Gene Information

Name : SSON53_18280 (SSON53_18280)
Accession : YP_005458160.1
Strain : Shigella sonnei 53G
Genome accession: NC_016822
Putative virulence/resistance : Virulence
Product : serine protease
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 3430127 - 3433984 bp
Length : 3858 bp
Strand : +
Note : 'COG3468 Type V secretory pathway, adhesin AidA'

DNA sequence :
ATGAATAAAATTTATTCACTGAAATATAGTCATATTACAGGTGGATTAGTTGCTGTTTCTGAACTGACCCGGAAAGTTAG
TGTCGGTACATCAAGAAAGAAAGTTATCCTCGGTATTATTTTATCCTCAATATATGGAAGTTATGGCGAAACAGCATTTG
CAGCAATGCTGGATATAAATAATATATGGACCCGCGATTATCTTGACCTTGCTCAAAACAGAGGAGAGTTCAGACCGGGT
GCAACAAATGTTCAATTAATGATGAAAGATGGAAAGATATTTCATTTTCCAGAACTACCTGTACCTGATTTTTCTGCTGT
TTCCAACAAAGGTGCAACAACATCAATTGGAGGTGCGTACAGTGTTACTGCGACTCATAACGGTACACAGCATCATGCAA
TAACAACACAGTCATGGGATCAGACAGCATATAAAGCAAGTAACAGAGTATCATCTGGCGACTTTTCGGTTCATCGTCTG
AATAAATTCGTCGTGGAAACAACAGGGGTTACGGAGAGTGCCGACTTCTCACTTTCTCCCGAAGATGCGATGAAAAGATA
TGGCGTAAACTACAACGGTAAGGAACAAATAATTGGCTTCAGAGCAGGTGCCGGAACAACCTCAACGATATTAAACGGCA
AACAATATCTGTTTGGACAAAACTATAATCCCGACTTGTTAAGCGCAAGTCTTTTTAATCTGGACTGGAAAAACAAGAGT
TACATTTATACCAACAGAACCCCTTTTAAAAACTCACCAATTTTTGGCGATAGTGGTTCTGGTTCTTATCTATATGATAA
AGAACAACAAAAATGGGTTTTCCATGGTGTTACCAGTACAGTTGGTTTTCTCAGTAGTACCAATATAGCCTGGACAAACT
ACTCGTTATTTAATAATATTCTGGTAAACAATTTAAAAAAGAATTTCACAAACACTATGCAGCTGGATGGTAAAAAACAA
GAGTTATCATCGATTATAAAAGATAAGGACCTGTCTGTCTCAGGAGGAGGGGAATTAACGCTCAAGCAGGATACCGATCT
TGGCATTGGCGGGCTTATATTCGATAAGAACCAGACATATAAAGTGTACGGAAAAGATAAGTCTTATAAAGGTGCCGGGA
TAGATATTGATAATAATACCACCGTTGAATGGAATGTTAAGGGCGTTGCCGGAGATAATCTGCATAAAATAGGTAGTGGT
ACTCTGGATGTAAAAATAGCACAGGGAAATAACCTTAAAATAGGTAATGGGACTGTCATCCTTAGTGCTGAAAAAGCCTT
CAATAAAATTTACATGGCCGGAGGTAAAGGTACGGTAAAAATAAATGCCAAAGACGCTTTAAGCGAAAGCGGTAATGGCG
AAATCTATTTTACCAGAAATGGCGGAACACTGGATCTAAACGGCTATGACCAGTCATTTCAGAAAATCGCAGCAACAGAT
GCGGGAACAACCGTAACGAACTCAAACGTGAAGCAATCAACATTATCACTTACTAATACTGATGCATATATGTACCATGG
GAATGTATCAGGTAATATAAGCATAAATCATATTATCAATACTACCCAGCAACATAACAATAATGCCAATCTGATCTTTG
ATGGCTCAGTCGATATCAAAAACGATATCTCTGTCCGGAATGCACAGTTAACATTACAAGGACATGCGACAGAACATGCC
ATATTTAAAGAAGGCAATAACAACTGTCCAATTCCTTTTTTATGTCAAAAAGACTATTCTGCTGCCATAAAGGACCAGGA
AAGCACTGTAAATAAACGTTACAATACGGAATATAAGTCCAACAATCAGATAGCCTCTTTTTCCCAGCCCGACTGGGAAA
GTCGTAAATTTAATTTCCGGAAATTAAATTTAGAAAACGCAACCCTGAGTATAGGCCGGGATGCTAATGTAAAAGGACAC
ATAGAGGCTAAAAACTCTCAAATTGTTCTGGGAAATAAAACTGCATACATTGACATGTTCTCAGGAAGAAACATTACTGG
CGAAGGTTTTGGATTCAGACAACAGCTTCGCTCCGGGGATTCAGCAGGCGAAAGTAGTTTCAACGGCAGTCTGAGTGCTC
AAAACAGCAAAATAACTGTTGGTGATAAATCAACTGTTACTATGACTGGTGCATTATCCTTAATTAATACAGACCTGATT
ATCAACAAAGGAGCTACTGTTACCGCCCAGGGAAAAATGTATGTAGATAAAGCTATTGAACTGGCCGGAACCCTGACATT
AACAGGCACCCCTACAGAAAATAATAAATACAGCCCGGCAATCTATATGTCAGATGGATATAATATGACAGAAGATGGTG
CCACGTTAAAGGCTCAAAATTATGCCTGGGTCAATGGTAATATAAAATCAGACAAAAAAGCATCTATTCTGTTTGGTGTT
GACCAGTATAAAGAAGATAACCTGGACAAAACCACACACACACCGCTGGCTACAGGTTTGCTGGGTGGCTTTGATACTTC
TTATACCGGAGGTATTGATGCTCCTGCTGCCTCAGCCAGCATGTATAACACCTTATGGAGAGTAAACGGACAGTCAGCCC
TGCAATCATTAAAAACCCGCGACAGTCTTTTGTTGTTTAGTAACATAGAGAATTCGGGTTTCCATACTGTGACAGTAAAC
ACACTGGATGCCACTAATACTGCTGTGATTATGCGGGCTGATCTGAGCCAGTCTGTAAATCAATCGGATAAACTCATTGT
TAAAAATCAGTTAACCGGAAGCAATAACAGTCTGTCGGTCGATATACAGAAAGTGGGAAATAATAACTCAGGATTAAACG
TTGACCTGATAACAGCCCCAAAAGGAAGCAATAAAGAGATATTTAAAGCCAGTACTCAGGCCATAGGTTTCAGCAACATA
TCTCCTGTGATCAGCACGAAAGAGGATCAGGAACATACCACGTGGACCCTGACCGGATATAAGGTGGCTGAAAATACAGC
ATCTTCCGGTGCAGCAAAATCGTATATGTCCGGTAATTACAAAGCCTTCCTGACAGAAGTCAACAACCTGAATAAACGAA
TGGGGGATCTGCGTGACACCAATGGCGAGGCCGGTGCATGGGCCCGCATCATGAGCGGAGCAGGTTCAGCTTCTAGTGGA
TACAGTGACAACTACACCCATGTGCAGATTGGTGTGGATAAAAAACATGAGCTGGATGGACTTGACCTTTTCACTGGTCT
GACTATGACGTATACCGACAGTCATGCCAGCAGTAATGCATTCAGTGGCAAGACGAAGTCCGTCGGGGCAGGTCTGTATG
CTTCCGCTATATTTGACTCTGGTGCCTATATCGACCTGATTAGTAAGTATGTTCACCATGATAATGAGTACTCGGCGACC
TTTGCTGGACTCGGAACAAAAGACTACAGTTCTCATTCCTTGTATGTGGGTGCTGAAGCAGGCTACCGCTATCATGTAAC
AGAAGACTCCTGGATTGAGCCGCAGGCAGAACTGGTTTATGGGGCCGTATCAGGTAAACGGTTCGACTGGCAGGATCGCG
GAATGAGCGTGACCATGAAGGATAAGGACTTTAATCCGCTGATTGGGCGTACCGGTGTTGATGTGGGTAAATCCTTCTCC
GGTAAGGACTGGAAAGTCACAGCCCGCGCCGGCCTTGGCTACCAGTTTGACCTGTTTGCCAACGGTGAAACCGTACTGCG
TGATGCGTCCGGTGAGAAACGTATCAAAGGTGAAAAAGACGGTCGTATTCTCATGAATGTTGGTCTCAACGCCGAAATTC
GCGATAATCTTCGCTTCGGTCTTGAGTTTGAGAAATCGGCATTTGGTAAATACAACGTGGATAACGCGATCAACGCCAAC
TTCCGTTACTCTTTCTGA

Protein sequence :
MNKIYSLKYSHITGGLVAVSELTRKVSVGTSRKKVILGIILSSIYGSYGETAFAAMLDINNIWTRDYLDLAQNRGEFRPG
ATNVQLMMKDGKIFHFPELPVPDFSAVSNKGATTSIGGAYSVTATHNGTQHHAITTQSWDQTAYKASNRVSSGDFSVHRL
NKFVVETTGVTESADFSLSPEDAMKRYGVNYNGKEQIIGFRAGAGTTSTILNGKQYLFGQNYNPDLLSASLFNLDWKNKS
YIYTNRTPFKNSPIFGDSGSGSYLYDKEQQKWVFHGVTSTVGFLSSTNIAWTNYSLFNNILVNNLKKNFTNTMQLDGKKQ
ELSSIIKDKDLSVSGGGELTLKQDTDLGIGGLIFDKNQTYKVYGKDKSYKGAGIDIDNNTTVEWNVKGVAGDNLHKIGSG
TLDVKIAQGNNLKIGNGTVILSAEKAFNKIYMAGGKGTVKINAKDALSESGNGEIYFTRNGGTLDLNGYDQSFQKIAATD
AGTTVTNSNVKQSTLSLTNTDAYMYHGNVSGNISINHIINTTQQHNNNANLIFDGSVDIKNDISVRNAQLTLQGHATEHA
IFKEGNNNCPIPFLCQKDYSAAIKDQESTVNKRYNTEYKSNNQIASFSQPDWESRKFNFRKLNLENATLSIGRDANVKGH
IEAKNSQIVLGNKTAYIDMFSGRNITGEGFGFRQQLRSGDSAGESSFNGSLSAQNSKITVGDKSTVTMTGALSLINTDLI
INKGATVTAQGKMYVDKAIELAGTLTLTGTPTENNKYSPAIYMSDGYNMTEDGATLKAQNYAWVNGNIKSDKKASILFGV
DQYKEDNLDKTTHTPLATGLLGGFDTSYTGGIDAPAASASMYNTLWRVNGQSALQSLKTRDSLLLFSNIENSGFHTVTVN
TLDATNTAVIMRADLSQSVNQSDKLIVKNQLTGSNNSLSVDIQKVGNNNSGLNVDLITAPKGSNKEIFKASTQAIGFSNI
SPVISTKEDQEHTTWTLTGYKVAENTASSGAAKSYMSGNYKAFLTEVNNLNKRMGDLRDTNGEAGAWARIMSGAGSASSG
YSDNYTHVQIGVDKKHELDGLDLFTGLTMTYTDSHASSNAFSGKTKSVGAGLYASAIFDSGAYIDLISKYVHHDNEYSAT
FAGLGTKDYSSHSLYVGAEAGYRYHVTEDSWIEPQAELVYGAVSGKRFDWQDRGMSVTMKDKDFNPLIGRTGVDVGKSFS
GKDWKVTARAGLGYQFDLFANGETVLRDASGEKRIKGEKDGRILMNVGLNAEIRDNLRFGLEFEKSAFGKYNVDNAINAN
FRYSF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
sigA NP_838462.1 serine protease Virulence SHI-1 Protein 0.0 99
sigA NP_708742.1 serine protease Virulence SHI-1 Protein 0.0 99
sigA AAF67320.1 exported serine protease SigA Virulence SHI-1 Protein 0.0 99
sat YP_002414040.1 Serine protease Not tested Not named Protein 0.0 55
espC AAG37043.1 enterotoxin EspC Virulence espC PAI Protein 0.0 54
pic NP_838464.1 serine protease precurser Virulence SHI-1 Protein 2e-172 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SSON53_18280 YP_005458160.1 serine protease VFG0630 Protein 0.0 99
SSON53_18280 YP_005458160.1 serine protease VFG0862 Protein 0.0 56
SSON53_18280 YP_005458160.1 serine protease VFG0844 Protein 0.0 56
SSON53_18280 YP_005458160.1 serine protease VFG0902 Protein 0.0 55
SSON53_18280 YP_005458160.1 serine protease VFG0772 Protein 0.0 54