Gene Information

Name : SSON53_16880 (SSON53_16880)
Accession : YP_005457882.1
Strain : Shigella sonnei 53G
Genome accession: NC_016822
Putative virulence/resistance : Virulence
Product : formate hydrogenlyase transcriptional activator FhlA
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 3151324 - 3152472 bp
Length : 1149 bp
Strand : +
Note : 'COG3604 Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains'

DNA sequence : 
ATGCTGGGCGTGCTGAAACTGGCGCAATGCGAAGAGAAAGTGTTTACCACTACCAATCTGAATTTGCTGCGCCAGATTGC
CGAACGTGTGGCAATCGCTGTCGATAACGCCCTCGCCTATCAGGAAATCCATCGTCTGAAAGAACGGCTGGTTGATGAAA
ACCTCGCCCTGACCGAGCAGCTCAACAATGTTGATAGTGAATTTGGCGAGATTATTGGCCGCAGCGAAGCCATGTACAGC
GTGCTTAAACAAGTTGAAATGGTGGCGCAAAGTGACAGTACCGTGCTGATCCTCGGTGAAACTGGCACGGGTAAAGAGCT
GATTGCCCGCGCGATCCATAATCTCAGTGGGCGTAATAATCGCCGCATGGTCAAAATGAACTGCGCGGCGATGCCTGCCG
GATTGCTGGAAAGCGATCTGTTTGGTCATGAGCGTGGGGCTTTTACCGGTGCCAGCGCCCAGCGCATTGGTCGTTTTGAA
CTGGCGGATAAAAGCTCTCTGTTCCTCGACGAAGTGGGCGATATGCCACTGGAGTTACAGCCGAAGTTGCTGCGTGTATT
GCAGGAACAGGAGTTTGAACGTCTCGGCAGCAACAAAATCATTCAGACGGACGTACGTTTAATTGCCGCGACTAACCGCG
ATCTGAAAAAAATGGTCGCCGACCGAGAGTTCCATAGCGATCTCTATTACCGCCTGAACGTATTCCCGATTCACCTGCCG
CCACTACGCGAGCGTCCGGAAGATATTCCGCTGCTGGCGAAAGCCTTTACCTTCAAAATTGCCCGTCGTCTGGGGCGCAA
TATCGACAGCATTCCTGCCGAGACGCTGCGCACCTTGAGCAACATGGAGTGGCCGGGTAACGTACGCGAACTGGAAAACG
TCATTGAGCGCGCGGTATTGCTAACACGCGGTAACGTGCTGCAGCTGTCATTGCCAGATATTGTTTTACCGGAACCTGAA
ACGCCGCCTGCCGCAACGGTTGTCGCCCAGGAGGGCGAAGATGAATATCAGTTGATTGTGCGCGTGCTGAAAGAAACCAA
CGGCGTGGTTGCCGGGCCTAAAGGCGCTGCGCAACGTCTGGGGCTGAAACGCACGACCCTGCTGTCACGGATGAAGCGGC
TGGGAATTGATAAATCGGCATTGATTTAA

Protein sequence : 
MLGVLKLAQCEEKVFTTTNLNLLRQIAERVAIAVDNALAYQEIHRLKERLVDENLALTEQLNNVDSEFGEIIGRSEAMYS
VLKQVEMVAQSDSTVLILGETGTGKELIARAIHNLSGRNNRRMVKMNCAAMPAGLLESDLFGHERGAFTGASAQRIGRFE
LADKSSLFLDEVGDMPLELQPKLLRVLQEQEFERLGSNKIIQTDVRLIAATNRDLKKMVADREFHSDLYYRLNVFPIHLP
PLRERPEDIPLLAKAFTFKIARRLGRNIDSIPAETLRTLSNMEWPGNVRELENVIERAVLLTRGNVLQLSLPDIVLPEPE
TPPAATVVAQEGEDEYQLIVRVLKETNGVVAGPKGAAQRLGLKRTTLLSRMKRLGIDKSALI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hrpS AAT96161.1 HrpS Virulence T-PAI Protein 6e-42 42
hrpS AAT96215.1 HrpS Virulence T-PAI Protein 6e-42 42
hrpS AAC35800.1 transcriptional regulator Virulence Hrp PAI Protein 2e-42 41
hrpR AAT96162.1 HrpR Virulence T-PAI Protein 1e-40 41
hrpR AAT96216.1 HrpR Virulence T-PAI Protein 1e-40 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SSON53_16880 YP_005457882.1 formate hydrogenlyase transcriptional activator FhlA BAC0467 Protein 1e-64 44
SSON53_16880 YP_005457882.1 formate hydrogenlyase transcriptional activator FhlA BAC0089 Protein 3e-61 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SSON53_16880 YP_005457882.1 formate hydrogenlyase transcriptional activator FhlA VFG1248 Protein 9e-59 44