Gene Information

Name : lp12_2070 (lp12_2070)
Accession : YP_005186418.1
Strain : Legionella pneumophila ATCC 43290
Genome accession: NC_016811
Putative virulence/resistance : Resistance
Product : cadmium translocating P-type ATPase CadA
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2287849 - 2290029 bp
Length : 2181 bp
Strand : -
Note : -

DNA sequence :
ATTCATTACAAAGGTTATATTTTACGGACAATGCGGAAAAACCAAATGACAGTACCTTTAAATGAAACCAAATTTTTTGT
TGCAGGACTTGATTGTCCAGCGGAAGAGCAACTAATCAGAAAGCAGTTACAGGATATTCCTGAAGTGGAGCAGTTGGATT
TTAATTTTATTGCTGAAGAAGTTACTATTCATCACCGGTTGGCTTCAAGTGAAGAATTGCAAAAACGCATTGAGGCGTTG
GGAATGAGTGTTCGAACGCTGGAAAGCACTTTACCTATACCACAAAGAAAACAATTATCGTTGGATTTTTCCTGGAAAAT
TATTGGACTAGCAGGTTTTCTTGCCCTATTTTCTGAGCTGGCAGCTTATTTTTTGGCTACGGAACAATCCATTTGGACTA
TTCTTCCAGCTTTGTTGGCTATTGGTCTTAGTGGGCCTTCTACCTTTAAAAAAGGGTGGCTTGCCTTAGGGACTAAAACA
ATGAATATCAATAGCTTGATGTTCATTGCGATAGCAGGGGCTGTTCTTATTGGAGAGTGGCCTGAAGCGGCAATGGTGAC
TGTTTTATTTGCATTGGCCGAACGTATCGAGCGCTACTCCTTAGATAAAGCACGTCTTGCGATTCGAAGCTTAATGCAAA
TTGCCCCTGAGGTGGCTTCAGTGAAACAGGACGATGGTCAATGGCAAACCTTGGCCATTGAAAAAGTGGTGCCTGGTGCT
ATTTTTAGAGTAAAACCTGGAGAGCGTATTCCCCTGGATGGCGTGGTTATTTCAGGTCAGAGCACGGTCAATCAAGCGCC
GATTACTGGTGAATCAATGCCAATAACAAAAAAAGTGGGTGATTTGGTTTTTGCAGGAACATTAAATGAGCACGGCGCGT
TTGAAGTGCAGGTCAGTAAAGTGTCAGGCGATACATTGCTTGCTAAAATTGGTAAAGCGATAGAGCAAGCGCAAGCGGAT
CGAGCTCCAACACAACGATTTGTTGATCAGTTTTCTAAATATTATACTCCAATTATGGTATTGATGGCTTTTTTTGTTGC
ATTAATTCCACCTTTAGCATTTGGTTATCCTTTTTATGATTCTCTTTATAAGTCACTGACTTTATTAGTTATTGCTTGCC
CTTGCGCTTTAGTGATTTCAACACCCGTGACTGTTGTAAGTGGCCTTGCAGCGGCAGCAAAACAAGGGCTTCTTATTAAA
GGAGGAAGCTACTTAGAGGTTGGTCATCGACTGAGGTTAATTGCTTTAGATAAGACAGGTACTTTAACGGAAGGAAAGCC
AGTTGTAACTGACTTCATAGCTTGGGATGAAAATCGAACTAAGGAGAGTTTGTTATTGTTAGCTGCAAGCCTTGATAGTC
ACTCAGAGCATCCAGTCGCTAATGCCTTAGTACAGTACTGGCAACAGGAACAACCTCAAAACGCTTTACTTGAAATTGAG
CAATTTTCAGCACTTCCTGGACGAGGAGTAAAGGGATTAGTGGGTCAAGAACTCTATTTTGTAGGCAATCATCAGTTAGC
TGAAGACAATCAGGTATGCAATCATTTTGTCGAACAAGAGCTGAAGCGCTTGGAGGAAGAAGGTAAAACGACCGTAATAT
TAAGTAATGCTACGACTGTTTTGGCTATTTTTGCAGTAGCTGATACTTTACGTGTTACAAGCCAACAGGCGATTGCACAA
CTACATGAACGGGGTATAAAAACCGCGATGTTAACGGGAGACAATGCGGTAACGGCTCAGGCTATTGCTAAAAAAGTAGG
TATTGATGAAGTAAATGCAAATATATTACCTGCGGAAAAACTGCAAGCGATTAATGGTCTTTTAGATCACTATAATAGCG
TTGGGATGGTAGGAGATGGAATTAATGATGCCCCTGCATTGGCAAAAGCTACCGTGAGTTTTGCGATGGGGAAAGGAACA
GATACTGCCTTAGAAACTGCAGACGTTGCCCTAATGAACGACAATCTAGCAAGACTCCCCTTTTATATTGATTTAAGTCG
TAAGACAGCACGTACTCTTTATCAAAACATCAGTTTATCTATTGCGATTAAAGGCATTTTCTTTATTTTGGCTCTTGTAG
GGTATGCAACGTTATGGATGGCAGTTTTTGCAGACATGGGAGCGAGTTTAATCGTAGTGGCTAATGGATTGCGATTGTTG
TATATGTCCCCAGATGATTAA

Protein sequence :
MHYKGYILRTMRKNQMTVPLNETKFFVAGLDCPAEEQLIRKQLQDIPEVEQLDFNFIAEEVTIHHRLASSEELQKRIEAL
GMSVRTLESTLPIPQRKQLSLDFSWKIIGLAGFLALFSELAAYFLATEQSIWTILPALLAIGLSGPSTFKKGWLALGTKT
MNINSLMFIAIAGAVLIGEWPEAAMVTVLFALAERIERYSLDKARLAIRSLMQIAPEVASVKQDDGQWQTLAIEKVVPGA
IFRVKPGERIPLDGVVISGQSTVNQAPITGESMPITKKVGDLVFAGTLNEHGAFEVQVSKVSGDTLLAKIGKAIEQAQAD
RAPTQRFVDQFSKYYTPIMVLMAFFVALIPPLAFGYPFYDSLYKSLTLLVIACPCALVISTPVTVVSGLAAAAKQGLLIK
GGSYLEVGHRLRLIALDKTGTLTEGKPVVTDFIAWDENRTKESLLLLAASLDSHSEHPVANALVQYWQQEQPQNALLEIE
QFSALPGRGVKGLVGQELYFVGNHQLAEDNQVCNHFVEQELKRLEEEGKTTVILSNATTVLAIFAVADTLRVTSQQAIAQ
LHERGIKTAMLTGDNAVTAQAIAKKVGIDEVNANILPAEKLQAINGLLDHYNSVGMVGDGINDAPALAKATVSFAMGKGT
DTALETADVALMNDNLARLPFYIDLSRKTARTLYQNISLSIAIKGIFFILALVGYATLWMAVFADMGASLIVVANGLRLL
YMSPDD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ORF C97 AAN62190.1 putative metal-transporting P-type ATPase Not tested PAGI-2(C) Protein 7e-159 52
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 1e-123 43
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 3e-122 41
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 3e-122 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lp12_2070 YP_005186418.1 cadmium translocating P-type ATPase CadA BAC0298 Protein 4e-158 51