Gene Information

Name : SSON53_18230 (SSON53_18230)
Accession : YP_005458150.1
Strain : Shigella sonnei 53G
Genome accession: NC_016822
Putative virulence/resistance : Unknown
Product : P4-type integrase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 3419717 - 3420721 bp
Length : 1005 bp
Strand : +
Note : COG0582 Integrase

DNA sequence :
ATGGCACTGACTGACGCAAAAATCCGGGCTGCAAAGCCCACTGACAAGGCTTATAAACTCACTGACGGGGCTGGCATGTT
CCTGCTGGTACATCCTAATGGCTCCCGTTACTGGCGTCTCCGTTATCGTATTCTGGGTAAGGAGAAGACTCTGGCACTTG
GTGTGTATCCAGAAGTTTCTCTCTCCGAAGCTCGTACAAAACGGGATGAGGCCCGAAAACTGATTTCGGAGGGGGTTGAC
CCTTGCGAACAGAAAAGAGCTAAAAAAGTAGTCCCTGATTTACAGCTCTCTTTTGAACATATTGCGCGACGCTGGCATGC
CAGTAATAAACAATGGGCACAATCACACAGCAATAAAGTACTCAAAAGCCTTGAGACTCACGTTTTCCCCTTTATCGGCA
ACCGGGATATCACAACACTCAATACCCCGGATCTGCTTATCCCTGTTCGTGCTGCAGAAGCTAAACAAATTTATGAAATC
GCCAGTCGTCTGCAGCAAAGAATATCTGCCGTAATGCGTTATGCCGTACAGTCTGGCATCATCAGATATAATCCTGCTCT
GGATATGGCTGGCGCATTGACTACGGTAAAACGCCAGCATCGCCCCGCTCTTGATCTTTCTCGCCTGCCTGAACTTTTGT
CGCGTATTGGCAGTTACAAAGGGCAACCTGTCACCCAGCTTGCCGTTATGCTGAATTTACTGGTTTTTATTCGTTCCAGT
GAACTCAGATACGCCCGCTGGTCTGAAATTGATATTGACAATGCCATGTGGACTATTCCAGCCGAACGCGAACCCCTGCC
AGGCGTAAAATTCTCACACCGGGGCTCCAAGATGCGAACACCACATCTTGTGCCACTCAGCAAACAGGCTGTAGCCATAC
TGACAGAACTACAGACATGGGCTGGTGAAAATGGTCTGATCTTTACGGGAGCACATGACCCGCGTAAACCAATCAGTGAA
AATGTAATGAACGCATCCCACACAATTAAACACGGAGCAGTATGA

Protein sequence :
MALTDAKIRAAKPTDKAYKLTDGAGMFLLVHPNGSRYWRLRYRILGKEKTLALGVYPEVSLSEARTKRDEARKLISEGVD
PCEQKRAKKVVPDLQLSFEHIARRWHASNKQWAQSHSNKVLKSLETHVFPFIGNRDITTLNTPDLLIPVRAAEAKQIYEI
ASRLQQRISAVMRYAVQSGIIRYNPALDMAGALTTVKRQHRPALDLSRLPELLSRIGSYKGQPVTQLAVMLNLLVFIRSS
ELRYARWSEIDIDNAMWTIPAEREPLPGVKFSHRGSKMRTPHLVPLSKQAVAILTELQTWAGENGLIFTGAHDPRKPISE
NVMNASHTIKHGAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
c5216 NP_757064.1 prophage P4 integrase Not tested PAI II CFT073 Protein 8e-151 99
APECO1_3534 YP_854214.1 P4-like integrase Not tested PAI I APEC-O1 Protein 2e-150 98
ORF_1 AAZ04412.1 phage integrase Not tested PAI I APEC-O1 Protein 2e-150 98
int-phe AAL60261.1 Int-phe Not tested LEE Protein 1e-150 98
Z4313 NP_289539.1 pathogenicity island integrase Not tested OI-122 Protein 8e-150 98
int AAL51003.1 CP4-like integrase Not tested LEE Protein 1e-149 98
ECO103_3550 YP_003223418.1 integrase Not tested LEE Protein 2e-150 98
ECO26_5300 YP_003232178.1 integrase Not tested LEE Protein 2e-150 98
int-phe AAL57571.1 CP4-like integrase Not tested LEE Protein 1e-150 98
int AAL51028.1 CP4-like integrase Not tested LEE Protein 1e-150 98
int CAC81896.1 integrase Not tested LEE II Protein 2e-139 98
ECO111_3718 YP_003236059.1 putative integrase Not tested LEE Protein 2e-147 97
intP4 CAE85151.1 CP4 integrase protein Not tested PAI V 536 Protein 3e-149 97
int AAK16198.1 Int Not tested PAI-I AL862 Protein 2e-149 97
int ADD91747.1 P4 integrase Not tested PAI-I AL862 Protein 2e-149 97
int AAT48697.1 CP4-like integrase Not tested PAI I 4787 Protein 1e-149 97
c3556 NP_755431.1 prophage P4 integrase Not tested PAI I CFT073 Protein 1e-148 97
ECUMN_3322 YP_002414004.1 integrase Not tested Not named Protein 6e-147 97
S4822 NP_838459.1 P4-type integrase Not tested SHI-1 Protein 3e-149 96
SF2964 NP_708738.1 P4-type integrase Not tested SHI-1 Protein 3e-149 96
int AAK00456.1 Int Not tested SHI-1 Protein 5e-138 96
intB CAD42017.1 bacteriophage P4 integrase Not tested PAI II 536 Protein 3e-92 59
SESS1296_03598 AFO66301.1 bacteriophage integrase Not tested SESS LEE Protein 2e-91 57
SESS1635_03816 AFO66367.1 bacteriophage integrase Not tested SESS LEE Protein 2e-91 57
int CAB59974.1 integrase Not tested HPI Protein 1e-72 50
int NP_458759.1 bacteriophage integrase Not tested SPI-7 Protein 3e-78 50
int NP_807963.1 bacteriophage integrase Not tested SPI-7 Protein 3e-78 50
int2 NP_993013.1 integrase Not tested HPI Protein 1e-71 49
int CAA21384.1 - Not tested HPI Protein 1e-71 49
int CAA08754.1 integrase Not tested HPI Protein 1e-71 49
STY4821 NP_458899.1 integrase Not tested SPI-10 Protein 2e-81 49
unnamed AAD17660.1 unknown Not tested HPI Protein 4e-70 49
int YP_002346908.1 integrase Not tested HPI Protein 1e-71 49
y2393 NP_669700.1 prophage integrase Not tested HPI Protein 1e-71 49
APECO1_1051 YP_853069.1 phage integrase Not tested PAI IV APEC-O1 Protein 7e-46 46
unnamed ABR13507.1 phage integrase Not tested PAGI-6 Protein 4e-67 46
intB AAD37509.1 P4-like integrase Not tested PAI IV 536 Protein 2e-51 46
unnamed AFX83955.1 integrase Not tested SE-PAI Protein 2e-63 44
int CAC39282.1 integrase Not tested LPA Protein 1e-70 43
aec33 AAW51716.1 Int Not tested AGI-3 Protein 1e-70 43
ESA_03025 YP_001439090.1 hypothetical protein Not tested Not named Protein 5e-61 42
int AAD44730.1 Int Not tested SHI-2 Protein 4e-70 42
S4835 NP_839238.1 integrase Not tested SHI-2 Protein 1e-68 42
int AAD54663.1 Sai integrase Not tested SHI-2 Protein 1e-68 42
SF3698 NP_709437.1 integrase Not tested SHI-2 Protein 1e-68 42
int AAC31482.1 CP4-like integrase Not tested LEE Protein 8e-69 41
intL NP_290239.1 integrase for prophage 933L and the LEE pathogenicity island Not tested LEE Protein 1e-68 41
int ACU09430.1 integrase Not tested LEE Protein 8e-69 41
ECs4534 NP_312561.1 integrase Not tested LEE Protein 1e-68 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SSON53_18230 YP_005458150.1 P4-type integrase VFG1693 Protein 5e-149 97
SSON53_18230 YP_005458150.1 P4-type integrase VFG0626 Protein 1e-149 96
SSON53_18230 YP_005458150.1 P4-type integrase VFG1536 Protein 2e-92 59
SSON53_18230 YP_005458150.1 P4-type integrase VFG0598 Protein 5e-69 42
SSON53_18230 YP_005458150.1 P4-type integrase VFG0783 Protein 5e-69 41