Gene Information

Name : sicA (STM14_3485)
Accession : YP_005238995.1
Strain : Salmonella enterica 14028S
Genome accession: NC_016856
Putative virulence/resistance : Virulence
Product : secretion chaperone
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 3051135 - 3051632 bp
Length : 498 bp
Strand : -
Note : surface presentation of antigens protein SpaT (SW:SPAT_SALTY); surface presentation of antigens; secretory proteins; partitioning factor for SipB/C; prevents premature association of SipB/C; regulates several promoters with InvF

DNA sequence : 
ATGGATTATCAAAATAATGTCAGCGAAGAACGTGTTGCGGAAATGATTTGGGATGCCGTTAGTGAAGGCGCCACGCTAAA
AGACGTTCATGGGATCCCTCAAGATATGATGGACGGTTTATATGCTCATGCTTATGAGTTTTATAACCAGGGACGACTGG
ATGAAGCTGAGACGTTCTTTCGTTTCTTATGCATTTATGATTTTTACAATCCCGATTACACCATGGGACTGGCGGCAGTA
TGCCAACTGAAAAAACAATTTCAGAAAGCATGTGACCTTTATGCAGTAGCGTTTACGTTACTTAAAAATGATTATCGCCC
CGTTTTTTTTACCGGGCAGTGTCAATTATTAATGCGTAAGGCAGCAAAAGCCAGACAGTGTTTTGAACTTGTCAATGAAC
GTACTGAAGATGAGTCTCTGCGGGCAAAAGCGTTGGTCTATCTGGAGGCGCTAAAAACGGCGGAGACAGAGCAGCACAGT
GAACAAGAAAAGGAATAA

Protein sequence : 
MDYQNNVSEERVAEMIWDAVSEGATLKDVHGIPQDMMDGLYAHAYEFYNQGRLDEAETFFRFLCIYDFYNPDYTMGLAAV
CQLKKQFQKACDLYAVAFTLLKNDYRPVFFTGQCQLLMRKAAKARQCFELVNERTEDESLRAKALVYLEALKTAETEQHS
EQEKE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
sicA YP_217805.1 surface presentation of antigens; secretory proteins Virulence SPI-1 Protein 6e-73 100
spaT NP_457280.1 unknown function Virulence SPI-1 Protein 6e-73 100
spaT NP_806489.1 hypothetical protein Virulence SPI-1 Protein 6e-73 100
sicA NP_461807.1 secretion chaperone Virulence SPI-1 Protein 6e-73 100
sycB AAS66850.1 SycB Not tested SSR-1 Protein 4e-34 55
sicA AAS66869.1 SicA Virulence SSR-2 Protein 6e-28 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
sicA YP_005238995.1 secretion chaperone VFG0547 Protein 2e-73 100
sicA YP_005238995.1 secretion chaperone VFG0988 Protein 4e-44 60
sicA YP_005238995.1 secretion chaperone VFG2451 Protein 7e-46 60
sicA YP_005238995.1 secretion chaperone VFG1769 Protein 3e-40 52