Gene Information

Name : lp12_1154 (lp12_1154)
Accession : YP_005185521.1
Strain : Legionella pneumophila ATCC 43290
Genome accession: NC_016811
Putative virulence/resistance : Virulence
Product : two component response regulator PilR
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1259426 - 1260754 bp
Length : 1329 bp
Strand : +
Note : Protein fate / hydrolases / secretion, Signal transduction / other regulatory functions

DNA sequence : 
ATGATCAAAAGTAAAGTGCTTGTTATAGATGACGAACCAGACATTAGAGAGTTATTAACTCTTACTTTATCACGCATGGG
TTTAATTTGTGATGCGGTGTCTGATTTTAAGCAGGGCATAGAACATATAAAACAAAATTATTATTCTTTGGTTTTAACCG
ATATGCGTTTGCCTGACGGAGATGGTATAGAAATTGTTAAATTCATTCAGAAATACAAACCACAGTTGCCAGTCGCTGTC
ATTACTGCTTATGGAAATGTAGAAGGTGCGGTCAATACTTTAAAGGCTGGTGCATTTGATTATGTATCCAAGCCTGTTGA
CTTAAAGATGCTCAGAGAACTCGTTAAGACGGCATTATCCATGCAAAATCCGTCTACCGAGAGTCCTGATGAAGGTCTAT
TGGTTGGTGAGAGCCTGATAATGCAACAACTGCGTGAGAGCATTCATAAATTAGCTCGTAGTCAGGCACCGGTTTTCATT
CAAGGTGATTCGGGTGTTGGGAAAGAACTTGTTGCTCAGCTGATCCATGCTAATGGTCCCAGAAAAGATAAGCCATTTAT
TCCTGTAAATTGTGGTGCCATACCTGGTGAGTTGATGGAGTCAGAGTTTTTTGGCCATAAAAAAGGAAGTTTTACAGGAG
CGATTTCGGATAAAACAGGATTATTTGTTGCAGCTCATGGCGGCACTTTGTTTCTTGATGAAATCGCCGAACTTCCTCTC
GCCATGCAGGTTAAATTACTACGCGCAATTCAGGAGAAGGCAATTAAACCAATAGGTGAGTTATATGAAATTCCGGTCGA
TGTTCGCATTCTAAGTGCGAGTCATAAAAATTTGATTGAGGAAATCAATGCAGGGAGGTTTCGTCAAGATTTGTATTATC
GAATTAATGTGATTGAGCTGCGTGTTCCAACTTTAATGGAAAGGCTTTCTGATATCCCTTGCCTGACAGAGGCGATATTA
AAAAAATTATCTAAAAATCAAAACAGAAATTTGGTTAAAATAAATCCCTCTTGTTTTGAAATATTGAGCCGTTATCATTT
CCCGGGAAATGTCAGAGAGTTGGAAAATATCCTTGAGCGTGCCATGGCTATGTGTGAAGGAGAGGTCATAGAGCCAAGCG
ATTTACATTTGCCCAGAACAACAATAACCCCAGCTGTTGCCGTACCCTCCACGTCAACTAACTTAAATGGTTACCTTCAG
GATCAGGAAAAAGAGTTAATTCTTGATGCGCTTGAGAAAACAAAATGGAACAGAACCGCTGCGGCACAACTACTGGGGGT
CAGCTTCCGAACTCTCCGTTATCGATTAAAAAAACTGGGACTTGATTAG

Protein sequence : 
MIKSKVLVIDDEPDIRELLTLTLSRMGLICDAVSDFKQGIEHIKQNYYSLVLTDMRLPDGDGIEIVKFIQKYKPQLPVAV
ITAYGNVEGAVNTLKAGAFDYVSKPVDLKMLRELVKTALSMQNPSTESPDEGLLVGESLIMQQLRESIHKLARSQAPVFI
QGDSGVGKELVAQLIHANGPRKDKPFIPVNCGAIPGELMESEFFGHKKGSFTGAISDKTGLFVAAHGGTLFLDEIAELPL
AMQVKLLRAIQEKAIKPIGELYEIPVDVRILSASHKNLIEEINAGRFRQDLYYRINVIELRVPTLMERLSDIPCLTEAIL
KKLSKNQNRNLVKINPSCFEILSRYHFPGNVRELENILERAMAMCEGEVIEPSDLHLPRTTITPAVAVPSTSTNLNGYLQ
DQEKELILDALEKTKWNRTAAAQLLGVSFRTLRYRLKKLGLD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00300 YP_008207765.1 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Not tested AbaR25 Protein 4e-98 49
BJAB0868_00304 YP_008211630.1 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Not tested AbaR26 Protein 4e-98 49

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lp12_1154 YP_005185521.1 two component response regulator PilR BAC0467 Protein 5e-79 44
lp12_1154 YP_005185521.1 two component response regulator PilR BAC0089 Protein 2e-71 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lp12_1154 YP_005185521.1 two component response regulator PilR VFG1214 Protein 4e-132 60