Gene Information

Name : lp12_0849 (lp12_0849)
Accession : YP_005185218.1
Strain : Legionella pneumophila ATCC 43290
Genome accession: NC_016811
Putative virulence/resistance : Virulence
Product : UDP-glucose/GDP-mannose dehydrogenase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 924822 - 926108 bp
Length : 1287 bp
Strand : +
Note : -

DNA sequence : 
ATGTGCTTAAAACGAAGAATAGTAATGATGGGTCTGGGATATGTCGGTTTAACCCTTGCTGTCGCCTTGGGAAAAATTAC
AAGAGTGATAGCATATGATAAGAATTCATCACGGATTTCCGAACTTAAAAATGGCCAGGATAGGAATTTGGAAGTCGAAG
ATGATGCTTTAGCTGTAAGCGATCTTCTATTAACATCCGACCCGAAGGAACTGGAAAATGGTGATTTTTATATCATAGCT
GTTCCAACTCCATTGAATAAAAACAGGCAGGTTGATTTCTCAATGTTGTTTGAGGCAACAAAATTGGTTGGAAAATGTCT
TAAAAAGGGGGATATTGTTGTTTACGAATCATCTGTTTATCCAGGAGCTACAGAAGAGCAATGTATCCCGCTACTTGAAA
AAAGCTCCAAATTAATTTGCGGCGAGAGTTTTTCTGTAGGCTACTCTCCGGAACGTATTAATCCCTCAGATCAAGAGCAT
GTTCTTCAAAACATAGTGAAAATTGTTTCTGCCACTGATGGAGATACTTTGAATATTATCTCGGAAGTGTATAACAGCAT
AATTAACGCAGGAGTTTTTCCAGTTTCCTCCATACGCGTCGCTGAGGCGGCAAAGGTGATTGAAAATGCGCAAAGGGACA
TCAACATAGGTTTTATAAATGATATTGCTGTTATGTTGCATCATCTTGGCATTGATACAGCGGAAGTGATCCAGGCAATG
AAAACCAAATGGAATTATATCCCTTTTCAACCTGGATTAGTGGGTGGTCACTGTATCGGTATTAATTCATATTACTTGAT
GCACAAAGCGGAAGAGATTGGATATTACTCAAACCTTATTATGGCGGGAAGGCAGATTAATGAATCCATTGCAAAATTTA
TCGCAGAACAAACCATAAAACAGTTAATTCGCCAGGGAAGTCCTGTAAAAAGGGCGCGAATTGCAATTTTAGGATTAACC
TATAAGGAAAATTGTTCTGATCTCCGCGACACCCGAGTAATTGATATTATTAGAGAATTACAATCGTATGATACCGAGCT
ATTTATTCATGATCCTATCGCTGACGCTGTAGCCGCAAAGAAACATTACGGTATCGAACTTCAATCCTGGGAAAATCTTA
ATGATCTGGATGCCATGATTTTTACTGTGTCACATCAATACTATTTGACTATGGACAGACATGAAATAAAAAATAAATTA
AATTGGCACGGCCTTATCATGGATGTAAAAGAAATTTTTAATTATGAAGAGTTCAAGGATACTGGAATTTTACTCTGGAG
GCTATGA

Protein sequence : 
MCLKRRIVMMGLGYVGLTLAVALGKITRVIAYDKNSSRISELKNGQDRNLEVEDDALAVSDLLLTSDPKELENGDFYIIA
VPTPLNKNRQVDFSMLFEATKLVGKCLKKGDIVVYESSVYPGATEEQCIPLLEKSSKLICGESFSVGYSPERINPSDQEH
VLQNIVKIVSATDGDTLNIISEVYNSIINAGVFPVSSIRVAEAAKVIENAQRDINIGFINDIAVMLHHLGIDTAEVIQAM
KTKWNYIPFQPGLVGGHCIGINSYYLMHKAEEIGYYSNLIMAGRQINESIAKFIAEQTIKQLIRQGSPVKRARIAILGLT
YKENCSDLRDTRVIDIIRELQSYDTELFIHDPIADAVAAKKHYGIELQSWENLNDLDAMIFTVSHQYYLTMDRHEIKNKL
NWHGLIMDVKEIFNYEEFKDTGILLWRL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cap1L AAA64651.1 type 1 capsule synthesis gene Virulence SCCcap1 Protein 3e-102 49
tviB NP_458740.1 Vi polysaccharide biosynthesis protein, UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 5e-90 48
tviB NP_807945.1 VI polysaccharide biosynthesis UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 5e-90 48

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lp12_0849 YP_005185218.1 UDP-glucose/GDP-mannose dehydrogenase VFG0431 Protein 2e-90 48