Gene Information

Name : frgC (CDBH8_1035)
Accession : YP_005160125.1
Strain : Corynebacterium diphtheriae BH8
Genome accession: NC_016800
Putative virulence/resistance : Virulence
Product : iron-siderophore uptake system ATP-binding component
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1040106 - 1040927 bp
Length : 822 bp
Strand : -
Note : -

DNA sequence : 
ATGACCAGCACTTCCCCCATTCTTCGTACCGATTCCGTCACATTGGCGTGGGATAAGCACACAGTAAGTACTGATCTCAC
GGTCGAGGTGCCGCAAGGACACTTCACAGCCATCATTGGGCCAAATGGTTGTGGAAAATCCACACTATTAAAAAGCTTCG
CCCGAATTCTTCAACCACACACTGGGCAAGTATATCTAGGTGACAACCCGCTGGATTCTTTGCACACAAAATACATAGCC
CAACGTATCGCTTTGCTGCCACAAACAGCACTTGCACCAGCTGATATTACTGTCGAAGAACTCGTAGGCAGAGGTCGTTT
CCCCTACCAAACCCTTCTGCGACAGTGGTCAACTAAGGATGCTCAAGCAGTTGATTCCGCCCTCCTAGCAACCGGCACGG
CACAACTACGCCACCGCCGCGTTACTGAACTTTCTGGCGGCCAACGTCAACGAGTCTGGCTCGCAATGGTGCTGGCCCAA
AACACACCCGTAGTTCTCCTAGACGAGCCCACAACGTATCTCGATGTAGCCCACCAATACCAGCTTTTAGAGCTCGCCCG
AGCACTGCGGCAACAGCTCGGACGAACTATTGTGACCGTCTTGCACGATCTACAACAGGCTGTTAGATATGCCGACCATC
TTATTGTGATGAAAGGTGGCGCAGTCTATGCCGAAGGCGCTCCAAGCAGCATCATGACACCACAATTGATTTCCGAGGTA
TTTGAAATCAATGTTGATGTTCATACCATCGACGATCATGTGGTGATCGTGCCCAAAACCATGCCTCAACCTGATGTATC
AGTCCTAGAAAATCTGCAATAG

Protein sequence : 
MTSTSPILRTDSVTLAWDKHTVSTDLTVEVPQGHFTAIIGPNGCGKSTLLKSFARILQPHTGQVYLGDNPLDSLHTKYIA
QRIALLPQTALAPADITVEELVGRGRFPYQTLLRQWSTKDAQAVDSALLATGTAQLRHRRVTELSGGQRQRVWLAMVLAQ
NTPVVLLDEPTTYLDVAHQYQLLELARALRQQLGRTIVTVLHDLQQAVRYADHLIVMKGGAVYAEGAPSSIMTPQLISEV
FEINVDVHTIDDHVVIVPKTMPQPDVSVLENLQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
fagC YP_005680307.1 ATP binding cytoplasmic membrane protein Not tested PiCp 1 Protein 9e-78 65
fagC YP_003782430.1 ABC transporter ATP-binding protein Not tested PiCp 1 Protein 9e-78 65
fagC YP_005682397.1 ATP binding cytoplasmic membrane protein Virulence PiCp 1 Protein 9e-78 65
fagC YP_005684488.1 ATP binding cytoplasmic membrane protein Not tested PiCp 1 Protein 9e-78 65
fecE AAL08451.1 ATP-binding protein FecE Virulence SRL Protein 6e-53 52
iusE YP_005143742.1 iron ABC transporter ATP-binding protein Virulence Not named Protein 2e-51 45
SPN23F_09560 YP_002510939.1 ferric siderophore ABC transporter ATP-binding protein Virulence PPI-1 Protein 3e-45 41
SP_1035 NP_345510.1 iron-compound ABC transporter ATP-binding protein Not tested PPI-1 Protein 3e-45 41
ciuD YP_005683346.1 Iron ABC transporter ATP-binding protein Virulence PiCp 4 Protein 8e-43 41
ciuD YP_003783391.1 iron ABC transporter ATP-binding protein Virulence PiCp 4 Protein 8e-43 41
ciuD YP_005685432.1 Iron ABC transporter ATP-binding protein Virulence PiCp 4 Protein 8e-43 41
ciuD YP_005681255.1 Iron ABC transporter ATP-binding protein Virulence PiCp 4 Protein 8e-43 41
DIP0585 NP_938961.1 iron ABC transporter ATP-binding protein Virulence Not named Protein 3e-38 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
frgC YP_005160125.1 iron-siderophore uptake system ATP-binding component BAC0164 Protein 4e-53 52

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
frgC YP_005160125.1 iron-siderophore uptake system ATP-binding component VFG1042 Protein 4e-53 52
frgC YP_005160125.1 iron-siderophore uptake system ATP-binding component VFG0925 Protein 2e-57 52