Gene Information

Name : copR (STMUK_1065)
Accession : YP_005251606.1
Strain : Salmonella enterica UK-1
Genome accession: NC_016863
Putative virulence/resistance : Virulence
Product : transcriptional regulatory protein YedW
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1141272 - 1142018 bp
Length : 747 bp
Strand : -
Note : induced by CusR in the presence of copper; YedW induces the expression of the upstream gene yedV (encoding a sensor kinase) as well as yedW; yedVW is one of four copper regulons found in E. coli; part of the copper homeostasis mechanism; confers resistanc

DNA sequence : 
ATGACAATTATGTCATCTTGTTGGAGATTTACGGATTCGCTAACAAGCCTATGGCATACTGCGTTGATGAAGATTTTATT
GATTGAAGATAACCAGAAAACCATTGAGTGGGTACGTCAGGGACTCACGGAAGCAGGCTATGTGGTTGATTATGCCTGTG
ATGGACGAGACGGATTACACCTGGCCCTTCAGGAACATTATTCATTGATTATTCTTGATATTATGCTGCCGGGGCTTGAT
GGATGGCAGGTTTTACGCGCGTTACGCACTGCGCATCAGTCCCCTGTTATTTGCCTGACGGCGCGCGACTCGGTTGAGGA
TCGCGTCAAAGGTCTTGAGGCGGGCGCTAATGATTACCTTGTTAAGCCTTTTTCCTTCGCCGAACTGCTGGCCCGGGTGA
GAGCTCAACTCAGACAGCATGTCCCTGCCTTTACTCGACTGACGATCAATGGTCTGGACATGGATGCCACAAAGCAATCA
GTGTCACGAAATGGCAAACCGATTTCCCTGACCCGCAAAGAATTCCTGCTCCTCTGGTTACTGGCGTCCCGGGCAGGAGA
AATCGTGCCCCGAACCGCGATCGCCAGCGAAGTTTGGGGAATTAACTTTGATAGTGAAACCAACACCGTTGATGTCGCGA
TTCGTCGGCTGCGCGCCAAAGTAGACGATCCATTTGAAAAGAAGCTCATTATGACCGTCCGGGGGATGGGTTATCGATTA
CAGGCGGAAACGTCGCAGAATGGTTAA

Protein sequence : 
MTIMSSCWRFTDSLTSLWHTALMKILLIEDNQKTIEWVRQGLTEAGYVVDYACDGRDGLHLALQEHYSLIILDIMLPGLD
GWQVLRALRTAHQSPVICLTARDSVEDRVKGLEAGANDYLVKPFSFAELLARVRAQLRQHVPAFTRLTINGLDMDATKQS
VSRNGKPISLTRKEFLLLWLLASRAGEIVPRTAIASEVWGINFDSETNTVDVAIRRLRAKVDDPFEKKLIMTVRGMGYRL
QAETSQNG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
copR NP_460069.2 transcriptional regulatory protein YedW Not tested SPI-5 Protein 3e-103 100
copR AAC33719.1 regulatory protein CopR Not tested SPI-5 Protein 1e-112 98

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
copR YP_005251606.1 transcriptional regulatory protein YedW BAC0197 Protein 2e-59 59
copR YP_005251606.1 transcriptional regulatory protein YedW BAC0083 Protein 9e-56 57
copR YP_005251606.1 transcriptional regulatory protein YedW BAC0125 Protein 4e-60 56
copR YP_005251606.1 transcriptional regulatory protein YedW BAC0638 Protein 7e-53 56
copR YP_005251606.1 transcriptional regulatory protein YedW BAC0308 Protein 8e-55 55
copR YP_005251606.1 transcriptional regulatory protein YedW BAC0111 Protein 8e-57 53
copR YP_005251606.1 transcriptional regulatory protein YedW BAC0347 Protein 3e-50 52
copR YP_005251606.1 transcriptional regulatory protein YedW NC_007793.3914065.p0 Protein 3e-40 45
copR YP_005251606.1 transcriptional regulatory protein YedW NC_002758.1121390.p0 Protein 3e-40 45
copR YP_005251606.1 transcriptional regulatory protein YedW NC_010079.5776364.p0 Protein 3e-40 45
copR YP_005251606.1 transcriptional regulatory protein YedW NC_002952.2859858.p0 Protein 3e-40 45
copR YP_005251606.1 transcriptional regulatory protein YedW NC_007622.3794948.p0 Protein 3e-40 45
copR YP_005251606.1 transcriptional regulatory protein YedW AE015929.1.gene1106. Protein 2e-34 45
copR YP_005251606.1 transcriptional regulatory protein YedW NC_003923.1003417.p0 Protein 3e-40 45
copR YP_005251606.1 transcriptional regulatory protein YedW NC_013450.8614146.p0 Protein 3e-40 45
copR YP_005251606.1 transcriptional regulatory protein YedW NC_002951.3238224.p0 Protein 3e-40 45

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
copR YP_005251606.1 transcriptional regulatory protein YedW VFG0596 Protein 1e-103 100
copR YP_005251606.1 transcriptional regulatory protein YedW VFG0473 Protein 7e-30 42
copR YP_005251606.1 transcriptional regulatory protein YedW VFG1389 Protein 3e-32 42
copR YP_005251606.1 transcriptional regulatory protein YedW VFG1390 Protein 4e-38 41