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Name : merA (CDBH8_0070) Accession : YP_005159164.1 Strain : Corynebacterium diphtheriae BH8 Genome accession: NC_016800 Putative virulence/resistance : Resistance Product : mercuric reductase Function : - COG functional category : - COG ID : - EC number : 1.16.1.1 Position : 68767 - 70209 bp Length : 1443 bp Strand : - Note : Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes DNA sequence : ATGCCTGACGTAGCACCAGATTTTGATTTAGCCGTGATCGGTTCCGGAGGCGGCGCCTTCGCCGCCGCCATCCGGGCCAC CAAGCTGGGCAATCGGGTCGTGATGATCGAACGCTCCACGGTGGGCGGGACCTGTGTGAACACCGGGTGCGTTCCCTCCA AAGCCCTGCTGGCCGCCGCCGAAGCCCGGCATGTCGCTGTGGATGCGACCGGAAGGTTCCCCGGGATCAGCACTTCCGCC GCCCCGGTGGACATGGGTGTACTGATAGACGGGAAACGCTCCCTGGTCGAGGGAATGCGCTCGGATAAATACGTGGATCT GGCCGCCGACTACGGATGGGACCTGCGCCAGGGCACCGCGGTGTTCGCCGGCACCCCGGAGGAACCGGTCCTGGAAATCA CCGGACCCGACGGCACCCGCGACTCCCTGACCGCCGCCCATTATCTGGTCGCGACCGGTTCGACCCCGTGGGCACCCCCG GTGCCGGGACTGGATGAAGTCAACTACCTGACCTCGACCACCGCCATGGAACTGAACGAGGTGCCCGAGTCCCTGATCGT CTTCGGCGGCGGGTACGTGGCCCTGGAGCAGGCGCAGCTTTTTGCCCGCCTCGGATCCAAAGTGACCTTGCTGGTCCGCT CCAGGCTTGCCTCGCACGAGGAACCGGAAGCCTCCCGTGCGCTGATGGGCGTCTTCGCCGACGAGGGCATCCGCGTGGTC CGCCGCGCAGCCGTAACTTCGGTCCGCACAGATCCCGCCGGTGCAGAGGTCCTTGTCACCGCCACGGTCGCCGGGGGCCA GGAGGAATTCCGCGCCGCAAAGCTGCTGGTAGCCACCGGCCGACGCGCCGTCACCGACGGACTGAACCTGGACGCCGTCG GCGTCAAGACCGGCGACACCGGCCAGATCCTGGTCGAGAGCACACTCGCCAGCTCCAACCCCAGGATCTGGGCCGCAGGG GATGTGACCGGGCACCGAGAATTCGTCTACGTCGCGTCCGCCCACGGAACCCTGATGGTGGAGAACGCCTTCAACAACGC CGGGCGCGAGGTCGACTACCGGCACCTGCCCCGCGTGACGTTCACCAGCCCGACACTGGCCGCGGTCGGCATGACCGACA AGGAAGCCAACGAGGCGGGCATCCGGTGTGAATGCCGGGTCCTGCCCCTGGAATACGTTCCCCGGGCACTGGTGAACCGG GACACCCGCGGCTTCATCAAAATCGTCGCCGACGCCGACAACGGACGGATTGTGGGGATCACCGCCGTCGGCAAGGAGGC CGGTGACCTGGCCGCCGCCGGAGTCTACATCCTCGAGGCCGGCATGACCGTTGACCAGGTCGCGAACCTCTGGTGCCCAT ACCTGACCATGGCCGAAGGGATCAAAATCGCCGCACAGTCCTTCACCACCGACGTCTCCAAACTCTCCTGCTGCGCCTCC TGA Protein sequence : MPDVAPDFDLAVIGSGGGAFAAAIRATKLGNRVVMIERSTVGGTCVNTGCVPSKALLAAAEARHVAVDATGRFPGISTSA APVDMGVLIDGKRSLVEGMRSDKYVDLAADYGWDLRQGTAVFAGTPEEPVLEITGPDGTRDSLTAAHYLVATGSTPWAPP VPGLDEVNYLTSTTAMELNEVPESLIVFGGGYVALEQAQLFARLGSKVTLLVRSRLASHEEPEASRALMGVFADEGIRVV RRAAVTSVRTDPAGAEVLVTATVAGGQEEFRAAKLLVATGRRAVTDGLNLDAVGVKTGDTGQILVESTLASSNPRIWAAG DVTGHREFVYVASAHGTLMVENAFNNAGREVDYRHLPRVTFTSPTLAAVGMTDKEANEAGIRCECRVLPLEYVPRALVNR DTRGFIKIVADADNGRIVGITAVGKEAGDLAAAGVYILEAGMTVDQVANLWCPYLTMAEGIKIAAQSFTTDVSKLSCCAS |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| merA | BAB47642.1 | mercuric reductase | Not tested | Type-III SCCmec | Protein | 5e-86 | 43 |
| SE0085 | NP_763640.1 | dihydrolipoamide dehydrogenase | Not tested | SCCpbp4 | Protein | 6e-86 | 43 |
| merA | AAN62178.1 | mercuric (Hg(II)) reductase | Not tested | PAGI-2(C) | Protein | 6e-68 | 43 |
| merA | ABQ57371.1 | MerA | Not tested | SGI1 | Protein | 1e-68 | 42 |
| merA | AGK07021.1 | MerA | Not tested | SGI1 | Protein | 1e-68 | 42 |
| merA | AGK07079.1 | MerA | Not tested | SGI1 | Protein | 1e-68 | 42 |
| merA | ACN81005.1 | MerA Hg(II) mercuric ion reductase | Not tested | AbaR5 | Protein | 5e-67 | 42 |
| merA | CAJ77060.1 | Mercuric ion reductase | Not tested | AbaR1 | Protein | 6e-67 | 42 |
| merA | AFG30120.1 | MerA | Not tested | PAGI-2 | Protein | 6e-67 | 41 |
| merA | YP_006098387.1 | mercuric ion reductase | Not tested | Tn2411 | Protein | 8e-67 | 41 |
| merA | AET25397.1 | MerA | Not tested | PAGI-2(C) | Protein | 6e-67 | 41 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| merA | YP_005159164.1 | mercuric reductase | BAC0224 | Protein | 9e-83 | 45 |
| merA | YP_005159164.1 | mercuric reductase | BAC0651 | Protein | 3e-86 | 43 |
| merA | YP_005159164.1 | mercuric reductase | BAC0652 | Protein | 6e-69 | 42 |
