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Name : glpK (BCGMEX_3755c) Accession : YP_005173206.1 Strain : Mycobacterium bovis Mexico Genome accession: NC_016804 Putative virulence/resistance : Unknown Product : glycerol kinase Function : - COG functional category : - COG ID : - EC number : 2.7.1.30 Position : 4090680 - 4092236 bp Length : 1557 bp Strand : - Note : In Mycobacterium tuberculosis, Mycobacterium bovis BCG Pasteur, BCG Tokyo and BCG Mexico, glpK exists as a single gene. In Mycobacterium bovis, a frameshift due to a single base insertion, splits glpK into 2 parts, glpKa and glpKb and removes activity. Di DNA sequence : GTGTCCGACGCCATCCTAGGAGAGCAATTGGCCGAGTCCTCGGATTTCATAGCCGCCATCGACCAGGGCACCACCAGCAC CCGCTGCATGATCTTCGATCACCACGGTGCCGAGGTGGCCCGCCACCAGCTCGAGCACGAGCAGATCCTGCCCCGGGCCG GCTGGGTGGAGCACAACCCGGTCGAGATCTGGGAGCGCACCGCGTCGGTGTTGATCTCGGTGCTCAACGCCACCAACCTA TCGCCGAAAGATATTGCCGCGTTGGGGATTACCAACCAACGTGAGACGACGCTGGTATGGAATCGGCACACCGGACGGCC CTACTACAACGCGATTGTATGGCAGGATACCCGCACCGACCGCATCGCGTCGGCGCTGGATCGAGACGGTCGTGGAAACC TGATCCGCCGCAAGGCGGGCCTGCCGCCGGCAACTTATTTCTCTGGCGGCAAGCTGCAGTGGATCCTGGAAAATGTCGAT GGAGTCCGCGCGGCCGCCGAGAACGGCGACGCATTGTTCGGCACACCGGACACCTGGGTGTTGTGGAATCTGACCGGCGG GCCGCGGGGGGGGGGTGTGCATGTCACCGATGTAACCAACGCCAGCCGGACCATGTTGATGGATCTAGAGACGCTGGACT GGGACGACGAGCTGTTGTCGTTGTTTTCGATACCTCGGGCCATGCTGCCCGAGATCGCATCGTCGGCGCCGTCGGAGCCT TACGGTGTCACGCTGGCGACCGGGCCTGTCGGCGGTGAGGTGCCGATCACCGGAGTTCTCGGTGATCAGCATGCGGCCAT GGTCGGTCAAGTCTGTCTGGCCCCAGGGGAGGCGAAAAACACCTATGGGACCGGCAATTTTCTGCTGCTGAACACCGGTG AAACGATCGTGCGATCGAATAACGGCCTGCTAACCACGGTGTGCTACCAATTCGGGAACGCTAAACCCGTGTACGCGCTT GAAGGTTCGATCGCGGTGACCGGCTCGGCGGTGCAGTGGCTACGCGATCAGCTGGGCATCATCAGCGGCGCCGCACAGAG TGAGGCGCTGGCCCGCCAGGTCCCCGACAACGGCGGCATGTATTTCGTGCCGGCGTTTTCCGGGCTGTTCGCGCCATACT GGCGGTCCGATGCGCGCGGCGCGATCGTCGGGTTGTCGCGGTTCAACACCAACGCGCACCTGGCGCGCGCAACGCTGGAG GCGATCTGCTACCAGAGCCGCGATGTGGTGGACGCCATGGAAGCAGACTCCGGTGTTCGCCTGCAGGTGTTGAAGGTGGA TGGCGGGATCACCGGCAACGACCTGTGTATGCAGATCCAGGCCGACGTGTTGGGTGTGGATGTGGTGCGGCCGGTGGTCG CCGAGACCACCGCACTAGGTGCGGCCTACGCGGCGGGCTTGGCGGTCGGGTTCTGGGCGGCTCCGTCCGATCTGCGGGCC AACTGGCGAGAGGACAAGCGGTGGACACCGACGTGGGACGACGACGAGCGTGCCGCGGGTTATGCCGGCTGGCGCAAGGC GGTGCAGCGGACCCTGGATTGGGTTGACGTGTCCTAG Protein sequence : MSDAILGEQLAESSDFIAAIDQGTTSTRCMIFDHHGAEVARHQLEHEQILPRAGWVEHNPVEIWERTASVLISVLNATNL SPKDIAALGITNQRETTLVWNRHTGRPYYNAIVWQDTRTDRIASALDRDGRGNLIRRKAGLPPATYFSGGKLQWILENVD GVRAAAENGDALFGTPDTWVLWNLTGGPRGGGVHVTDVTNASRTMLMDLETLDWDDELLSLFSIPRAMLPEIASSAPSEP YGVTLATGPVGGEVPITGVLGDQHAAMVGQVCLAPGEAKNTYGTGNFLLLNTGETIVRSNNGLLTTVCYQFGNAKPVYAL EGSIAVTGSAVQWLRDQLGIISGAAQSEALARQVPDNGGMYFVPAFSGLFAPYWRSDARGAIVGLSRFNTNAHLARATLE AICYQSRDVVDAMEADSGVRLQVLKVDGGITGNDLCMQIQADVLGVDVVRPVVAETTALGAAYAAGLAVGFWAAPSDLRA NWREDKRWTPTWDDDERAAGYAGWRKAVQRTLDWVDVS |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| glpK | YP_005139160.1 | glycerol kinase | Not tested | Not named | Protein | 2e-109 | 58 |
