Gene Information

Name : STMDT12_C29430 (STMDT12_C29430)
Accession : YP_005248639.1
Strain : Salmonella enterica T000240
Genome accession: NC_016860
Putative virulence/resistance : Virulence
Product : flagellum-specific ATP synthase SpaL
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 3060107 - 3061402 bp
Length : 1296 bp
Strand : -
Note : COG1157 Flagellar biosynthesis/type III secretory pathway ATPase

DNA sequence :
ATGAAAACACCTCGTTTACTGCAATATCTGGCCTACCCACAAAAAATAACCGGCCCAATTATTGAGGCGGAATTGCGCGA
TGTGGCCATTGGCGAACTGTGTGAAATACGCCGTGGCTGGCACCAAAAACAGGTTGTTGCACGTGCGCAGGTGGTTGGCT
TACAGCGGGAACGCACCGTGCTGAGCCTTATCGGCAATGCCCTGGGGCTGAGCCGCGATGTCGTGCTTTATCCCACTGGA
CGTGCGTTATCGGCGTGGGTGGGATACTCGGTATTAGGCGCGGTGTTGGATCCGACAGGGAAAATCGTTGAGCGTTTTAC
CCCTGAAGTGGCGCCGATTAGCGAAGAACGCGTTATTGATGTCGCACCGCCGTCTTACGCTTCACGCGTTGGCGTCCGTG
AACCGCTGATTACCGGTGTGCGCGCGATTGACGGGTTATTGACCTGTGGCGTAGGCCAGCGAATGGGCATTTTTGCCTCC
GCAGGATGCGGTAAGACCATGCTGATGCATATGCTGATCGAGCAAACGGAGGCGGATGTCTTTGTTATCGGTCTTATCGG
TGAACGAGGCCGTGAGGTCACTGAATTCGTGGATATGTTGCGCGCTTCGCATAAGAAAGAAAAATGCGTGCTGGTTTTTG
CCACTTCCGATTTCCCCTCGGTCGATCGCTGCAATGCGGCGCAACTGGCGACAACCGTAGCGGAATATTTTCGCGACCAG
GGAAAACGGGTCGTGCTTTTTATCGATTCCATGACCCGTTATGCGCGTGCTTTGCGAGACGTGGCACTGGCGTCGGGAGA
GCGTCCGGCTCGTCGAGGTTATCCCGCCTCCGTATTCGATAATTTGCCCCGCTTGCTGGAACGCCCAGGGGCGACCAGCG
AGGGAAGCATTACTGCCTTTTATACGGTACTGCTGGAAAGCGAGGAAGAGGCGGACCCGATGGCGGATGAAATTCGCTCT
ATCCTTGACGGTCACCTGTATCTGAGCAGAAAGCTGGCCGGGCAGGGACATTACCCGGCAATCGATGTACTGAAAAGCGT
AAGCCGCGTTTTTGGACAAGTCACGACGCCGACACATGCTGAACAGGCATCTGCCGTGCGTAAATTAATGACGCGTTTGG
AAGAGCTCCAGCTTTTCATTGACTTGGGAGAATATCGTCCTGGCGAAAATATCGATAACGATCGGGCGATGCAGATGCGG
GATAGCCTGAAAGCCTGGTTATGCCAGCCGGTAGCGCAGTATTCATCCTTTGATGACACGTTGAGCGGTATGAATGCATT
CGCTGACCAGAATTAA

Protein sequence :
MKTPRLLQYLAYPQKITGPIIEAELRDVAIGELCEIRRGWHQKQVVARAQVVGLQRERTVLSLIGNALGLSRDVVLYPTG
RALSAWVGYSVLGAVLDPTGKIVERFTPEVAPISEERVIDVAPPSYASRVGVREPLITGVRAIDGLLTCGVGQRMGIFAS
AGCGKTMLMHMLIEQTEADVFVIGLIGERGREVTEFVDMLRASHKKEKCVLVFATSDFPSVDRCNAAQLATTVAEYFRDQ
GKRVVLFIDSMTRYARALRDVALASGERPARRGYPASVFDNLPRLLERPGATSEGSITAFYTVLLESEEEADPMADEIRS
ILDGHLYLSRKLAGQGHYPAIDVLKSVSRVFGQVTTPTHAEQASAVRKLMTRLEELQLFIDLGEYRPGENIDNDRAMQMR
DSLKAWLCQPVAQYSSFDDTLSGMNAFADQN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 0.0 99
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 0.0 99
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 0.0 99
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 0.0 99
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 9e-133 64
invC AAS66861.1 InvC Not tested SSR-2 Protein 2e-132 63
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 9e-111 56
escN AAC31513.1 L0034 Virulence LEE Protein 2e-71 49
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 2e-71 49
escN YP_003236088.1 translocator EscN Virulence LEE Protein 2e-71 49
escN AAC38383.1 EscN Virulence LEE Protein 7e-72 49
escN NP_290268.1 hypothetical protein Virulence LEE Protein 3e-71 49
ECs4568 NP_312595.1 EscN Virulence LEE Protein 3e-71 49
escN CAI43874.1 EscN protein Virulence LEE Protein 1e-70 48
escN AAK26715.1 EscN Virulence LEE Protein 3e-70 48
escN AAL57542.1 EscN Virulence LEE Protein 3e-70 48
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 2e-70 48
escN YP_003223475.1 translocator EscN Virulence LEE Protein 1e-70 48
escN CAC81862.1 EscN protein Virulence LEE II Protein 1e-70 48
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 3e-70 47
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 3e-70 47
lscN AAO18044.1 LscN Virulence TTSS locus Protein 5e-85 46
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 4e-83 46
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 4e-82 45
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 6e-82 45
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 2e-67 45
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 2e-71 45
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 2e-71 45
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 2e-71 45
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 1e-71 45
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 3e-71 45
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 9e-74 45
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 4e-83 44
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-82 44
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 5e-83 44
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 4e-83 44
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-81 44
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-81 44
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 8e-69 44
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 2e-70 44
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 1e-68 44
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 1e-68 44
unnamed AAL06369.1 EscN Virulence LEE Protein 7e-70 43
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 7e-59 42
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 3e-60 41
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 5e-62 41
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 4e-62 41
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 2e-60 41
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 9e-59 41
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 9e-59 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
STMDT12_C29430 YP_005248639.1 flagellum-specific ATP synthase SpaL VFG0555 Protein 0.0 99
STMDT12_C29430 YP_005248639.1 flagellum-specific ATP synthase SpaL VFG2459 Protein 8e-118 59
STMDT12_C29430 YP_005248639.1 flagellum-specific ATP synthase SpaL VFG1008 Protein 3e-119 59
STMDT12_C29430 YP_005248639.1 flagellum-specific ATP synthase SpaL VFG1778 Protein 1e-107 58
STMDT12_C29430 YP_005248639.1 flagellum-specific ATP synthase SpaL VFG0730 Protein 4e-72 49
STMDT12_C29430 YP_005248639.1 flagellum-specific ATP synthase SpaL VFG0812 Protein 1e-71 49
STMDT12_C29430 YP_005248639.1 flagellum-specific ATP synthase SpaL VFG0192 Protein 4e-83 47
STMDT12_C29430 YP_005248639.1 flagellum-specific ATP synthase SpaL VFG0390 Protein 2e-87 46
STMDT12_C29430 YP_005248639.1 flagellum-specific ATP synthase SpaL VFG0048 Protein 3e-82 45
STMDT12_C29430 YP_005248639.1 flagellum-specific ATP synthase SpaL VFG0515 Protein 9e-72 45
STMDT12_C29430 YP_005248639.1 flagellum-specific ATP synthase SpaL VFG2144 Protein 5e-68 43
STMDT12_C29430 YP_005248639.1 flagellum-specific ATP synthase SpaL VFG1254 Protein 3e-62 41