLQAPGTPVKRNSFATSWIVLIILLSVMSAGFGVWYYKNHYARNKKG
ITADDKAKSSNE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
prgK YP_217790.1 cell invasion protein Virulence SPI-1 Protein 3e-116 100
prgK NP_461792.1 needle complex inner membrane lipoprotein Virulence SPI-1 Protein 3e-116 100
prgK NP_457265.1 pathogenicity 1 island effector protein Virulence SPI-1 Protein 3e-115 99
prgK NP_806474.1 pathogenicity island 1 effector protein Virulence SPI-1 Protein 3e-115 99
prgK AAS66872.1 PrgK Virulence SSR-2 Protein 5e-57 58
ECs3716 NP_311743.1 EprK Not tested LIM Protein 3e-54 56
eprK AAZ31284.1 EprK Virulence ETT2 Protein 3e-53 55

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
prgK YP_005253360.1 needle complex inner membrane lipoprotein VFG0533 Protein 1e-116 100
prgK YP_005253360.1 needle complex inner membrane lipoprotein VFG0998 Protein 3e-45 47
prgK YP_005253360.1 needle complex inner membrane lipoprotein VFG1787 Protein 2e-37 46