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Name : clpA1 (TPEGAU_0549) Accession : YP_005222733.1 Strain : Treponema pallidum Gauthier Genome accession: NC_016843 Putative virulence/resistance : Virulence Product : S14 family endopeptidase ClpA Function : - COG functional category : - COG ID : - EC number : - Position : 595146 - 597590 bp Length : 2445 bp Strand : + Note : ATP-dependent Clp protease, ATP-binding subunit ClpA DNA sequence : GTGTTACAGGACCTATCCGCAAATGCCCGTAAGGTACTGCTCGAGCTCGGTCAGACCGTTGCGCGTGAGGCTCGCGCCTC GCTCCTTCAGCCAGAGCACATTCTGCTCGCCCTCATTCAGCACAAAGTAGGCTGCGGCTACAAGCTCATCGAAAAACTCA TTGAAGATGTCGCTACCGTCCGCCTCATCCTCGAGCAACACGTCCTTACCAATGAGGGAGACGTCGCCAGTCCCCAGGAC CTGCCCGTCTCAGGACGCGTCAAACACTTGCTCGACATCGCAGCAATGGAAGCACGCTCCCTGCGGTGCGCTTACATCGG TACCGAACACCTCGTTATCGCCTTTGCCCGAGAGGAGCAAAATCCTCTCTTCCAAAGCCTCATCCGAGAAGGACTCTCGC TCGATGACCTGCGAAACGCGAGCATTATATCCTCACCTCATTCTGATACCACCCGCACCCGGCTCGAGCGGAAAGTTGCA AGTGTCCTTGACGAATACGGCACCGACCTTACCGAACGCGCGCGCGCCGGCGCCCTCAATCCGGTCATCGGACGAAACAA AGAAATTACCCGCGTCATTCAAATCCTGTGCCGGAGAGGAAAAAATAACCCGGTGCTCATCGGAGAGCCAGGTGTCGGGA AAACTTCCATCGTTGAGGGGCTCGCGTACGCCATCGTTCGGGAGGAGGTCCCGCACATCCTGCTGCACACCCGCGTCGTT TCCCTAGACCTTGCCGCCGTCATAGCAGGAACAAAGTACCGCGGCCAGTTTGAGGAGCGGCTCAAACGCATTATTAAGGA GGTGGAAGAAACTGAAAAAGTCATCCTTTTCATCGATGAGCTGCACACACTCATCGGAGCAGGAGGCACGCAGGGGTCTT TGGACGCCGCCAACATGCTCAAGCCGGCCCTTGCACGCGGACAAATCCAGTGCATTGGGGCAACAACCCTGGCAGAGTAT CGCCGTTACTTTGAAAAAGACGCAGCTCTCACCCGCCGATTCCGATCGGTGCTCGTGCGTGAACCGAGCTTTGAAGAAAC CTGCACTATTTTACGCAAAATAAAATCACACTACGAACGACATCACCAGGTGATATACCAAAGCGATGCGCTTGAAAAAA TTGTTGAGCTTTCACGGCGCTACATCCCTGAGCGGTTCTTTCCAGATAAGGCAATTGATCTTATGGATGAAGTAGGAGCC ATGAAACGGGTACAACAGCGCGCGGATACGCAGGTATTGCGTTCCTTTTCCATAAAAGTTGCTAATCTTACCACAGAGAC TGAGCGCGCCATTGCGCTTGAAGATTGGGCGCGCGCGCGTTCCTTACACACCGATGTGGTGCAGCTGCGCAGACGGCTCC ACGCGCTGAAGGTAGAGTGGAGCGCGCGCGAAGCGCTGTCTATCTTTGCAGAAGATGTTGCACAGGCTGTCTCTCTCATG ACCGATATCCCGGTACATTCGCTCGAAGGGGATGAGCTGTGCCGCTTTACCAATATCGAACGGGATCTTTGTGCCACCGT GCGTGGGCAGCGCGAGGCCATTGCAACGCTCGCGCGCGCTATCGTACGCGCGCGTGTCGGCATCTCTTCAGACACGCGCC CCATTGGCTCCTTCCTGTTTCTTGGACCGACCGGTGTAGGCAAAACGCTCTTGGCAAAGACACTCGCGGAATTTCTTTTC GGTTCAGCAGACGCGCTCATCCGCATTGACATGAGCGACTACATGGAACGCTACAACACCTCACGCCTCATGGGAGCACC GCCTGGATACGTGGGATTTGAAAATGGCGGTCTACTTACCGAGCGCGTACGGCACCGCCCTTTTTCTGTCATCCTTCTGG ATGAAATTGAAAAGGCGCATCCAGATGTCTTCAATGTTCTCCTCCAGGTGTTAGAAGAAGGAGAGCTGCAAGACAACCTG GGGCACACGGTGAACTTCCGCAACACTATCATCATCATGACCAGCAATGCAGGCACACGCGGCCTGGGGGAAAACGTTCC TGGCTTTCAAACCGCACGCGCGCGAAACATCGAGTACCGTCAGCTGCGCGTACAGGCCCTCCGGGAAATAAAACGCATCT TCTCTCCGGAGTTTCTCAATCGCGTTGACGAGTGCGTAGTGTTTGCTCCGCTTGAGCGAGAGACCCTGCAGGAAATTTTA GAATGCGAACTGAAGAAGCTCGCAGAACGCCTACGCGGTAAAGATATTGTGCTGCGCTACAGCGCGGCTGCAAAGGCCTA CTGTCTTGAACACGGCTTTGACCCATTCTTGGGCGCACGCCCCCTGCGCCGCGTATTGCAGCAAGAAATTGAAAATGAGC TTGCGCTGCGCATGATTCACGGAACGTTGCGCGCAGGATCGTGCGTGCACATAGACTCAGACGGCGCGCGCCTCCACCTT TCTACCGAAAAAAGTTACCTGACGCTGCATCCCCAAGAAATATAA Protein sequence : MLQDLSANARKVLLELGQTVAREARASLLQPEHILLALIQHKVGCGYKLIEKLIEDVATVRLILEQHVLTNEGDVASPQD LPVSGRVKHLLDIAAMEARSLRCAYIGTEHLVIAFAREEQNPLFQSLIREGLSLDDLRNASIISSPHSDTTRTRLERKVA SVLDEYGTDLTERARAGALNPVIGRNKEITRVIQILCRRGKNNPVLIGEPGVGKTSIVEGLAYAIVREEVPHILLHTRVV SLDLAAVIAGTKYRGQFEERLKRIIKEVEETEKVILFIDELHTLIGAGGTQGSLDAANMLKPALARGQIQCIGATTLAEY RRYFEKDAALTRRFRSVLVREPSFEETCTILRKIKSHYERHHQVIYQSDALEKIVELSRRYIPERFFPDKAIDLMDEVGA MKRVQQRADTQVLRSFSIKVANLTTETERAIALEDWARARSLHTDVVQLRRRLHALKVEWSAREALSIFAEDVAQAVSLM TDIPVHSLEGDELCRFTNIERDLCATVRGQREAIATLARAIVRARVGISSDTRPIGSFLFLGPTGVGKTLLAKTLAEFLF GSADALIRIDMSDYMERYNTSRLMGAPPGYVGFENGGLLTERVRHRPFSVILLDEIEKAHPDVFNVLLQVLEEGELQDNL GHTVNFRNTIIIMTSNAGTRGLGENVPGFQTARARNIEYRQLRVQALREIKRIFSPEFLNRVDECVVFAPLERETLQEIL ECELKKLAERLRGKDIVLRYSAAAKAYCLEHGFDPFLGARPLRRVLQQEIENELALRMIHGTLRAGSCVHIDSDGARLHL STEKSYLTLHPQEI |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| clpC | YP_005163377.1 | ATP-dependent Clp protease ATP-binding subunit | Not tested | Not named | Protein | 4e-149 | 42 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| clpA1 | YP_005222733.1 | S14 family endopeptidase ClpA | VFG0080 | Protein | 9e-134 | 50 |
| clpA1 | YP_005222733.1 | S14 family endopeptidase ClpA | VFG0079 | Protein | 2e-163 | 44 |
