Gene Information

Name : aldA (CDHC02_2011)
Accession : YP_005165789.1
Strain : Corynebacterium diphtheriae HC02
Genome accession: NC_016802
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2166569 - 2168089 bp
Length : 1521 bp
Strand : -
Note : -

DNA sequence :
ATGGCTGTTTATGTATATCCAGGAACGCCAGATGCCGTAGCCAACTACAAGAATCGCTACGACAACTACATCGGCGGCCA
GTGGGTACCACCGGTGGGTGGTGAATACCTCGATAACATCACACCAGTTACTGGCGAAGTGTTCTGTCAAGTGGCACGAG
GAACCGCTGCCGACGTGGAAAAGGCCTTGGATGCAGCGCATGATGCAGCAAAAACATGGGGTCATAGCTCGCCGGCTGAG
CGCGCACTCATTCTGCACCGCATTGCCGATCGCATGGAAGAGCATCTCGAAGAAATCGCCGTTGCCGAAACATGGGACAA
CGGCAAGGCTGTGCGTGAGACGCTCGCCGCCGACATTCCACTGGCCATCGACCACTTCCGCTACTTTGCCGGTGCAATCC
GTGCCCAAGAATCACGAACCTCTCAAATCGACCACAACACGGTGGCCTACCACTTCCATGAGCCCATCGGTGTTGTGGGT
CAGATCATTCCGTGGAACTTCCCACTGCTCATGGCCGCATGGAAGATCGCTCCAGCTCTTGCTGCGGGTAACACGATTGT
GTTGAAGCCTGCGGAGCAAACCCCTGCGTCCATCCTGTTCTGGATCGACATTGTGGGTGACTTGCTTCCTGATGGCGTGC
TCAACATCGTCAACGGTCTGGGTGAGGAAGCTGGTGTGGCGCTATCCTCCTCCAACCGTATTGGCAAGATTGCCTTTACT
GGTTCCACACAGGTGGGCAAGATTATCAATCGTGCCGCTGCCGACAAGATCATCCCCGTCACCTTGGGGCTAGGCGGTAA
GTCGCCGTCGATCTTCTTCGCGGACATCATGGATTACGACGACCCCTTCCGTGAGAAGTGCATTGAGGGCCTTGCTATGT
TCGCACTCAATCAGGGTGAGGTATGTACCTGCCCGTCGCGTGCGTTGGTGCATGAGTCCATCGCGGACGAGTTCCTTGAG
CTGGGTGTCCAACGTGTGAAGAACATCAAGCTCGGCAACCCGCTGGACACGGAAACCATGATGGGTGCCCAAGCCTCCAT
GGAACAAATGGATAAGATCAGTGGCTACCTCGATATTGGCCCGAAGGAGGGCGCTGAGGTGCTCACCGGTGGCCACGTGA
ACAAGATTGACGGTTTGGAAAATGGCTACTATATCGAGCCCACGGTGTTTAAGGGCACGAATGACATGACCATTTTCCGT
GAGGAAATCTTCGGCCCAGTGCTTTCGGTTGCTACCTTCAAGGATTTTGATGAGGCAATCCGCATTGCTAATGACACGAA
CTACGGCCTCGGCGCTGGTGTGTGGACTCGCCATCAGAACACTGCGTATCGTGCCGGACGCGCCATCCAGGCTGGTCGCG
TGTGGGTGAATCAATACCACAATTACCCAGCACACGCAGCGTTCGGAGGCTATAAAGAGTCCGGAATTGGACGTGAGAAT
CACCTCATGATGTTGGATCACTACCAGCAGACAAAGAACCTTCTTGTCTCGTATGATGAGAATCCAACAGGCTTATTTTA
A

Protein sequence :
MAVYVYPGTPDAVANYKNRYDNYIGGQWVPPVGGEYLDNITPVTGEVFCQVARGTAADVEKALDAAHDAAKTWGHSSPAE
RALILHRIADRMEEHLEEIAVAETWDNGKAVRETLAADIPLAIDHFRYFAGAIRAQESRTSQIDHNTVAYHFHEPIGVVG
QIIPWNFPLLMAAWKIAPALAAGNTIVLKPAEQTPASILFWIDIVGDLLPDGVLNIVNGLGEEAGVALSSSNRIGKIAFT
GSTQVGKIINRAAADKIIPVTLGLGGKSPSIFFADIMDYDDPFREKCIEGLAMFALNQGEVCTCPSRALVHESIADEFLE
LGVQRVKNIKLGNPLDTETMMGAQASMEQMDKISGYLDIGPKEGAEVLTGGHVNKIDGLENGYYIEPTVFKGTNDMTIFR
EEIFGPVLSVATFKDFDEAIRIANDTNYGLGAGVWTRHQNTAYRAGRAIQAGRVWVNQYHNYPAHAAFGGYKESGIGREN
HLMMLDHYQQTKNLLVSYDENPTGLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-146 63
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 1e-154 62
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 1e-154 62
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 1e-154 62
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-154 62

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
aldA YP_005165789.1 aldehyde dehydrogenase VFG0082 Protein 8e-147 63