Gene Information

Name : clpC (CDBH8_1937)
Accession : YP_005161021.1
Strain : Corynebacterium diphtheriae BH8
Genome accession: NC_016800
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease ATP-binding subunit
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2018978 - 2021611 bp
Length : 2634 bp
Strand : -
Note : -

DNA sequence :
ATGTTCGAGCGGTTTACCGATCGTGCACGTCGCGTTATCGTTCTGGCACAGGAAGAAGCGCGCGGCCTCAATCACAATTA
CATCGGCACCGAGCACATCCTGCTCGGACTTATTCACGAGGGCGAGGGCGTGGCCGCTAAGGCGCTCGAGTCCATGGGCA
TCTCCCTTGAAGCAGTACGCCAAGAGGTAGAAGAAATCATCGGCCACGGCTCCGAGCCACCAGCTGGCCACATTCCTTTT
ACTCCACGTGCCAAGAAGGTACTTGAGCTCTCCTTGCGTGAGGGTCTGCAGATGGGACATAAGTACATCGGTACTGAGTT
CCTGCTGCTCGGCCTTATCCGTGAAGGCGACGGCGTAGCCGCACAAGTTTTGGTCAAGCTCGGCGCTGACCTGCCCCGTG
TACGCCAGCAGGTTATCCAGCTTCTTTCCGGCTACGAGGGTGGCGAAAGCCCAGAAAACAATAACGAGGGCGAGGCTGTG
GGTGCTGGTACTGGCGCTGGCCGCGCTGGCCGCGGTGGTGGCGCAGGCGAGCGCTCCAACTCCTTGGTTTTGGACCAGTT
TGGTCGCAACCTCACCCAGGCTGCTAAGGAAGGCAAGCTGGATCCTGTGGTGGGTCGTGAGCAGGAAATTGAGCGCATCA
TGCAGGTGCTCTCACGTCGTACCAAGAACAACCCAGTTCTTATCGGAGAGCCAGGTGTTGGTAAGACCGCTGTTGTAGAA
GGCCTAGCTCTAGACATCGTTAATGGCAAGGTGCCAGAAACGCTGAAAGACAAGCAGGTTTACTCTCTTGACCTCGGCTC
CTTGGTGGCAGGTTCGCGCTACCGTGGTGACTTCGAAGAGCGCCTGAAGAAGGTTCTCAAGGAGATCAACCAGCGTGGCG
ACATCATCTTGTTCATCGATGAGATCCACACCCTCGTCGGTGCCGGTGCCGCAGAAGGCGCTATCGACGCTGCCAGCTTG
CTCAAACCAAAACTGGCTCGTGGTGAGCTACAGACCATCGGTGCTACCACTTTGGACGAGTACCGCAAGCACATCGAAAA
GGACGCCGCACTTGAGCGTCGTTTCCAGCCAGTGCAGGTTCCAGAGCCTTCCGTCGATATGACCATCGAGATCCTCAAGG
GTCTACGTGACCGCTACGAGGCACACCACCGCGTCTCCATCACCGATGGGGCTCTCGCAGCAGCAGCACAGCTGTCCGAT
CGCTACATCAACGATCGCTTCTTGCCAGATAAGGCCGTTGACCTTATCGACGAAGCCGGCGCACGCATGCGTATCAAGCG
CATGACCGCACCGGAATCCATCCGCAAGGTAGACGATCAGATCGCGGAAGTCCGTCGTGAGAAGGAAGCCGCAATCGACG
CCCAAGACTTTGAAAAGGCCGCAGGCCTGCGCGACACCGAGCGCAAGTTAGGCGAAGAGCGCGCTGAGAAAGAAAAGCAG
TGGCGCTCCGGCAGCCTAGAAGACATCGCAGAAGTCGGCGAAGAGCAAATCGCTGAGGTGCTGGGCAACTGGACTGGCAT
CCCAGTGTTCAAGCTGACCGAGGAAGAATCCTCCCGTCTGCTGCACATGGAAGAGGAGCTACACAAGCGCATCATCGGCC
AAGACGATGCCGTCAAGAGTGTTTCTCGCGCCATCCGCCGCACCCGCGCTGGCCTCAAGGACCCACGCCGTCCTTCCGGC
TCCTTCATCTTCGCCGGCCCATCTGGTGTGGGTAAGACCGAGCTATCCAAGTCACTGGCCAACTTCCTGTTCGGCGACGA
CGACGCCTTGATCCAGATCGACATGGGCGAGTTCCACGACCGCTTCACTGCGTCCCGTCTGTTCGGTGCCCCTCCTGGAT
ATGTGGGCTACGACGAAGGCGGTCAGCTCACCGAAAAGGTCCGCCGCAAGCCATTCTCCGTCGTGCTTTTCGACGAAATC
GAAAAGGCGCACAAGGAGATCTACAACACCTTGCTGCAGGTCCTCGAAGAAGGTCGCCTCACCGACGGCCAAGGCCGTGT
GGTGGACTTCAAGAACACCGTGCTGATCTTCACCTCCAACCTGGGTACCCAAGACATCTCTAAGGCTGTGGGCATGGGCT
TTAGCTCTGTCGGCGAGCACGATGCCGACGGTCAGTACGACCGCATGAAGCAGAAGGTCAACGACGAGCTGAAGAAGCAC
TTCCGCCCTGAGTTCCTCAACCGTATCGACGAAATCGTGGTATTCCACCAGCTCACCCAAGAGCAGATCGTCGAAATGGT
GGACCTGCTCATCGGACGCGTATCCAAGGCACTTGCTCAAAAAGACATGGGCATCGAGCTCACCGAAAAGGCCAAGAACC
TGCTGGCAAAGCGTGGATTCGATCCAGTACTGGGTGCACGACCATTGCGTCGCACCATCCAGCGCGAGATCGAAGACGTA
CTCTCCGAGAAGATCCTCTTCGGTGAGGTCGGCGCTGGTGAGATCGTCACCGTGGATGTTGAAGGCTGGGACGGCGAATC
CAAGGAAACCGACAAGGCTTCCTTCACCTTCACCCCACGCGTGAAGCCGCTGCCAGACGAGTTCGAAGAGGCAACCCCAT
CTGAGGAAGCTCAAGAAGCAGTGATTAACGCTGCTGAGACTGAGGTTCCAGAAGAAGCCAACATCGAAAACTAA

Protein sequence :
MFERFTDRARRVIVLAQEEARGLNHNYIGTEHILLGLIHEGEGVAAKALESMGISLEAVRQEVEEIIGHGSEPPAGHIPF
TPRAKKVLELSLREGLQMGHKYIGTEFLLLGLIREGDGVAAQVLVKLGADLPRVRQQVIQLLSGYEGGESPENNNEGEAV
GAGTGAGRAGRGGGAGERSNSLVLDQFGRNLTQAAKEGKLDPVVGREQEIERIMQVLSRRTKNNPVLIGEPGVGKTAVVE
GLALDIVNGKVPETLKDKQVYSLDLGSLVAGSRYRGDFEERLKKVLKEINQRGDIILFIDEIHTLVGAGAAEGAIDAASL
LKPKLARGELQTIGATTLDEYRKHIEKDAALERRFQPVQVPEPSVDMTIEILKGLRDRYEAHHRVSITDGALAAAAQLSD
RYINDRFLPDKAVDLIDEAGARMRIKRMTAPESIRKVDDQIAEVRREKEAAIDAQDFEKAAGLRDTERKLGEERAEKEKQ
WRSGSLEDIAEVGEEQIAEVLGNWTGIPVFKLTEEESSRLLHMEEELHKRIIGQDDAVKSVSRAIRRTRAGLKDPRRPSG
SFIFAGPSGVGKTELSKSLANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPGYVGYDEGGQLTEKVRRKPFSVVLFDEI
EKAHKEIYNTLLQVLEEGRLTDGQGRVVDFKNTVLIFTSNLGTQDISKAVGMGFSSVGEHDADGQYDRMKQKVNDELKKH
FRPEFLNRIDEIVVFHQLTQEQIVEMVDLLIGRVSKALAQKDMGIELTEKAKNLLAKRGFDPVLGARPLRRTIQREIEDV
LSEKILFGEVGAGEIVTVDVEGWDGESKETDKASFTFTPRVKPLPDEFEEATPSEEAQEAVINAAETEVPEEANIEN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 99
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 1e-98 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpC YP_005161021.1 ATP-dependent Clp protease ATP-binding subunit VFG0079 Protein 0.0 58
clpC YP_005161021.1 ATP-dependent Clp protease ATP-binding subunit VFG0080 Protein 1e-150 50
clpC YP_005161021.1 ATP-dependent Clp protease ATP-binding subunit VFG2084 Protein 3e-97 41