Gene Information

Name : metB (STM14_4928)
Accession : YP_005240381.1
Strain : Salmonella enterica 14028S
Genome accession: NC_016856
Putative virulence/resistance : Unknown
Product : cystathionine gamma-synthase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 4323157 - 4324458 bp
Length : 1302 bp
Strand : +
Note : catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine

DNA sequence :
ATGCATATAATTTTAACGGCTATTTGCGGTTTGCTCAATCTATACGCAAAGAAGTTTAGATGTCCAGATGTATTGACGTC
TATTGTGGTAGTGGTTAATCTGTGGCCTGACTTTCACCGACTCAGCCAGGAATATCTTCATATGACGCGTAAACAGGCCA
CTATCGCAGTGCGTAGCGGATTAAACGATGACGAACAATACGGCTGCGTTGTGCCGCCAATCCATCTCTCCAGTACCTAT
AACTTTACCGGTTTCAATGAGCCGCGCGCGCATGATTATTCCCGCCGCGGTAATCCCACGCGTGATGTTGTTCAGCGCGC
ATTAGCGGAACTGGAAGGCGGCGCGGGCGCGGTATTGACGAATACCGGCATGTCGGCGATTCATCTGGTCACCACCGTTT
TCCTCAAGCCGGGCGATCTGCTGGTCGCGCCGCATGATTGCTATGGCGGCAGTTATCGTCTGTTTGACAGTCTGGCGACA
CGCGGCTGTTATCGTGTGCGGTTTGTCGATCAGGGCGATGAACGCGCCTTACAGGCGGCGCTGGAAGAAAAACCGAAGCT
GGTACTGGTAGAAAGTCCAAGTAATCCATTGTTACGCGTGGTGGATATTGCGAAAATCTGTCGGCTGGCGCGCGAGGCGG
GCGCAGTGAGCGTCGTTGATAACACGTTTTTAAGCCCGGCGCTGCAAAATCCGCTGGCGTTGGGTGCCGATCTGGTGTTG
CATTCATGCACGAAATATCTCAACGGTCATTCGGATGTCGTGGCCGGCGTGGTGATTGCTAAAGATCCGGAAGTGGTCAC
TGAACTGGCGTGGTGGGCGAATAATATTGGCGTGACCGGCGGGGCGTTTGATAGCTATCTGCTGCTGCGCGGTTTGCGAA
CTCTGGTGCCGCGTATGGAGCTGGCGCAGCGCAACGCGCAGGCGATTGTGAAATATCTGCAAACCCAGCCGTTGGTGAAA
AAACTGTATCATCCGTCGCTGCCGGAAAATCAGGGGCATGAAATTGCCGCGCGCCAGCAAAAAGGCTTTGGCGCAATGTT
GAGTTTTGAACTGGATGGGGATGAGGAGACGCTGCGTCGTTTTCTGGGCGGGCTGTCGCTGTTTACGCTGGCGGAATCTT
TAGGGGGAGTGGAAAGTTTGATCTCTCACGCCGCCACCATGACGCATGCCGGTATGTCGCCGCAGGCGCGTGCCTCCGCC
GGGATCTCCGAAACGCTACTGCGTATCTCCACCGGTATTGAAGATGGCGAAGATTTAATTGCCGACCTGGAAAATGGCTT
CCGGGCTGCAAACAAGGGGTAA

Protein sequence :
MHIILTAICGLLNLYAKKFRCPDVLTSIVVVVNLWPDFHRLSQEYLHMTRKQATIAVRSGLNDDEQYGCVVPPIHLSSTY
NFTGFNEPRAHDYSRRGNPTRDVVQRALAELEGGAGAVLTNTGMSAIHLVTTVFLKPGDLLVAPHDCYGGSYRLFDSLAT
RGCYRVRFVDQGDERALQAALEEKPKLVLVESPSNPLLRVVDIAKICRLAREAGAVSVVDNTFLSPALQNPLALGADLVL
HSCTKYLNGHSDVVAGVVIAKDPEVVTELAWWANNIGVTGGAFDSYLLLRGLRTLVPRMELAQRNAQAIVKYLQTQPLVK
KLYHPSLPENQGHEIAARQQKGFGAMLSFELDGDEETLRRFLGGLSLFTLAESLGGVESLISHAATMTHAGMSPQARASA
GISETLLRISTGIEDGEDLIADLENGFRAANKG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 4e-61 43
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-62 43
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 1e-50 41