Gene Information

Name : hcsA' (HIB_11800)
Accession : YP_005179206.1
Strain : Haemophilus influenzae 10810
Genome accession: NC_016809
Putative virulence/resistance : Virulence
Product : capsule biosynthesis protein HcsA
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1210312 - 1212354 bp
Length : 2043 bp
Strand : -
Note : -

DNA sequence :
ATGCCAACTGCACTGATTTTCTCGCACGGAATCAAAAAAATTCCGCATTTAGCCTCATTTTTTCCTAATGAAGAATTGGC
TTTCGCACGCATTTTTTCTGTGTCGAAGGCTGATTCTGTATTGGGTTGGGGGTTACGTCCTTCCACGAAAAAATCACGTG
CATATGCACAAAAGTATAACTTACCGTTTATCGCCTTAGAAGACGGTTTTTTACGTTCTCTTGGTCTGGGGGTTGATGGT
TATCCGCCGCTTTCTATGGTTGTGGATAAATTAGGTATTTATTACGACACGACTCGTCCCTCAACATTGGAACAGCTTAT
TCAGGCAGGTGAATGTGATGAGGTTTTAGCGGAAAAAGCTCGGTCACAAATTGTGACGCATCAGCTTTCAAAATATAACC
AAACATTGGTGGATTATGAGAAAGAAGGTGACGAACCGTTAGTACTTGTCATTGACCAAACTTTTGGTGATATGGCAGTG
AAATATGGTCAAGCCGATGCCGAGCATTTTGCGCAAATGTTGCAAGCTGCCATTTCAGAAAATCCAAACGCTAAAATTTT
AGTGAAAACCCATCCTGATGTATTAAGTGGTAAAAAACAGGGCTATTTTTCGCCAAATGAAAATTATCCAAGCAACGTGC
ATTTTTTTAGTAACCCCGTCAATCCGATTTCACTAATTAAAGCCGTAGAGAAAGTTTATTGTGTTACCTCTCAAATGGGG
TTTGAAGCATTATTAATGGGTAAACCGGTGGTGACTTTTGGCGTACCATGGTTTGCTGGCTGGGGTGTGACGGATGATCG
TCATCCGAATGCTAAAGCGCTAACGCAAAGTGAGCGCCGTAAAGTGCGGTCAGTTTTACAACTGTTTTATGCAGCATACT
TTCAATATACCCGTTATTTGAATCCGAATACCGGCAAATCGGGAACGATTTTTGATGTCATTAACCACATCATTCACACC
AAAGCACTTAACTTGCGATTACAAGGCAATCTCTATTGCGTTGGAATATCCTTGTGGAAACGTGCGGTTATTAAACCGTT
TTTCCGTTTACCAAGCTGCAAGCTACATTTTGTTACAGATGTGAGTAAACTCAATGGTAAAACATTCACAAAAAATGACC
GCTTGTTACTATGGGGAACGGGTAAAGAAGCCGCGCTAAATTATGCTAAAGCGCATAATATTAACGTGCTCAGAATGGAA
GATGGGTTTATTCGTTCAGTTGGGCTTGGCTCAAACTTGGTTGCGCCACTTTCTTTGGTGTGTGACGATTTAGGTATCTA
TTTCAATGCAGAAAGCCCTTCTCGCTTAGAAGAGATTTTGCAGCATCAACAATTTACCGAAGCAGATTTAATCGAAGCCA
AGCAGCTACAACATGCGTTAGTATCGCAACATATCGGTAAATATAATGTCGGCGAAGGTACATTTTCTCTGCCTAATACA
GACAAAAAGAAAATTTTAGTGGTCGGGCAGGTCGAAGACGATGCCTCTATTCGAACCGGCTCACCGAATATTCGTACTAA
TCTAGATTTATTAAAAACAGTGCGCGCAGCAAACCCAGAAGCTTATATCGTTTATAAGCCACACTCGGATGTTGTGAGTG
GTAACCGCATTGGTCATATTGCAGAATCGCAAGCGGTCAAATTAGCGGATCAAATTGCAAAAACAGAAAACGTGCTTGAC
TGCATCAATGCCGTGGATGAACTACACACCATGACATCTCTTGCAGGTTTTGAAGCCTTGCTAAGAAACAAAACGGTGCA
TTGTTATGGTTTGCCATTTTATAGCCACTGGGGATTGACCGTTGATCACTGCTCTTTTAACCGCCGCAATCGAAAACTTT
CATTGTTAGAACTTATTGCTGGCACATTGGTCTATTATCCACAATATGTTAATCCGAATACGGGTGAGCTAACCAATGCT
CAAACAACGATTGAAATTTTAAAAGCACAGCGTTTAGCGCTTAATCACAGTGGCATTCATCGCCATTGGTTGGCAAAACA
ATATGGCAAATTACAGCATTTAGTGCGCACATTGCGTACTTAA

Protein sequence :
MPTALIFSHGIKKIPHLASFFPNEELAFARIFSVSKADSVLGWGLRPSTKKSRAYAQKYNLPFIALEDGFLRSLGLGVDG
YPPLSMVVDKLGIYYDTTRPSTLEQLIQAGECDEVLAEKARSQIVTHQLSKYNQTLVDYEKEGDEPLVLVIDQTFGDMAV
KYGQADAEHFAQMLQAAISENPNAKILVKTHPDVLSGKKQGYFSPNENYPSNVHFFSNPVNPISLIKAVEKVYCVTSQMG
FEALLMGKPVVTFGVPWFAGWGVTDDRHPNAKALTQSERRKVRSVLQLFYAAYFQYTRYLNPNTGKSGTIFDVINHIIHT
KALNLRLQGNLYCVGISLWKRAVIKPFFRLPSCKLHFVTDVSKLNGKTFTKNDRLLLWGTGKEAALNYAKAHNINVLRME
DGFIRSVGLGSNLVAPLSLVCDDLGIYFNAESPSRLEEILQHQQFTEADLIEAKQLQHALVSQHIGKYNVGEGTFSLPNT
DKKKILVVGQVEDDASIRTGSPNIRTNLDLLKTVRAANPEAYIVYKPHSDVVSGNRIGHIAESQAVKLADQIAKTENVLD
CINAVDELHTMTSLAGFEALLRNKTVHCYGLPFYSHWGLTVDHCSFNRRNRKLSLLELIAGTLVYYPQYVNPNTGELTNA
QTTIEILKAQRLALNHSGIHRHWLAKQYGKLQHLVRTLRT

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lipA NP_273145.1 capsule polysaccharide modification protein Not tested IHT-A Protein 0.0 58
kpsC AAZ04470.1 capsule polysaccharide export protein Virulence PAI I APEC-O1 Protein 2e-132 48
kpsC YP_854335.1 capsule polysaccharide export protein KpsC Not tested PAI I APEC-O1 Protein 3e-132 48

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
hcsA' YP_005179206.1 capsule biosynthesis protein HcsA VFG0692 Protein 0.0 97
hcsA' YP_005179206.1 capsule biosynthesis protein HcsA VFG0704 Protein 0.0 97
hcsA' YP_005179206.1 capsule biosynthesis protein HcsA VFG0259 Protein 0.0 58