Gene Information

Name : floR (Pmu_02820)
Accession : YP_005176183.1
Strain : Pasteurella multocida 36950
Genome accession: NC_016808
Putative virulence/resistance : Resistance
Product : florfenicol / chloramphenicol efflux protein
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 286824 - 288038 bp
Length : 1215 bp
Strand : +
Note : -

DNA sequence :
ATGACCACCACACGCCCCGCGTGGGCCTATACGCTGCCGGCAGCACTGCTGCTGATGGCTCCTTTCGACATCCTCGCTTC
ACTGGCGATGGATATTTATCTCCCTGTCGTTCCAGCGATGCCCGGCATCCTGAACACGACGCCCGCTATGATCCAACTCA
CGTTGAGCCTCTATATGGTGATGCTCGGCGTGGGCCAGGTGATTTTTGGTCCGCTCTCAGACAGAATCGGGCGACGGCCA
ATTCTACTTGCGGGCGCAACGGCTTTCGTCATTGCGTCTCTGGGAGCAGCTTGGTCTTCAACTGCACCGGCCTTTGTCGC
TTTCCGTCTACTTCAAGCAGTGGGCGCGTCGGCCATGCTGGTGGCGACGTTCGCGACGGTTCGCGACGTTTATGCCAACC
GTCCTGAGGGTGTCGTCATCTACGGCCTTTTCAGTTCGGTGCTGGCGTTCGTGCCTGCGCTCGGCCCTATCGCCGGAGCA
TTGATCGGCGAGTTCTTGGGATGGCAGGCGATATTCATTACTTTGGCTATACTGGCGATGCTCGCACTCCTAAATGCGGG
TTTCAGGTGGCACGAAACCCGCCCTCTGGATCAAGTCAAGACGCGCCGATCTGTCTTGCCGATCTTCGCGAGTCCGGCTT
TTTGGGTTTACACTGTCGGCTTTAGCGCCGGTATGGGCACCTTCTTCGTCTTCTTCTCGACGGCTCCCCGTGTGCTCATA
GGCCAAGCGGAATATTCCGAGATCGGATTCAGCTTTGCCTTCGCCACTGTCGCGCTTGTAATGATCGTGACAACCCGTTT
CGCGAAGTCCTTTGTCGCCAGATGGGGCATCGCAGGATGCGTGGCGCGTGGGATGGCGTTGCTTGTTTGCGGAGCGGTCC
TGTTGGGGATCGGCGAACTTTACGGCTCGCCGTCATTCCTCACCTTCATCCTACCGATGTGGGTTGTCGCGGTCGGTATT
GTCTTCACGGTGTCCGTTACCGCGAACGGCGCTTTGGCAGAGTTCGACGACATCGCGGGATCAGCGGTCGCGTTCTACTT
CTGCGTTCAAAGCCTGATAGTCAGCATTGTCGGGACATTGGCGGTGGCACTTTTAAACAGTGACACAGCGTGGCCCGTGA
TCTGTTACGCCACGGCGATGGCGGTACTGGTTTCGTTGGGGCTGGTGCTCCTTCGGCTCCGTGGGGCTGCCACCGAGAAG
TCGCCAGTCGTCTAA

Protein sequence :
MTTTRPAWAYTLPAALLLMAPFDILASLAMDIYLPVVPAMPGILNTTPAMIQLTLSLYMVMLGVGQVIFGPLSDRIGRRP
ILLAGATAFVIASLGAAWSSTAPAFVAFRLLQAVGASAMLVATFATVRDVYANRPEGVVIYGLFSSVLAFVPALGPIAGA
LIGEFLGWQAIFITLAILAMLALLNAGFRWHETRPLDQVKTRRSVLPIFASPAFWVYTVGFSAGMGTFFVFFSTAPRVLI
GQAEYSEIGFSFAFATVALVMIVTTRFAKSFVARWGIAGCVARGMALLVCGAVLLGIGELYGSPSFLTFILPMWVVAVGI
VFTVSVTANGALAEFDDIAGSAVAFYFCVQSLIVSIVGTLAVALLNSDTAWPVICYATAMAVLVSLGLVLLRLRGAATEK
SPVV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
floR YP_005176183.1 florfenicol / chloramphenicol efflux protein Not tested ICEPmu1 Protein 2e-161 100
flo AAK02049.1 chloramphenicol and florfenicol resistance protein Not tested SGI1 Protein 2e-161 99
floRc AGK06972.1 chloramphenicol and florfenicol resistance protein Not tested SGI1 Protein 2e-161 99
floRc AGK07102.1 chloramphenicol and florfenicol resistance protein Not tested SGI1 Protein 2e-161 99
cmlA9 ABZ01840.1 CmlA9 chloramphenicol efflux protein Not tested SGI2 Protein 6e-149 92
cmlA CAJ77032.1 chloramphenicol and florfenicol resistance protein Not tested AbaR1 Protein 6e-149 92
cmlA5 CAJ77046.1 Chloramphenicol resistance protein Not tested AbaR1 Protein 1e-81 51
cml(A)5 ACY75522.1 CmLA(5) Not tested Tn6060 Protein 7e-82 50

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
floR YP_005176183.1 florfenicol / chloramphenicol efflux protein DQ522237.1.gene4.p01 Protein 5e-82 50
floR YP_005176183.1 florfenicol / chloramphenicol efflux protein NC_010410.6003586.p0 Protein 5e-82 50
floR YP_005176183.1 florfenicol / chloramphenicol efflux protein DQ984668.gene.p01 Protein 5e-82 50
floR YP_005176183.1 florfenicol / chloramphenicol efflux protein AF156486.gene.p01 Protein 1e-80 49
floR YP_005176183.1 florfenicol / chloramphenicol efflux protein AF294653.1.gene4.p01 Protein 1e-81 49