Gene Information

Name : troB (TPECDC2_0164)
Accession : YP_005229955.1
Strain : Treponema pallidum CDC2
Genome accession: NC_016848
Putative virulence/resistance : Virulence
Product : iron (Fe2+)/zinc (Zn2+)/manganese (Mn2+) ABC superfamily ATP binding cassette transporter, ABC protein
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 186781 - 187581 bp
Length : 801 bp
Strand : +
Note : -

DNA sequence : 
ATGGCAGAGATATCAGCAACAGCTTATGCTGTCCAGGTTGACGACCTGACGCTTGCGTATCGGCAGAAGCCGGTGCTTTG
GGACGTGGATGTGCGTATTCCAGAGGGGGTTATCGAGGCCATTATCGGTCCTAATGGGGCGGGCAAGTCGACCCTATTGA
AGGCGATCATGGGTCTTCTGCCTCTCGCTTCCGGAGAGGTGCGTGTCTTTGGGCGTCCTTTTTCAAAGGAGCGGCGGCGT
GTTGCGTATGTCCCGCAGCGCAGTGCAGTGGATTGGGATTTCCCTACTACCGTTTTTGATGTGGTGCTCATGGGTTCGTA
CGGTTTGCTCGGTTGGATTCGTCGTCCGGGAAAAAGAGAAAAGGCGCGTGCCCGGGAAGCGATCGAGGAAGTAGGAATGG
GCGCCTTTTTAGACCGACAAATCAGTGAGCTTTCAGGCGGTCAGCAGCAGCGCGTGTTTCTCGCGCGGGCCTTGGTGCAG
GACGCGGATCTTTACTTCATGGATGAGCCATTTCAAGGTGTGGATGCAGCTACTGAACAAGCAATCGTTACTCTTTTAAA
AACGCTGAAAGGGCGTGGGAAAACGTTGCTTGTTGTGCATCATGATTTGCAGACGGTGGCAGAGTATTTTGACCGCGTGC
TGCTTTTAAATGTTCGCGTCATCGCTGAAGGGGCCGTCGTGTCTGCCTTCACCGAAGAATACGTTCAAAGAGCCTATGGC
GGACGGATTAGTTCCACCCTTTTTCCGAGAGGAAATAAGGAGGATGTGCACGATGCACGCGCTCATGCGTCTGTTCTCTG
A

Protein sequence : 
MAEISATAYAVQVDDLTLAYRQKPVLWDVDVRIPEGVIEAIIGPNGAGKSTLLKAIMGLLPLASGEVRVFGRPFSKERRR
VAYVPQRSAVDWDFPTTVFDVVLMGSYGLLGWIRRPGKREKARAREAIEEVGMGAFLDRQISELSGGQQQRVFLARALVQ
DADLYFMDEPFQGVDAATEQAIVTLLKTLKGRGKTLLVVHHDLQTVAEYFDRVLLLNVRVIAEGAVVSAFTEEYVQRAYG
GRISSTLFPRGNKEDVHDARAHASVL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
EF0575 NP_814340.1 cationic ABC transporter ATP-binding protein Not tested Not named Protein 2e-37 46
ef0093 AAM75296.1 EF0093 Not tested Not named Protein 2e-37 46
sitB NP_461783.1 ATP-binding protein Virulence SPI-1 Protein 2e-41 42
sitB YP_217782.1 iron transporter: fur regulated Virulence SPI-1 Protein 1e-41 42
sitB AAD41066.1 SitB Virulence centisome 63 pathogenicity island Protein 1e-41 42
sitB NP_457256.1 Iron transport protein, ATP-binding component Virulence SPI-1 Protein 2e-40 41
sitB NP_806465.1 iron ABC transporter ATP-binding protein Virulence SPI-1 Protein 2e-40 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
troB YP_005229955.1 iron (Fe2+)/zinc (Zn2+)/manganese (Mn2+) ABC superfamily ATP binding cassette transporter, ABC protein BAC0400 Protein 9e-105 99
troB YP_005229955.1 iron (Fe2+)/zinc (Zn2+)/manganese (Mn2+) ABC superfamily ATP binding cassette transporter, ABC protein BAC0440 Protein 9e-39 43
troB YP_005229955.1 iron (Fe2+)/zinc (Zn2+)/manganese (Mn2+) ABC superfamily ATP binding cassette transporter, ABC protein BAC0350 Protein 8e-42 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
troB YP_005229955.1 iron (Fe2+)/zinc (Zn2+)/manganese (Mn2+) ABC superfamily ATP binding cassette transporter, ABC protein VFG0526 Protein 7e-42 42