Gene Information

Name : KPHS_45980 (KPHS_45980)
Accession : YP_005228898.1
Strain : Klebsiella pneumoniae HS11286
Genome accession: NC_016845
Putative virulence/resistance : Virulence
Product : urease subunit alpha
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 4620104 - 4621807 bp
Length : 1704 bp
Strand : +
Note : -

DNA sequence :
ATGAGTAATATTTCACGCCAGGCCTATGCCGATATGTTCGGCCCCACCGTCGGCGACAAGGTGCGCCTGGCGGATACCGA
GCTGTGGATCGAGGTGGAGGACGATCTGACCACCTACGGGGAAGAGGTCAAATTCGGCGGCGGCAAAGTGATCCGCGACG
GCATGGGCCAGGGGCAGATGCTGGCCGCCGACTGTGTCGACCTGGTGCTCACCAACGCGTTGATCGTCGATCACTGGGGG
ATCGTTAAGGCCGATATCGGCGTGAAGGACGGCCGGATCTTCGCCATCGGCAAAGCCGGTAACCCCGACATCCAGCCCAA
CGTCACCATCCCCATCGGTGCCTCGACGGAAGTGATTGCCGCCGAAGGAAAAATTGTCACCGCCGGCGGGATCGATACCC
ATATTCACTGGATCTGTCCGCAGCAGGCGGAAGAGGCGCTGGTCTCCGGCGTGACCACCATGGTCGGCGGCGGCACCGGC
CCGGCCGCGGGCACCCATGCCACCACCTGCACCCCGGGCCCGTGGTATATCTCACGCATGCTGCAGGCGGCCGACAGCCT
GCCGGTCAATATCGGCCTGCTGGGCAAGGGCAACGTTTCTCAGCCGGATGCCCTGCGCGAGCAGGTGGCGGCGGGCGTTA
TTGGCCTGAAGATCCATGAGGACTGGGGCGCCACCCCGGCGGCGATCGATTGTGCGTTAACCGTCGCCGATGAAATGGAC
ATCCAGGTCGCCCTGCACAGCGACACCCTGAATGAATCCGGTTTTGTGGAAGACACCCTCGCCGCCATCGGCGGGCGCAC
CATCCACACCTTCCATACCGAAGGGGCCGGCGGCGGCCATGCGCCAGACATCATCACCGCCTGCGCCCACCCGAACATTT
TGCCGTCGTCCACCAACCCAACGCTGCCCTACACCCTCAACACCATCGATGAACATCTCGATATGCTGATGGTCTGCCAC
CATCTGGACCCGGACATCGCTGAGGACGTGGCCTTTGCCGAGTCGCGCATTCGCCGGGAAACCATCGCTGCGGAAGACGT
GCTGCACGATCTCGGCGCCTTCTCGCTCACCTCCTCCGATTCGCAGGCCATGGGCCGCGTCGGGGAAGTGATTCTCCGCA
CCTGGCAGGTGGCGCATCGCATGAAGGTGCAGCGCGGAGCGCTGGCGGAGGAGACCGGGGATAACGACAACTTCCGCGTG
AAGCGCTACATCGCCAAATACACCATCAACCCGGCGCTGACCCACGGCATCGCACACGAAGTCGGATCCATTGAGGTGGG
TAAGCTGGCTGACCTCGTGGTCTGGTCACCAGCCTTCTTCGGCGTGAAACCGGCCACCGTGATCAAAGGCGGCATGATCG
CCATCGCGCCGATGGGCGATATCAATGCCTCTATTCCGACCCCGCAGCCGGTGCACTACCGCCCGATGTTTGGCGCGCTG
GGCAGCGCCCGCCATCACTGCCGCCTCACCTTCCTGTCGCAGGCGGCGGCAGCCAATGGCGTTGCCGAGCGGCTGAACCT
GCGCAGCGCGATCGCCGTGGTGAAAGGCTGCCGTACGGTGCAGAAAGCCGACATGGTGCACAACAGCCTGCAGCCTAACA
TCACCGTCGACGCCCAGACCTATGAGGTGCGGGTGGATGGCGAACTTATCACCAGCGAGCCGGCAGACGTTCTGCCGATG
GCGCAACGATATTTTCTGTTTTAA

Protein sequence :
MSNISRQAYADMFGPTVGDKVRLADTELWIEVEDDLTTYGEEVKFGGGKVIRDGMGQGQMLAADCVDLVLTNALIVDHWG
IVKADIGVKDGRIFAIGKAGNPDIQPNVTIPIGASTEVIAAEGKIVTAGGIDTHIHWICPQQAEEALVSGVTTMVGGGTG
PAAGTHATTCTPGPWYISRMLQAADSLPVNIGLLGKGNVSQPDALREQVAAGVIGLKIHEDWGATPAAIDCALTVADEMD
IQVALHSDTLNESGFVEDTLAAIGGRTIHTFHTEGAGGGHAPDIITACAHPNILPSSTNPTLPYTLNTIDEHLDMLMVCH
HLDPDIAEDVAFAESRIRRETIAAEDVLHDLGAFSLTSSDSQAMGRVGEVILRTWQVAHRMKVQRGALAEETGDNDNFRV
KRYIAKYTINPALTHGIAHEVGSIEVGKLADLVVWSPAFFGVKPATVIKGGMIAIAPMGDINASIPTPQPVHYRPMFGAL
GSARHHCRLTFLSQAAAANGVAERLNLRSAIAVVKGCRTVQKADMVHNSLQPNITVDAQTYEVRVDGELITSEPADVLPM
AQRYFLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 0.0 92
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 0.0 92
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 4e-166 64
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 3e-166 64
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 3e-166 64
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 3e-166 64

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
KPHS_45980 YP_005228898.1 urease subunit alpha VFG0270 Protein 1e-153 62