Gene Information

Name : KPHS_05400 (KPHS_05400)
Accession : YP_005224840.1
Strain : Klebsiella pneumoniae HS11286
Genome accession: NC_016845
Putative virulence/resistance : Unknown
Product : putative P4-type integrase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 581952 - 583214 bp
Length : 1263 bp
Strand : +
Note : -

DNA sequence :
ATGAAGCTCAACGCCAGGCAGGTAGAGACCGCAAAGCCCAAAGACAAAACCTACAAAATGGCTGATGGCGGCGGTTTGTA
TCTCGAAGTTTCGGCTAAGGGGTCTAAATACTGGCGCATGAAATACAGACGCCCCTCTGACAAAAAAGAGGATCGCCTTG
CTTTTGGTGTTTGGCCAACTGTGACGCTTGCTCAGGCAAGAACCAAGCGCGACGAAGCTAAAAAGCTGTTAGTACAGGGC
ATTGACCCAAAAGCCGAACAGAAAGAAGCTCAGGCCGAGAATTCGGGGGCATATACTTTCGAAACAATTGCTCGCGAATG
GCATGCCAGTAACAAGCGATGGAGTGAAGACCATCGATCGCGCGTTCTTCGCTATCTTGAGCTTTATATCTTCCCTCATA
TCGGTTCGTCCGACATTCGCCAGCTCAAAACCAGCCACCTGTTAGCCCCGATTAAAAAAGTTGATGCCAGTGGCAAACAT
GACGTCGCGCAGCGTCTTCAGCAGCGTGTAACGGCCATTATGCGCTATGCCGTTCAGAACGATTACATAGACTCAAACCC
GGCCAGTGATATGGCTGGTGCTTTATCAACAACCAAAGCAAGACACTATCCAGCTTTACCCTCTAGCCGTTTCCCTGAAT
TTCTTGCTCGTCTGGCGGCATATCGTGGTCGTGTAATGACACGGATCGCCGTAGAGCTTTCATTGCTCACTTTTGTACGT
TCCAGTGAACTCCGTTTTGCACGTTGGGATGAATTCGATTTTGCTAAATCTCTTTGGCGTATACCTGCAAAGCGTGAAGA
AATTAAAGGCGTACGTTACTCCTACCGCGGCATGAAGATGAAAGAGGAACATATAGTTCCGCTTAGTCGACAAGCTATAG
TGTTGTTAGAGCAGCTTAAGCAAATCAGTGGTGATAAAGAGCTACTTTTTCCGGGAGATCACGACGCAACGAAGGTCATG
AGTGAAAACACAGTAAACGGTGCGTTGCGTGCTATGGGCTATGATACGAAAACAGAGGTCTGTGGGCATGGATTCAGGAC
GATGGCGCGCGGCGCGCTGGGGGAATCGGGTTTATGGAGTGATGATGCTATAGAACGCCAACTGAGTCATTCAGAGCGTA
ATAATGTACGTGCAGCATATATTCACACTTCTGAACATTTAGATGAACGCCGTTTAATGGTGCAATGGTGGGCTGATTAT
CTCAAATCAAATGAAGGCAAAATAGTCACACCTTATGAATTTGCCAAAATAAGAAAAAGCTGA

Protein sequence :
MKLNARQVETAKPKDKTYKMADGGGLYLEVSAKGSKYWRMKYRRPSDKKEDRLAFGVWPTVTLAQARTKRDEAKKLLVQG
IDPKAEQKEAQAENSGAYTFETIAREWHASNKRWSEDHRSRVLRYLELYIFPHIGSSDIRQLKTSHLLAPIKKVDASGKH
DVAQRLQQRVTAIMRYAVQNDYIDSNPASDMAGALSTTKARHYPALPSSRFPEFLARLAAYRGRVMTRIAVELSLLTFVR
SSELRFARWDEFDFAKSLWRIPAKREEIKGVRYSYRGMKMKEEHIVPLSRQAIVLLEQLKQISGDKELLFPGDHDATKVM
SENTVNGALRAMGYDTKTEVCGHGFRTMARGALGESGLWSDDAIERQLSHSERNNVRAAYIHTSEHLDERRLMVQWWADY
LKSNEGKIVTPYEFAKIRKS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY4821 NP_458899.1 integrase Not tested SPI-10 Protein 0.0 96
intB CAD42017.1 bacteriophage P4 integrase Not tested PAI II 536 Protein 2e-113 58
APECO1_3534 YP_854214.1 P4-like integrase Not tested PAI I APEC-O1 Protein 2e-117 55
ORF_1 AAZ04412.1 phage integrase Not tested PAI I APEC-O1 Protein 1e-117 55
S4822 NP_838459.1 P4-type integrase Not tested SHI-1 Protein 9e-118 55
SF2964 NP_708738.1 P4-type integrase Not tested SHI-1 Protein 9e-118 55
int AAK00456.1 Int Not tested SHI-1 Protein 2e-110 55
int AAK16198.1 Int Not tested PAI-I AL862 Protein 5e-118 55
int ADD91747.1 P4 integrase Not tested PAI-I AL862 Protein 5e-118 55
SESS1635_03816 AFO66367.1 bacteriophage integrase Not tested SESS LEE Protein 1e-113 55
SESS1296_03598 AFO66301.1 bacteriophage integrase Not tested SESS LEE Protein 1e-113 55
ECO111_3718 YP_003236059.1 putative integrase Not tested LEE Protein 4e-116 54
int NP_458759.1 bacteriophage integrase Not tested SPI-7 Protein 8e-111 54
int NP_807963.1 bacteriophage integrase Not tested SPI-7 Protein 8e-111 54
c5216 NP_757064.1 prophage P4 integrase Not tested PAI II CFT073 Protein 8e-118 54
ECUMN_3322 YP_002414004.1 integrase Not tested Not named Protein 3e-117 54
int AAT48697.1 CP4-like integrase Not tested PAI I 4787 Protein 4e-117 54
ECO103_3550 YP_003223418.1 integrase Not tested LEE Protein 1e-117 54
int AAL51003.1 CP4-like integrase Not tested LEE Protein 4e-117 54
ECO26_5300 YP_003232178.1 integrase Not tested LEE Protein 1e-117 54
int-phe AAL57571.1 CP4-like integrase Not tested LEE Protein 1e-117 54
int AAL51028.1 CP4-like integrase Not tested LEE Protein 1e-117 54
c3556 NP_755431.1 prophage P4 integrase Not tested PAI I CFT073 Protein 6e-117 54
int-phe AAL60261.1 Int-phe Not tested LEE Protein 1e-117 54
intP4 CAE85151.1 CP4 integrase protein Not tested PAI V 536 Protein 7e-118 54
int CAC81896.1 integrase Not tested LEE II Protein 3e-110 54
Z4313 NP_289539.1 pathogenicity island integrase Not tested OI-122 Protein 6e-117 53
APECO1_1051 YP_853069.1 phage integrase Not tested PAI IV APEC-O1 Protein 8e-76 51
intB AAD37509.1 P4-like integrase Not tested PAI IV 536 Protein 5e-87 50
y2393 NP_669700.1 prophage integrase Not tested HPI Protein 3e-99 49
int2 NP_993013.1 integrase Not tested HPI Protein 3e-99 49
int CAA21384.1 - Not tested HPI Protein 3e-99 49
int CAB59974.1 integrase Not tested HPI Protein 1e-99 49
int CAA08754.1 integrase Not tested HPI Protein 8e-100 49
int YP_002346908.1 integrase Not tested HPI Protein 3e-99 49
unnamed ABR13507.1 phage integrase Not tested PAGI-6 Protein 1e-93 49
unnamed AAD17660.1 unknown Not tested HPI Protein 4e-96 48
int AAD44730.1 Int Not tested SHI-2 Protein 2e-75 44
aec33 AAW51716.1 Int Not tested AGI-3 Protein 8e-76 44
int CAC39282.1 integrase Not tested LPA Protein 8e-76 44
int AAD54663.1 Sai integrase Not tested SHI-2 Protein 1e-74 44
S4835 NP_839238.1 integrase Not tested SHI-2 Protein 1e-74 44
SF3698 NP_709437.1 integrase Not tested SHI-2 Protein 1e-74 44
ESA_03025 YP_001439090.1 hypothetical protein Not tested Not named Protein 1e-73 43
int AAC31482.1 CP4-like integrase Not tested LEE Protein 1e-73 43
int ACU09430.1 integrase Not tested LEE Protein 1e-73 43
intL NP_290239.1 integrase for prophage 933L and the LEE pathogenicity island Not tested LEE Protein 1e-73 43
ECs4534 NP_312561.1 integrase Not tested LEE Protein 1e-73 43
unnamed AFX83955.1 integrase Not tested SE-PAI Protein 1e-72 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
KPHS_05400 YP_005224840.1 putative P4-type integrase VFG1536 Protein 1e-113 58
KPHS_05400 YP_005224840.1 putative P4-type integrase VFG0626 Protein 4e-118 55
KPHS_05400 YP_005224840.1 putative P4-type integrase VFG1693 Protein 3e-117 54
KPHS_05400 YP_005224840.1 putative P4-type integrase VFG0598 Protein 6e-75 44
KPHS_05400 YP_005224840.1 putative P4-type integrase VFG0783 Protein 6e-74 43