Gene Information

Name : KPHS_43720 (KPHS_43720)
Accession : YP_005228672.1
Strain : Klebsiella pneumoniae HS11286
Genome accession: NC_016845
Putative virulence/resistance : Resistance
Product : Ars family arsenical pump
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 4408595 - 4409887 bp
Length : 1293 bp
Strand : -
Note : -

DNA sequence : 
ATGTTGCTGGCAGGTACGATTTTTATCCTGACCCTGGTGCTGGTGATCTGGCAGCCGCGGGGGTTAGGGATCGGCTGGAG
CGCGGCATTTGGCGCGGCGCTGGCGCTGGCCACCGGTGGCGTACAGGTAGCCGATATCCCGGTGGTATGGCATATCGTCT
GGAATGCGACCGCCACCTTTATCGCCGTTATCATTATCAGCCTGCTGCTTGATGAGTCTGGCTTTTTCGAATGGGCCGCG
CTGCACGTTTCCCGCTGGGGAAGAGGCCGGGGTCGTCTGCTGTTTACCTGGATTATCCTGCTCGGCGCGGCTGTGGCGGC
GCTGTTTGCCAACGATGGGGCGGCGCTGATCCTCACGCCAATCGTGATTGCCATGCTGCGAGCGCTGGGGTTCAGCAAGG
GAACGATGCTGGCCTTTGTCATGGCCGCCGGATTTATTGCCGATACCGCCAGCCTGCCGCTGGTGGTGTCGAATCTGGTG
AATATCGTTTCGGCAGATTTCTTTGCCATCGGCTTCAGGGAGTACGCTTCGGTGATGGTGCCGGTCGATCTCGCGGCGAT
CCTCACCACCCTGGCGATGCTGCACCTGTTCTTTCGCAAGGATATCCCGCCGGCCTGGGATATGGCGTTACTAAAAGCGC
CGGCCACGGCGATAAAAGATCCAGCGACGTTCCGCACCGGCTGGGGCGTGCTGCTGCTGTTGCTGGCTGGCTTTTTCGTC
CTTGAACCGCTGGGGATCCCGGTCAGCGCCATCGCGGCGCTCGGCGCCGGGATCCTGTTTGCTGTCGCGAAGCGCGGGCG
GGTAATTAACACCGGCAAGGTGCTGCGCGGCGCCCCGTGGCAGATAGTGATCTTCTCGCTGGGAATGTATCTGGTGGTGT
ATGGTCTGCGAAACGCCGGGTTAACGGATTATCTGACCACGGTGCTGAACATGCTGGCGGAGCGCGGCCTCTGGGCCGCG
ACGCTGGGCACCGGTATCCTGTCGGCCTTCCTCTCTTCAATAATGAATAATATGCCCAGCGTACTGGTCGGCGCCCTGTC
GATTGATGGCAGCACGGCAACAGGGACGATCAAAGAGGCCATGATTTATGCCAACGTCATCGGCTGCGATCTGGGGCCCA
AGATCACGCCAATTGGTAGCCTGGCCACGCTGCTGTGGCTGCATGTGCTGGCGCAGAAGCACATCACCATCGGTTGGGGG
TATTATTTCCGCTGCGGCATCACCATGACCCTGCCGGTGCTGCTTGTGACGCTGGCCGCGCTGGCGCTGCGTCTCTCCTT
CAACCAGCCATGA

Protein sequence : 
MLLAGTIFILTLVLVIWQPRGLGIGWSAAFGAALALATGGVQVADIPVVWHIVWNATATFIAVIIISLLLDESGFFEWAA
LHVSRWGRGRGRLLFTWIILLGAAVAALFANDGAALILTPIVIAMLRALGFSKGTMLAFVMAAGFIADTASLPLVVSNLV
NIVSADFFAIGFREYASVMVPVDLAAILTTLAMLHLFFRKDIPPAWDMALLKAPATAIKDPATFRTGWGVLLLLLAGFFV
LEPLGIPVSAIAALGAGILFAVAKRGRVINTGKVLRGAPWQIVIFSLGMYLVVYGLRNAGLTDYLTTVLNMLAERGLWAA
TLGTGILSAFLSSIMNNMPSVLVGALSIDGSTATGTIKEAMIYANVIGCDLGPKITPIGSLATLLWLHVLAQKHITIGWG
YYFRCGITMTLPVLLVTLAALALRLSFNQP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
arsB2 YP_001007633.1 arsenical pump membrane protein Not tested YAPI Protein 3e-145 86
arsB YP_252017.1 arsenical pump membrane protein Not tested SCCmec Protein 8e-98 58
arsB YP_005754065.1 arsenical pump membrane protein Not tested Type-XI SCCmec Protein 5e-96 56
SH0109 YP_252024.1 arsenical pump membrane protein Not tested SCCmec Protein 2e-97 56

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
KPHS_43720 YP_005228672.1 Ars family arsenical pump BAC0578 Protein 1e-146 87
KPHS_43720 YP_005228672.1 Ars family arsenical pump BAC0031 Protein 1e-144 86
KPHS_43720 YP_005228672.1 Ars family arsenical pump BAC0576 Protein 7e-146 86
KPHS_43720 YP_005228672.1 Ars family arsenical pump BAC0577 Protein 7e-144 84
KPHS_43720 YP_005228672.1 Ars family arsenical pump BAC0574 Protein 5e-97 57
KPHS_43720 YP_005228672.1 Ars family arsenical pump BAC0575 Protein 6e-98 56