Gene Information

Name : clpB (STMUK_2696)
Accession : YP_005253202.1
Strain : Salmonella enterica UK-1
Genome accession: NC_016863
Putative virulence/resistance : Unknown
Product : protein disaggregation chaperone
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2804286 - 2806859 bp
Length : 2574 bp
Strand : -
Note : similar to Escherichia coli heat shock protein (AAC75641.1); Hsp 100; part of novel multi-chaperone system with DnaK, DnaJ, and GrpE

DNA sequence :
ATGCGTCTGGATCGTCTTACTAACAAATTCCAGCTTGCTCTTGCCGATGCCCAGTCGCTCGCGCTGGGGCACGACAACCA
ATTCATCGAACCTCTTCATTTAATGAGCGCCTTGCTGAACCAGGAAGGGGGATCGATACGTCCTTTATTAACCTCCGCCG
GCATTAATGCTGGCCAGTTGCGCACCGCTATCGATCAGGCGCTGAGCCGTTTACCGCAGGTGGAAGGCACCGGCGGCGAC
GTACAGCCTTCTTCGGAACTGGTACGCGTACTGAACCTTTGCGACAAGCTGGCGCAAAAACGGGGAGACAATTTTATTTC
GTCAGAGCTGTTTGTTCTGGCGGCGCTTGAGTCTCGCGGCACGTTAACCGATCTGCTGAAATCAGCCGGTGCGACCACGG
CCAATATCACTCAGGCAATTGAACAGATGCGCGGAGGTGAAAGCGTGAACGATCAAGGGGCTGAAGACCAACGTCAGGCC
TTGAAAAAATATACCGTCGATCTGACCGAGCGGGCTGAACAAGGCAAGCTTGACCCGGTAATTGGTCGTGATGAAGAAAT
TCGCCGTACCATTCAGGTACTGCAACGTCGTACCAAAAACAACCCGGTGTTAATCGGTGAGCCAGGGGTCGGTAAAACGG
CAATTGTTGAAGGACTGGCGCAGCGCATTATTAACGGTGAAGTCCCTGAAGGCTTAAAAGGTCGCCGCGTACTGGCGCTG
GATATGGGCGCGCTGGTGGCGGGGGCGAAATATCGCGGCGAATTTGAAGAGCGTCTGAAAGGCGTGCTGAACGATCTGGC
GAAACAGGAAGGCAACGTCATCCTGTTTATTGACGAGCTGCACACGATGGTTGGCGCAGGTAAGGCTGATGGCGCAATGG
ACGCCGGGAATATGCTGAAACCGGCGCTGGCGCGTGGTGAACTGCACTGTGTGGGCGCCACCACGCTGGATGAATACCGT
CAGTACATTGAAAAAGACGCGGCGCTGGAACGTCGTTTTCAAAAAGTGTTTGTCGCAGAACCTTCAGTGGAAGACACCAT
CGCTATTCTGCGTGGCCTGAAAGAACGTTACGAGCTGCACCACCATGTGCAGATCACTGACCCGGCGATTGTGGCGGCGG
CAACATTATCTCACCGCTATATCGCCGACCGTCAGTTGCCGGATAAAGCTATCGACCTCATCGATGAAGCTGCATCCAGC
ATTCGTATGCAGATTGACTCTAAGCCGGAGGAGCTGGACAGACTCGACCGCCGCATTATTCAGCTCAAACTGGAACAGCA
GGCGTTGATGAAAGAGTCTGACGAGGCGAGTAAAAAACGTCTCGATATGCTCAACGAAGAACTGGACGACAAAGAGCGCC
AGTATTCTGAGCTGGAAGAAGAGTGGAAAGCGGAAAAAGCGTCGCTCTCTGGTACGCAAACTATTAAAGCGGAGCTGGAG
CAGGCGAAGATTGCCATCGAGCAGGCGCGTCGCGTTGGCGACCTGGCGCGAATGTCTGAACTGCAGTACGGCAAAATTCC
GGAGCTGGAAAAACAGCTGGAAGCCGCGACCCAGTCGGAAGGTAAAACCATGCGTCTGTTACGTAACAAAGTAACGGATG
CGGAAATTGCCGAAGTGCTAGCGCGCTGGACCGGTATTCCGGTTTCCAGAATGCTGGAAGGCGAACGTGAAAAACTGTTG
CGTATGGAACAAGAGTTACACAGCCGTGTGATCGGGCAGAATGAAGCCGTTGAAGCAGTATCGAACGCCATACGTCGTAG
CCGTGCTGGGCTGTCCGATCCGAACCGTCCGATTGGTTCCTTCCTGTTCCTGGGGCCGACGGGGGTCGGTAAAACCGAAC
TGTGTAAAGCACTGGCTAACTTTATGTTCGACAGCGACGACGCGATGGTGCGTATCGACATGTCTGAGTTTATGGAGAAA
CACTCCGTGTCTCGTTTGGTCGGGGCGCCTCCGGGATATGTCGGCTATGAAGAAGGCGGTTATTTGACGGAAGCGGTGCG
CCGTCGCCCTTATTCCGTCATCTTGTTGGATGAAGTGGAAAAAGCGCATCCGGATGTATTCAACATTCTGTTGCAGGTGC
TGGACGACGGTCGACTGACTGACGGGCAGGGGAGAACGGTCGACTTCCGTAATACGGTGGTCATTATGACTTCTAACCTC
GGTTCCGATCTCATTCAGGAGCGCTTTGGCGAACTGGATTACGGTCGAATGAAAGAGATGGTGCTGGGTGTGGTTAGCCA
AAACTTCCGTCCGGAATTTATCAACCGTATTGATGAAGTTGTGGTATTCCATCCGTTAGGTGAACAACACATCGCTTCTA
TTGCTCAGATCCAGCTGCAGCGTCTGTACAAACGTCTGGAAGAACGTGGTTATGAAATCCATATCTCCGACGAGGCGCTG
AAACTGTTGAGCGCCAACGGTTACGATCCGGTCTACGGGGCGCGTCCGTTAAAACGTGCTATTCAACAGCAGATCGAAAA
CCCACTGGCGCAGCAAATCCTGTCTGGTGAACTGGTTCCTGGCAAAGTGATTCGCCTTGAAGCCAATGATGATCGTATTG
TGGCAGTGCAGTAA

Protein sequence :
MRLDRLTNKFQLALADAQSLALGHDNQFIEPLHLMSALLNQEGGSIRPLLTSAGINAGQLRTAIDQALSRLPQVEGTGGD
VQPSSELVRVLNLCDKLAQKRGDNFISSELFVLAALESRGTLTDLLKSAGATTANITQAIEQMRGGESVNDQGAEDQRQA
LKKYTVDLTERAEQGKLDPVIGRDEEIRRTIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIINGEVPEGLKGRRVLAL
DMGALVAGAKYRGEFEERLKGVLNDLAKQEGNVILFIDELHTMVGAGKADGAMDAGNMLKPALARGELHCVGATTLDEYR
QYIEKDAALERRFQKVFVAEPSVEDTIAILRGLKERYELHHHVQITDPAIVAAATLSHRYIADRQLPDKAIDLIDEAASS
IRMQIDSKPEELDRLDRRIIQLKLEQQALMKESDEASKKRLDMLNEELDDKERQYSELEEEWKAEKASLSGTQTIKAELE
QAKIAIEQARRVGDLARMSELQYGKIPELEKQLEAATQSEGKTMRLLRNKVTDAEIAEVLARWTGIPVSRMLEGEREKLL
RMEQELHSRVIGQNEAVEAVSNAIRRSRAGLSDPNRPIGSFLFLGPTGVGKTELCKALANFMFDSDDAMVRIDMSEFMEK
HSVSRLVGAPPGYVGYEEGGYLTEAVRRRPYSVILLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFRNTVVIMTSNL
GSDLIQERFGELDYGRMKEMVLGVVSQNFRPEFINRIDEVVVFHPLGEQHIASIAQIQLQRLYKRLEERGYEIHISDEAL
KLLSANGYDPVYGARPLKRAIQQQIENPLAQQILSGELVPGKVIRLEANDDRIVAVQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 2e-101 43
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 1e-99 41
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 9e-100 41