Gene Information

Name : lp12_2067 (lp12_2067)
Accession : YP_005186415.1
Strain : Legionella pneumophila ATCC 43290
Genome accession: NC_016811
Putative virulence/resistance : Resistance
Product : cadmium efflux ATPase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2284937 - 2286844 bp
Length : 1908 bp
Strand : -
Note : -

DNA sequence :
ATGGGCTGCTCGACATGCTCTTCACATAAGGAGCCAATGCCAAAGTTGTGGCATAATCCCAAAGTCATTACAGCAACTAT
AGCTGGTTTATTATTAACTATTGGTTTTGTAGGCTCATATTTGGCATTACCAATGATTATCGCTAATGGGTTTTACATAG
GCGCAGTATTAATTGGCGGATATTATTTCGCACGCGAAGCAATAGACGAATTTATCAAAGAATATGAAATCGGTATTGAA
TTCTTGATGTCTCTTGCAGCCATTGTTGCAGGTATCATGGGGCAATGGGCGGAAGCAGCAACATTGGTATTTTTGTATTC
TATTTCTGAAGCTGCGGAAGGTTATTCCGGTGAAAGAGCGCGGCATGCTATCCGAGCATTGATGGATCTTGCCCCAAAAA
CAGCATTAATCCGGCGAAATAATACTGAATTTCGAATACCCATAGAAGAAATTCATATTGGAGATGAATTCATTGTTCTT
CCTGGTGAAAGTCTTGCTACAGATGGAGAAGTCATTTCAGGACATTCTAGTGTTAATCAAGCACCTATTACGGGTGAGTC
AATTCCAGTAGAAAAAACTATAGGGAGTAAAGTTTTTTCTGCAACTATAAACGGTGAAGGAACTCTTACTGTTCGTGCAA
CCAAAAAATTTGCTGATAATACATTATCTCGTATCATATTTCTTGTTGAAAAAGCACAAGACAAAAAGGGGCGTAGTCAA
CGTTTTATAGAACGTTTTGGCAACCTATATAGTCCATTTATCCTTTTGGCGGGAATACTCATAGCTACTTTACCACCTCT
ATTTGGGCAACCTTGGCAAGAGTGGGTGATTCGTGCCACAGTATTTATTGTTGCTGCAGCGCCATGTGCCCTAGTGATTT
CTATACCCATTACACTTGTAGCTGCTCTTGGCACAGCAAGTCGAAATGGAATATTACTAAAAGGTGGATTATATTTGGAG
CAACTAGTGAAGATAAAAGTTATTGCACTAGATAAAACAGGAACATTAACACAAGGTAAACCGAAGGTTACTGATATCAT
TCCATTGAATAACCATACTCGGAACCAAATTTTAAATGCAGCAGCAACTCTTGAATCGCGCTCCCAGCATCCCATGGCCC
AAGCCATTTTGCAACAAGCCAATGAAGAAAATATTCAATATAATCCTGTTGAACAGTTTAAGTCATTAACTGGTTCAGGT
GTACTTGGTTTTATCAATGGGAAAAAATTCTACATAGGCAATCCAAAATTATTTATTGATATGGGCCTATTGATAGAAAC
ATTAACGCAGGAAATAAATAAATTACAGGCCTCTGGAAAGACAGTAGTATTATTAGGAACTGATAAGGAAATCCTCGGTT
TAATTGCAATTGCTGATCCTCTAAGACCAACAGCAAGGCAGATGGTGTCTAACTTAAAATTGATGGGTATTGAACGTGTG
GTTATGCTCACAGGAGATAATTTGATAACTGCCTCTTCAATTGGTGAACAGGCGGGTGTTGATGAAGTATTTTCTGATTT
ATCACCAGAAGATAAGACACGAAAAATTGAAGAGTTAGAAAGACGTTATGGTAAGGTAATGATGGTTGGTGATGGAGTAA
ATGATGCTCCAGCACTCGCAGCAGCTCATGTAGGAGTTGCTATGGGTGCTGTCGGAACCGATGTTGCATTAGAAACTGCG
GATGTAGCCTTAATGGGTGATAATTTATTAAAATTACCTTATCTTATCGCATTTAGTCGTCGAACTTGGAATATAATTTT
ACAAAATTTGGGACTTTCTATAATTGTAATTAGCTCTCTTGTTGTCGGGGCAGTAACAGGTTATTTTACGTTGCCGATAG
CAGTTTTAGCTCATGAAATCAGTGAGCTTATTGTTATTGCAAGTGGTCTTCGTATGTTAAAATCTTAA

Protein sequence :
MGCSTCSSHKEPMPKLWHNPKVITATIAGLLLTIGFVGSYLALPMIIANGFYIGAVLIGGYYFAREAIDEFIKEYEIGIE
FLMSLAAIVAGIMGQWAEAATLVFLYSISEAAEGYSGERARHAIRALMDLAPKTALIRRNNTEFRIPIEEIHIGDEFIVL
PGESLATDGEVISGHSSVNQAPITGESIPVEKTIGSKVFSATINGEGTLTVRATKKFADNTLSRIIFLVEKAQDKKGRSQ
RFIERFGNLYSPFILLAGILIATLPPLFGQPWQEWVIRATVFIVAAAPCALVISIPITLVAALGTASRNGILLKGGLYLE
QLVKIKVIALDKTGTLTQGKPKVTDIIPLNNHTRNQILNAAATLESRSQHPMAQAILQQANEENIQYNPVEQFKSLTGSG
VLGFINGKKFYIGNPKLFIDMGLLIETLTQEINKLQASGKTVVLLGTDKEILGLIAIADPLRPTARQMVSNLKLMGIERV
VMLTGDNLITASSIGEQAGVDEVFSDLSPEDKTRKIEELERRYGKVMMVGDGVNDAPALAAAHVGVAMGAVGTDVALETA
DVALMGDNLLKLPYLIAFSRRTWNIILQNLGLSIIVISSLVVGAVTGYFTLPIAVLAHEISELIVIASGLRMLKS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 1e-121 45
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 5e-120 45
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 5e-120 45

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lp12_2067 YP_005186415.1 cadmium efflux ATPase BAC0298 Protein 9e-94 44
lp12_2067 YP_005186415.1 cadmium efflux ATPase BAC0092 Protein 1e-100 43
lp12_2067 YP_005186415.1 cadmium efflux ATPase BAC0100 Protein 1e-87 43
lp12_2067 YP_005186415.1 cadmium efflux ATPase BAC0124 Protein 1e-86 41